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Journal Abstract Search

818 related items for PubMed ID: 25378907

  • 21. Cyanobiphenyls: Novel H3 receptor ligands with cholinesterase and MAO B inhibitory activity as multitarget compounds for potential treatment of Alzheimer's disease.
    Godyń J, Zaręba P, Łażewska D, Stary D, Reiner-Link D, Frank A, Latacz G, Mogilski S, Kaleta M, Doroz-Płonka A, Lubelska A, Honkisz-Orzechowska E, Olejarz-Maciej A, Handzlik J, Stark H, Kieć-Kononowicz K, Malawska B, Bajda M.
    Bioorg Chem; 2021 Sep; 114():105129. PubMed ID: 34217977
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  • 22. Donepezil-butylated hydroxytoluene (BHT) hybrids as Anti-Alzheimer's disease agents with cholinergic, antioxidant, and neuroprotective properties.
    Cai P, Fang SQ, Yang HL, Yang XL, Liu QH, Kong LY, Wang XB.
    Eur J Med Chem; 2018 Sep 05; 157():161-176. PubMed ID: 30096650
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  • 23. Novel AP2238-clorgiline hybrids as multi-target agents for the treatment of Alzheimer's disease: Design, synthesis, and biological evaluation.
    Zhong G, Guo J, Pang C, Su D, Tang C, Jing L, Zhang F, He P, Yan Y, Chen Z, Liu J, Jiang N.
    Bioorg Chem; 2023 Jan 05; 130():106224. PubMed ID: 36332315
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  • 24. Dual functional cholinesterase and MAO inhibitors for the treatment of Alzheimer's disease: synthesis, pharmacological analysis and molecular modeling of homoisoflavonoid derivatives.
    Wang Y, Sun Y, Guo Y, Wang Z, Huang L, Li X.
    J Enzyme Inhib Med Chem; 2016 Jan 05; 31(3):389-97. PubMed ID: 25798687
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  • 25. Design, synthesis and biological evaluation of phthalimide-alkylamine derivatives as balanced multifunctional cholinesterase and monoamine oxidase-B inhibitors for the treatment of Alzheimer's disease.
    Sang Z, Wang K, Wang H, Yu L, Wang H, Ma Q, Ye M, Han X, Liu W.
    Bioorg Med Chem Lett; 2017 Nov 15; 27(22):5053-5059. PubMed ID: 29033232
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  • 26. Synthesis of donepezil-based multifunctional agents for the treatment of Alzheimer's disease.
    Yerdelen KO, Koca M, Anil B, Sevindik H, Kasap Z, Halici Z, Turkaydin K, Gunesacar G.
    Bioorg Med Chem Lett; 2015 Dec 01; 25(23):5576-82. PubMed ID: 26514744
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  • 27. 4,6-Diphenylpyrimidine Derivatives as Dual Inhibitors of Monoamine Oxidase and Acetylcholinesterase for the Treatment of Alzheimer's Disease.
    Kumar B, Dwivedi AR, Sarkar B, Gupta SK, Krishnamurthy S, Mantha AK, Parkash J, Kumar V.
    ACS Chem Neurosci; 2019 Jan 16; 10(1):252-265. PubMed ID: 30296051
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  • 28. Donepezil-like multifunctional agents: Design, synthesis, molecular modeling and biological evaluation.
    Wu MY, Esteban G, Brogi S, Shionoya M, Wang L, Campiani G, Unzeta M, Inokuchi T, Butini S, Marco-Contelles J.
    Eur J Med Chem; 2016 Oct 04; 121():864-879. PubMed ID: 26471320
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  • 29. Design, Synthesis and in vitro Evaluation of Indolotacrine Analogues as Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease.
    Benek O, Soukup O, Pasdiorova M, Hroch L, Sepsova V, Jost P, Hrabinova M, Jun D, Kuca K, Zala D, Ramsay RR, Marco-Contelles J, Musilek K.
    ChemMedChem; 2016 Jun 20; 11(12):1264-9. PubMed ID: 26427608
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  • 30. Novel dual inhibitors of AChE and MAO derived from hydroxy aminoindan and phenethylamine as potential treatment for Alzheimer's disease.
    Sterling J, Herzig Y, Goren T, Finkelstein N, Lerner D, Goldenberg W, Miskolczi I, Molnar S, Rantal F, Tamas T, Toth G, Zagyva A, Zekany A, Finberg J, Lavian G, Gross A, Friedman R, Razin M, Huang W, Krais B, Chorev M, Youdim MB, Weinstock M.
