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613 related items for PubMed ID: 25375379

  • 1. Cafestol overcomes ABT-737 resistance in Mcl-1-overexpressed renal carcinoma Caki cells through downregulation of Mcl-1 expression and upregulation of Bim expression.
    Woo SM, Min KJ, Seo BR, Nam JO, Choi KS, Yoo YH, Kwon TK.
    Cell Death Dis; 2014 Nov 06; 5(11):e1514. PubMed ID: 25375379
    [Abstract] [Full Text] [Related]

  • 2. Platinum compounds sensitize ovarian carcinoma cells to ABT-737 by modulation of the Mcl-1/Noxa axis.
    Simonin K, N'Diaye M, Lheureux S, Loussouarn C, Dutoit S, Briand M, Giffard F, Brotin E, Blanc-Fournier C, Poulain L.
    Apoptosis; 2013 Apr 06; 18(4):492-508. PubMed ID: 23344663
    [Abstract] [Full Text] [Related]

  • 3. PI3K/mTOR dual inhibitor NVP-BEZ235 decreases Mcl-1 expression and sensitizes ovarian carcinoma cells to Bcl-xL-targeting strategies, provided that Bim expression is induced.
    Jebahi A, Villedieu M, Pétigny-Lechartier C, Brotin E, Louis MH, Abeilard E, Giffard F, Guercio M, Briand M, Gauduchon P, Lheureux S, Poulain L.
    Cancer Lett; 2014 Jun 28; 348(1-2):38-49. PubMed ID: 24650799
    [Abstract] [Full Text] [Related]

  • 4. Proteasomal degradation of Mcl-1 by maritoclax induces apoptosis and enhances the efficacy of ABT-737 in melanoma cells.
    Pandey MK, Gowda K, Doi K, Sharma AK, Wang HG, Amin S.
    PLoS One; 2013 Jun 28; 8(11):e78570. PubMed ID: 24223823
    [Abstract] [Full Text] [Related]

  • 5. YM155 enhances ABT-737-mediated apoptosis through Mcl-1 downregulation in Mcl-1-overexpressed cancer cells.
    Woo SM, Min KJ, Seo BR, Seo YH, Jeong YJ, Kwon TK.
    Mol Cell Biochem; 2017 May 28; 429(1-2):91-102. PubMed ID: 28120212
    [Abstract] [Full Text] [Related]

  • 6. Cafestol, a coffee-specific diterpene, induces apoptosis in renal carcinoma Caki cells through down-regulation of anti-apoptotic proteins and Akt phosphorylation.
    Choi MJ, Park EJ, Oh JH, Min KJ, Yang ES, Kim YH, Lee TJ, Kim SH, Choi YH, Park JW, Kwon TK.
    Chem Biol Interact; 2011 Apr 25; 190(2-3):102-8. PubMed ID: 21334318
    [Abstract] [Full Text] [Related]

  • 7. Eupafolin enhances TRAIL-mediated apoptosis through cathepsin S-induced down-regulation of Mcl-1 expression and AMPK-mediated Bim up-regulation in renal carcinoma Caki cells.
    Han MA, Min KJ, Woo SM, Seo BR, Kwon TK.
    Oncotarget; 2016 Oct 04; 7(40):65707-65720. PubMed ID: 27582546
    [Abstract] [Full Text] [Related]

  • 8. Dual inhibition of Bcl-2 and Bcl-xL strikingly enhances PI3K inhibition-induced apoptosis in human myeloid leukemia cells through a GSK3- and Bim-dependent mechanism.
    Rahmani M, Aust MM, Attkisson E, Williams DC, Ferreira-Gonzalez A, Grant S.
    Cancer Res; 2013 Feb 15; 73(4):1340-51. PubMed ID: 23243017
    [Abstract] [Full Text] [Related]

  • 9. Influence of Bcl-2 family members on the cellular response of small-cell lung cancer cell lines to ABT-737.
    Tahir SK, Yang X, Anderson MG, Morgan-Lappe SE, Sarthy AV, Chen J, Warner RB, Ng SC, Fesik SW, Elmore SW, Rosenberg SH, Tse C.
    Cancer Res; 2007 Feb 01; 67(3):1176-83. PubMed ID: 17283153
    [Abstract] [Full Text] [Related]

  • 10. Ionizing radiation sensitizes breast cancer cells to Bcl-2 inhibitor, ABT-737, through regulating Mcl-1.
    Wu H, Schiff DS, Lin Y, Neboori HJ, Goyal S, Feng Z, Haffty BG.
    Radiat Res; 2014 Dec 01; 182(6):618-25. PubMed ID: 25409124
    [Abstract] [Full Text] [Related]

