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Journal Abstract Search

430 related items for PubMed ID: 25344906

  • 1. Thymoquinone Pretreatment Overcomes the Insensitivity and Potentiates the Antitumor Effect of Gemcitabine Through Abrogation of Notch1, PI3K/Akt/mTOR Regulated Signaling Pathways in Pancreatic Cancer.
    Mu GG, Zhang LL, Li HY, Liao Y, Yu HG.
    Dig Dis Sci; 2015 Apr; 60(4):1067-80. PubMed ID: 25344906
    [Abstract] [Full Text] [Related]

  • 2. Everolimus regulates the activity of gemcitabine-resistant pancreatic cancer cells by targeting the Warburg effect via PI3K/AKT/mTOR signaling.
    Cui J, Guo Y, Wu H, Xiong J, Peng T.
    Mol Med; 2021 Apr 13; 27(1):38. PubMed ID: 33849427
    [Abstract] [Full Text] [Related]

  • 3. Antitumor activity of gemcitabine and oxaliplatin is augmented by thymoquinone in pancreatic cancer.
    Banerjee S, Kaseb AO, Wang Z, Kong D, Mohammad M, Padhye S, Sarkar FH, Mohammad RM.
    Cancer Res; 2009 Jul 01; 69(13):5575-83. PubMed ID: 19549912
    [Abstract] [Full Text] [Related]

  • 4. Coix seed emulsion synergistically enhances the antitumor activity of gemcitabine in pancreatic cancer through abrogation of NF-κB signaling.
    Qian Y, Yang B, Xiong Y, Gu M.
    Oncol Rep; 2016 Sep 01; 36(3):1517-25. PubMed ID: 27459907
    [Abstract] [Full Text] [Related]

  • 5. The enhancement of Tetrandrine to gemcitabine-resistant PANC-1 cytochemical sensitivity involves the promotion of PI3K/Akt/mTOR-mediated apoptosis and AMPK-regulated autophagy.
    Song J, Xu J, Guo J, Shang Y, Wang J, Wang T.
    Acta Histochem; 2021 Sep 01; 123(6):151769. PubMed ID: 34416437
    [Abstract] [Full Text] [Related]

  • 6. Hypoxia potentiates gemcitabine-induced stemness in pancreatic cancer cells through AKT/Notch1 signaling.
    Zhang Z, Han H, Rong Y, Zhu K, Zhu Z, Tang Z, Xiong C, Tao J.
    J Exp Clin Cancer Res; 2018 Nov 28; 37(1):291. PubMed ID: 30486896
    [Abstract] [Full Text] [Related]

  • 7. CDK-4 inhibitor P276 sensitizes pancreatic cancer cells to gemcitabine-induced apoptosis.
    Subramaniam D, Periyasamy G, Ponnurangam S, Chakrabarti D, Sugumar A, Padigaru M, Weir SJ, Balakrishnan A, Sharma S, Anant S.
    Mol Cancer Ther; 2012 Jul 28; 11(7):1598-608. PubMed ID: 22532602
    [Abstract] [Full Text] [Related]

  • 8. Targeting Pancreatic Cancer with Novel Nicolaioidesin C Derivatives: Molecular Mechanism, In Vitro, and In Vivo Evaluations.
    Yamazaki T, Phan ND, Maneenet J, Yamagishi M, Nishikawa Y, Okada T, Okumura T, Toyooka N, Fujii T, Awale S.
    J Med Chem; 2024 Aug 22; 67(16):14313-14328. PubMed ID: 39106150
    [Abstract] [Full Text] [Related]

  • 9. Ursolic acid inhibits growth and induces apoptosis in gemcitabine-resistant human pancreatic cancer via the JNK and PI3K/Akt/NF-κB pathways.
    Li J, Liang X, Yang X.
    Oncol Rep; 2012 Aug 22; 28(2):501-10. PubMed ID: 22641480
    [Abstract] [Full Text] [Related]

  • 10. Molecular evidence for increased antitumor activity of gemcitabine by genistein in vitro and in vivo using an orthotopic model of pancreatic cancer.
    Banerjee S, Zhang Y, Ali S, Bhuiyan M, Wang Z, Chiao PJ, Philip PA, Abbruzzese J, Sarkar FH.
    Cancer Res; 2005 Oct 01; 65(19):9064-72. PubMed ID: 16204081
    [Abstract] [Full Text] [Related]