    J Med Chem; 2002 Nov 21; 45(24):5260-79. PubMed ID: 12431053
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  • 31. Synthesis, pharmacological assessment, and molecular modeling of 6-chloro-pyridonepezils: new dual AChE inhibitors as potential drugs for the treatment of Alzheimer's disease.
    Samadi A, de la Fuente Revenga M, Pérez C, Iriepa I, Moraleda I, Rodríguez-Franco MI, Marco-Contelles J.
    Eur J Med Chem; 2013 Sep 21; 67():64-74. PubMed ID: 23838422
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  • 32. Research and development of donepezil hydrochloride, a new type of acetylcholinesterase inhibitor.
    Sugimoto H, Ogura H, Arai Y, Limura Y, Yamanishi Y.
    Jpn J Pharmacol; 2002 May 21; 89(1):7-20. PubMed ID: 12083745
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  • 33. Design, synthesis and biological activity of novel donepezil derivatives bearing N-benzyl pyridinium moiety as potent and dual binding site acetylcholinesterase inhibitors.
    Lan JS, Zhang T, Liu Y, Yang J, Xie SS, Liu J, Miao ZY, Ding Y.
    Eur J Med Chem; 2017 Jun 16; 133():184-196. PubMed ID: 28388521
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  • 34. Molecular modeling, docking and ADMET studies applied to the design of a novel hybrid for treatment of Alzheimer's disease.
    da Silva CH, Campo VL, Carvalho I, Taft CA.
    J Mol Graph Model; 2006 Oct 16; 25(2):169-75. PubMed ID: 16413803
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  • 35. Synthesis, pharmacology and molecular docking on multifunctional tacrine-ferulic acid hybrids as cholinesterase inhibitors against Alzheimer's disease.
    Zhu J, Yang H, Chen Y, Lin H, Li Q, Mo J, Bian Y, Pei Y, Sun H.
    J Enzyme Inhib Med Chem; 2018 Dec 16; 33(1):496-506. PubMed ID: 29405075
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  • 36. Rational design of new multitarget histamine H3 receptor ligands as potential candidates for treatment of Alzheimer's disease.
    Łażewska D, Bajda M, Kaleta M, Zaręba P, Doroz-Płonka A, Siwek A, Alachkar A, Mogilski S, Saad A, Kuder K, Olejarz-Maciej A, Godyń J, Stary D, Sudoł S, Więcek M, Latacz G, Walczak M, Handzlik J, Sadek B, Malawska B, Kieć-Kononowicz K.
    Eur J Med Chem; 2020 Dec 01; 207():112743. PubMed ID: 32882609
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  • 37. Ethyl Acetohydroxamate Incorporated Chalcones: Unveiling a Novel Class of Chalcones for Multitarget Monoamine Oxidase-B Inhibitors Against Alzheimer's Disease.
    Reeta, Baek SC, Lee JP, Rangarajan TM, Ayushee, Singh RP, Singh M, Mangiatordi GF, Nicolotti O, Kim H, Mathew B.
    CNS Neurol Disord Drug Targets; 2019 Dec 01; 18(8):643-654. PubMed ID: 31550216
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  • 38. Chromone and donepezil hybrids as new multipotent cholinesterase and monoamine oxidase inhibitors for the potential treatment of Alzheimer's disease.
    Wang XB, Yin FC, Huang M, Jiang N, Lan JS, Kong LY.
    RSC Med Chem; 2020 Feb 01; 11(2):225-233. PubMed ID: 33479629
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  • 39. Phenoxyethyl Piperidine/Morpholine Derivatives as PAS and CAS Inhibitors of Cholinesterases: Insights for Future Drug Design.
    Pourshojaei Y, Abiri A, Eskandari K, Haghighijoo Z, Edraki N, Asadipour A.
    Sci Rep; 2019 Dec 27; 9(1):19855. PubMed ID: 31882733
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  • 40. Novel pyridazinone derivatives as butyrylcholinesterase inhibitors.
    Dundar Y, Kuyrukcu O, Eren G, Senol Deniz FS, Onkol T, Orhan IE.
    Bioorg Chem; 2019 Nov 27; 92():103304. PubMed ID: 31561108
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