  • 11. Aspirin restores ABT-737-mediated apoptosis in human renal carcinoma cells.
    Ou YC, Li JR, Wang JD, Chen WY, Kuan YH, Yang CP, Liao SL, Lu HC, Chen CJ.
    Biochem Biophys Res Commun; 2018 Jul 12; 502(2):187-193. PubMed ID: 29792865
    [Abstract] [Full Text] [Related]

  • 12. The mTORC1/2 Inhibitor AZD8055 Strengthens the Efficiency of the MEK Inhibitor Trametinib to Reduce the Mcl-1/[Bim and Puma] ratio and to Sensitize Ovarian Carcinoma Cells to ABT-737.
    Pétigny-Lechartier C, Duboc C, Jebahi A, Louis MH, Abeilard E, Denoyelle C, Gauduchon P, Poulain L, Villedieu M.
    Mol Cancer Ther; 2017 Jan 12; 16(1):102-115. PubMed ID: 27980105
    [Abstract] [Full Text] [Related]

  • 13. Clitocine induces apoptosis and enhances the lethality of ABT-737 in human colon cancer cells by disrupting the interaction of Mcl-1 and Bak.
    Sun JG, Xiang J, Zeng XL, Li X, Wu P, Fung KP, Liu FY.
    Cancer Lett; 2014 Dec 28; 355(2):253-63. PubMed ID: 25304383
    [Abstract] [Full Text] [Related]

  • 14. Apigenin sensitizes colon cancer cells to antitumor activity of ABT-263.
    Shao H, Jing K, Mahmoud E, Huang H, Fang X, Yu C.
    Mol Cancer Ther; 2013 Dec 28; 12(12):2640-50. PubMed ID: 24126433
    [Abstract] [Full Text] [Related]

  • 15. Norcantharidin enhances ABT-737-induced apoptosis in hepatocellular carcinoma cells by transcriptional repression of Mcl-1.
    Zhang S, Li G, Ma X, Wang Y, Liu G, Feng L, Zhao Y, Zhang G, Wu Y, Ye X, Qin B, Lu J.
    Cell Signal; 2012 Sep 28; 24(9):1803-9. PubMed ID: 22609455
    [Abstract] [Full Text] [Related]

  • 16. MEK inhibition enhances ABT-737-induced leukemia cell apoptosis via prevention of ERK-activated MCL-1 induction and modulation of MCL-1/BIM complex.
    Konopleva M, Milella M, Ruvolo P, Watts JC, Ricciardi MR, Korchin B, McQueen T, Bornmann W, Tsao T, Bergamo P, Mak DH, Chen W, McCubrey J, Tafuri A, Andreeff M.
    Leukemia; 2012 Apr 28; 26(4):778-87. PubMed ID: 22064351
    [Abstract] [Full Text] [Related]

  • 17. The Bcl-xL inhibitor, ABT-737, efficiently induces apoptosis and suppresses growth of hepatoma cells in combination with sorafenib.
    Hikita H, Takehara T, Shimizu S, Kodama T, Shigekawa M, Iwase K, Hosui A, Miyagi T, Tatsumi T, Ishida H, Li W, Kanto T, Hiramatsu N, Hayashi N.
    Hepatology; 2010 Oct 28; 52(4):1310-21. PubMed ID: 20799354
    [Abstract] [Full Text] [Related]

  • 18. EGFR signaling defines Mcl⁻1 survival dependency in neuroblastoma.
    Nalluri S, Peirce SK, Tanos R, Abdella HA, Karmali D, Hogarty MD, Goldsmith KC.
    Cancer Biol Ther; 2015 Oct 28; 16(2):276-86. PubMed ID: 25756510
    [Abstract] [Full Text] [Related]

  • 19. Bim upregulation by histone deacetylase inhibitors mediates interactions with the Bcl-2 antagonist ABT-737: evidence for distinct roles for Bcl-2, Bcl-xL, and Mcl-1.
    Chen S, Dai Y, Pei XY, Grant S.
    Mol Cell Biol; 2009 Dec 28; 29(23):6149-69. PubMed ID: 19805519
    [Abstract] [Full Text] [Related]

  • 20. Mcl-1 is an important therapeutic target for oral squamous cell carcinomas.
    Maji S, Samal SK, Pattanaik L, Panda S, Quinn BA, Das SK, Sarkar D, Pellecchia M, Fisher PB, Dash R.
    Oncotarget; 2015 Jun 30; 6(18):16623-37. PubMed ID: 26009874
    [Abstract] [Full Text] [Related]

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