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Journal Abstract Search

202 related items for PubMed ID: 25389450

  • 1. The Rac Inhibitor EHop-016 Inhibits Mammary Tumor Growth and Metastasis in a Nude Mouse Model.
    Castillo-Pichardo L, Humphries-Bickley T, De La Parra C, Forestier-Roman I, Martinez-Ferrer M, Hernandez E, Vlaar C, Ferrer-Acosta Y, Washington AV, Cubano LA, Rodriguez-Orengo J, Dharmawardhane S.
    Transl Oncol; 2014 Oct; 7(5):546-55. PubMed ID: 25389450
    [Abstract] [Full Text] [Related]

  • 2. Development of EHop-016: a small molecule inhibitor of Rac.
    Dharmawardhane S, Hernandez E, Vlaar C.
    Enzymes; 2013 Oct; 33 Pt A(Pt A):117-46. PubMed ID: 25033803
    [Abstract] [Full Text] [Related]

  • 3. Characterization of EHop-016, novel small molecule inhibitor of Rac GTPase.
    Montalvo-Ortiz BL, Castillo-Pichardo L, Hernández E, Humphries-Bickley T, De la Mota-Peynado A, Cubano LA, Vlaar CP, Dharmawardhane S.
    J Biol Chem; 2012 Apr 13; 287(16):13228-38. PubMed ID: 22383527
    [Abstract] [Full Text] [Related]

  • 4. Rac and Cdc42 inhibitors reduce macrophage function in breast cancer preclinical models.
    Torres-Sanchez A, Rivera-Robles M, Castillo-Pichardo L, Martínez-Ferrer M, Dorta-Estremera SM, Dharmawardhane S.
    Front Oncol; 2023 Apr 13; 13():1152458. PubMed ID: 37397366
    [Abstract] [Full Text] [Related]

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  • 6. Characterization of a Dual Rac/Cdc42 Inhibitor MBQ-167 in Metastatic Cancer.
    Humphries-Bickley T, Castillo-Pichardo L, Hernandez-O'Farrill E, Borrero-Garcia LD, Forestier-Roman I, Gerena Y, Blanco M, Rivera-Robles MJ, Rodriguez-Medina JR, Cubano LA, Vlaar CP, Dharmawardhane S.
    Mol Cancer Ther; 2017 May 13; 16(5):805-818. PubMed ID: 28450422
    [Abstract] [Full Text] [Related]

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  • 8. The Rac inhibitor HV-107 as a potential therapeutic for metastatic breast cancer.
    Crespo GV, Ortiz J, O'Farrill EH, Vlaar CP, Inyushin M, Kucheryavykh Y, Kucheryavykh L.
    Mol Med; 2023 Jun 14; 29(1):75. PubMed ID: 37316799
    [Abstract] [Full Text] [Related]

  • 9. Two distinct mTORC2-dependent pathways converge on Rac1 to drive breast cancer metastasis.
    Morrison Joly M, Williams MM, Hicks DJ, Jones B, Sanchez V, Young CD, Sarbassov DD, Muller WJ, Brantley-Sieders D, Cook RS.
    Breast Cancer Res; 2017 Jun 30; 19(1):74. PubMed ID: 28666462
    [Abstract] [Full Text] [Related]

  • 10. Rac1 and Rac3 isoform activation is involved in the invasive and metastatic phenotype of human breast cancer cells.
    Baugher PJ, Krishnamoorthy L, Price JE, Dharmawardhane SF.
    Breast Cancer Res; 2005 Jun 30; 7(6):R965-74. PubMed ID: 16280046
    [Abstract] [Full Text] [Related]

  • 11. [Lysophosphatidic acid (LPA) stimulates invasion and metastatic colonization of ovarian cancer cells through Rac activation].
    Yu X, Zhang Y, Chen H.
    Zhonghua Zhong Liu Za Zhi; 2015 Feb 30; 37(2):95-100. PubMed ID: 25975684
    [Abstract] [Full Text] [Related]

  • 12. Rho, Rac, Pak and angiogenesis: old roles and newly identified responsibilities in endothelial cells.
    Fryer BH, Field J.
    Cancer Lett; 2005 Nov 08; 229(1):13-23. PubMed ID: 16157214
    [Abstract] [Full Text] [Related]

  • 13. Targeting Rac and Cdc42 GEFs in Metastatic Cancer.
    Maldonado MDM, Medina JI, Velazquez L, Dharmawardhane S.
    Front Cell Dev Biol; 2020 Nov 08; 8():201. PubMed ID: 32322580
    [Abstract] [Full Text] [Related]

  • 14. Recombinant PAPP-A resistant insulin-like growth factor binding protein 4 (dBP4) inhibits angiogenesis and metastasis in a murine model of breast cancer.
    Smith YE, Toomey S, Napoletano S, Kirwan G, Schadow C, Chubb AJ, Mikkelsen JH, Oxvig C, Harmey JH.
    BMC Cancer; 2018 Oct 22; 18(1):1016. PubMed ID: 30348128
    [Abstract] [Full Text] [Related]

  • 15. Verbascoside Attenuates Rac-1 and HIF-1α Signaling Cascade in Colorectal Cancer Cells.
    Seyfi D, Behzad SB, Nabiuni M, Parivar K, Tahmaseb M, Amini E.
    Anticancer Agents Med Chem; 2018 Oct 22; 18(15):2149-2155. PubMed ID: 29886834
    [Abstract] [Full Text] [Related]

  • 16. Reduced c-Met expression by an adenovirus expressing a c-Met ribozyme inhibits tumorigenic growth and lymph node metastases of PC3-LN4 prostate tumor cells in an orthotopic nude mouse model.
    Kim SJ, Johnson M, Koterba K, Herynk MH, Uehara H, Gallick GE.
    Clin Cancer Res; 2003 Nov 01; 9(14):5161-70. PubMed ID: 14613995
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  • 18. Activation of cdc42, rac, PAK, and rho-kinase in response to hepatocyte growth factor differentially regulates epithelial cell colony spreading and dissociation.
    Royal I, Lamarche-Vane N, Lamorte L, Kaibuchi K, Park M.
    Mol Biol Cell; 2000 May 01; 11(5):1709-25. PubMed ID: 10793146
    [Abstract] [Full Text] [Related]

  • 19. Suppression of distant pulmonary metastasis of MDA-MB 435 human breast carcinoma established in mammary fat pads of nude mice by retroviral-mediated TIMP-2 gene transfer.
    Lee YK, So IS, Lee SC, Lee JH, Lee CW, Kim WM, Park MK, Lee ST, Park DY, Shin DY, Park CU, Kim YS.
    J Gene Med; 2005 Feb 01; 7(2):145-57. PubMed ID: 15546163
    [Abstract] [Full Text] [Related]

  • 20. Inhibition of breast cancer growth and metastasis by a biomimetic peptide.
    Lee E, Lee SJ, Koskimaki JE, Han Z, Pandey NB, Popel AS.
    Sci Rep; 2014 Nov 20; 4():7139. PubMed ID: 25409905
    [Abstract] [Full Text] [Related]

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