  • 11. Targeted apoptotic effects of thymoquinone and tamoxifen on XIAP mediated Akt regulation in breast cancer.
    Rajput S, Kumar BN, Sarkar S, Das S, Azab B, Santhekadur PK, Das SK, Emdad L, Sarkar D, Fisher PB, Mandal M.
    PLoS One; 2013 Oct 01; 8(4):e61342. PubMed ID: 23613836
    [Abstract] [Full Text] [Related]

  • 12. Arginine deiminase augments the chemosensitivity of argininosuccinate synthetase-deficient pancreatic cancer cells to gemcitabine via inhibition of NF-κB signaling.
    Liu J, Ma J, Wu Z, Li W, Zhang D, Han L, Wang F, Reindl KM, Wu E, Ma Q.
    BMC Cancer; 2014 Sep 20; 14():686. PubMed ID: 25240403
    [Abstract] [Full Text] [Related]

  • 13. Antiproliferative Effects of Matricine in Gemcitabine-Resistant Human Pancreatic Carcinoma Cells Are Mediated via Mitochondrial-Mediated Apoptosis, Inhibition of Cell Migration, Invasion Suppression, and Mammalian Target of Rapamycin (mTOR)-TOR/PI3K/AKT Signalling Pathway.
    Fang K, Wang L, Chen L, Liu T, Fang Z.
    Med Sci Monit; 2019 Apr 21; 25():2943-2949. PubMed ID: 31005960
    [Abstract] [Full Text] [Related]

  • 14. Inhibition of AKT2 enhances sensitivity to gemcitabine via regulating PUMA and NF-κB signaling pathway in human pancreatic ductal adenocarcinoma.
    Chen D, Niu M, Jiao X, Zhang K, Liang J, Zhang D.
    Int J Mol Sci; 2012 Apr 21; 13(1):1186-1208. PubMed ID: 22312312
    [Abstract] [Full Text] [Related]

  • 15. Escin augments the efficacy of gemcitabine through down-regulation of nuclear factor-κB and nuclear factor-κB-regulated gene products in pancreatic cancer both in vitro and in vivo.
    Wang YW, Wang SJ, Zhou YN, Pan SH, Sun B.
    J Cancer Res Clin Oncol; 2012 May 21; 138(5):785-97. PubMed ID: 22270965
    [Abstract] [Full Text] [Related]

  • 16. Molecular mechanisms and signaling pathways of black cumin (Nigella sativa) and its active constituent, thymoquinone: a review.
    Sadeghi E, Imenshahidi M, Hosseinzadeh H.
    Mol Biol Rep; 2023 Jun 21; 50(6):5439-5454. PubMed ID: 37155017
    [Abstract] [Full Text] [Related]

  • 17. Insulin-like growth factor 1 receptor promotes the growth and chemoresistance of pancreatic cancer.
    Tian X, Hao K, Qin C, Xie K, Xie X, Yang Y.
    Dig Dis Sci; 2013 Sep 21; 58(9):2705-12. PubMed ID: 23589145
    [Abstract] [Full Text] [Related]

  • 18. Thymoquinone induces G2/M arrest, inactivates PI3K/Akt and nuclear factor-κB pathways in human cholangiocarcinomas both in vitro and in vivo.
    Xu D, Ma Y, Zhao B, Li S, Zhang Y, Pan S, Wu Y, Wang J, Wang D, Pan H, Liu L, Jiang H.
    Oncol Rep; 2014 May 21; 31(5):2063-70. PubMed ID: 24603952
    [Abstract] [Full Text] [Related]

  • 19. GDC-0980 (apitolisib) treatment with gemcitabine and/or cisplatin synergistically reduces cholangiocarcinoma cell growth by suppressing the PI3K/Akt/mTOR pathway.
    Jang DK, Lee YG, Chan Chae Y, Lee JK, Paik WH, Lee SH, Kim YT, Ryu JK.
    Biochem Biophys Res Commun; 2020 Sep 03; 529(4):1242-1248. PubMed ID: 32819590
    [Abstract] [Full Text] [Related]

  • 20. Intracellular KRAS-specific antibody enhances the anti-tumor efficacy of gemcitabine in pancreatic cancer by inducing endosomal escape.
    Lee JE, Kang YW, Jung KH, Son MK, Shin SM, Kim JS, Kim SJ, Fang Z, Yan HH, Park JH, Yoon YC, Han B, Cheon MJ, Woo MG, Seo MS, Lim JH, Kim YS, Hong SS.
    Cancer Lett; 2021 Jun 01; 507():97-111. PubMed ID: 33744388
    [Abstract] [Full Text] [Related]

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