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187 related items for PubMed ID: 25393473

  • 1. Zoledronic acid induces apoptosis and S-phase arrest in mesothelioma through inhibiting Rab family proteins and topoisomerase II actions.
    Okamoto S, Jiang Y, Kawamura K, Shingyoji M, Tada Y, Sekine I, Takiguchi Y, Tatsumi K, Kobayashi H, Shimada H, Hiroshima K, Tagawa M.
    Cell Death Dis; 2014 Nov 13; 5(11):e1517. PubMed ID: 25393473
    [Abstract] [Full Text] [Related]

  • 2. Zoledronic acid produces antitumor effects on mesothelioma through apoptosis and S-phase arrest in p53-independent and Ras prenylation-independent manners.
    Okamoto S, Kawamura K, Li Q, Yamanaka M, Yang S, Fukamachi T, Tada Y, Tatsumi K, Shimada H, Hiroshima K, Kobayashi H, Tagawa M.
    J Thorac Oncol; 2012 May 13; 7(5):873-82. PubMed ID: 22481236
    [Abstract] [Full Text] [Related]

  • 3. Zoledronate has an antitumor effect and induces actin rearrangement in dexamethasone-resistant myeloma cells.
    Koizumi M, Nakaseko C, Ohwada C, Takeuchi M, Ozawa S, Shimizu N, Cho R, Nishimura M, Saito Y.
    Eur J Haematol; 2007 Nov 13; 79(5):382-91. PubMed ID: 17903213
    [Abstract] [Full Text] [Related]

  • 4. A highly sensitive prenylation assay reveals in vivo effects of bisphosphonate drug on the Rab prenylome of macrophages outside the skeleton.
    Ali N, Jurczyluk J, Shay G, Tnimov Z, Alexandrov K, Munoz MA, Skinner OP, Pavlos NJ, Rogers MJ.
    Small GTPases; 2015 Oct 02; 6(4):202-11. PubMed ID: 26399387
    [Abstract] [Full Text] [Related]

  • 5. Zoledronic acid up-regulates bone sialoprotein expression in osteoblastic cells through Rho GTPase inhibition.
    Chaplet M, Detry C, Deroanne C, Fisher LW, Castronovo V, Bellahcéne A.
    Biochem J; 2004 Dec 15; 384(Pt 3):591-8. PubMed ID: 15324309
    [Abstract] [Full Text] [Related]

  • 6. Zoledronate inhibits endothelial cell adhesion, migration and survival through the suppression of multiple, prenylation-dependent signaling pathways.
    Hasmim M, Bieler G, Rüegg C.
    J Thromb Haemost; 2007 Jan 15; 5(1):166-73. PubMed ID: 17059425
    [Abstract] [Full Text] [Related]

  • 7. Selective inhibition of Rab prenylation by a phosphonocarboxylate analogue of risedronate induces apoptosis, but not S-phase arrest, in human myeloma cells.
    Roelofs AJ, Hulley PA, Meijer A, Ebetino FH, Russell RG, Shipman CM.
    Int J Cancer; 2006 Sep 15; 119(6):1254-61. PubMed ID: 16619218
    [Abstract] [Full Text] [Related]

  • 8. Zoledronic acid exerts antitumor effects in NB4 acute promyelocytic leukemia cells by inducing apoptosis and S phase arrest.
    Liu SS, Wang XP, Li XB, Liang JY, Liu LL, Lu Y, Zhong XY, Chen YX.
    Biomed Pharmacother; 2014 Oct 15; 68(8):1031-6. PubMed ID: 25312823
    [Abstract] [Full Text] [Related]

  • 9. Deciphering the signaling networks underlying simvastatin-induced apoptosis in human cancer cells: evidence for non-canonical activation of RhoA and Rac1 GTPases.
    Zhu Y, Casey PJ, Kumar AP, Pervaiz S.
    Cell Death Dis; 2013 Apr 04; 4(4):e568. PubMed ID: 23559002
    [Abstract] [Full Text] [Related]

  • 10. Zoledronic acid activates the DNA S-phase checkpoint and induces osteosarcoma cell death characterized by apoptosis-inducing factor and endonuclease-G translocation independently of p53 and retinoblastoma status.
    Ory B, Blanchard F, Battaglia S, Gouin F, Rédini F, Heymann D.
    Mol Pharmacol; 2007 Jan 04; 71(1):333-43. PubMed ID: 17050806
    [Abstract] [Full Text] [Related]

  • 11. Induction of cell death of human osteogenic sarcoma cells by zoledronic acid resembles anoikis.
    Evdokiou A, Labrinidis A, Bouralexis S, Hay S, Findlay DM.
    Bone; 2003 Aug 04; 33(2):216-28. PubMed ID: 14499355
    [Abstract] [Full Text] [Related]

  • 12. Zoledronic acid induces S-phase arrest via a DNA damage response in normal human oral keratinocytes.
    Ohnuki H, Izumi K, Terada M, Saito T, Kato H, Suzuki A, Kawano Y, Nozawa-Inoue K, Takagi R, Maeda T.
    Arch Oral Biol; 2012 Jul 04; 57(7):906-17. PubMed ID: 22172403
    [Abstract] [Full Text] [Related]

  • 13. Zoledronic acid induces cell-cycle prolongation in murine lung cancer cells by perturbing cyclin and Ras expression.
    Li YY, Chang JW, Liu YC, Wang CH, Chang HJ, Tsai MC, Su SP, Yeh KY.
    Anticancer Drugs; 2011 Jan 04; 22(1):89-98. PubMed ID: 20926944
    [Abstract] [Full Text] [Related]

  • 14. Anticancer effects of zoledronic acid against human osteosarcoma cells.
    Kubista B, Trieb K, Sevelda F, Toma C, Arrich F, Heffeter P, Elbling L, Sutterlüty H, Scotlandi K, Kotz R, Micksche M, Berger W.
    J Orthop Res; 2006 Jun 04; 24(6):1145-52. PubMed ID: 16602111
    [Abstract] [Full Text] [Related]

  • 15. Mevalonate pathway intermediates downregulate zoledronic acid-induced isopentenyl pyrophosphate and ATP analog formation in human breast cancer cells.
    Räikkönen J, Mönkkönen H, Auriola S, Mönkkönen J.
    Biochem Pharmacol; 2010 Mar 01; 79(5):777-83. PubMed ID: 19819230
    [Abstract] [Full Text] [Related]

  • 16. A combination of a DNA-chimera siRNA against PLK-1 and zoledronic acid suppresses the growth of malignant mesothelioma cells in vitro.
    Kawata E, Ashihara E, Nakagawa Y, Kiuchi T, Ogura M, Yao H, Sakai K, Tanaka R, Nagao R, Yokota A, Takeuchi M, Kimura S, Hirai H, Maekawa T.
    Cancer Lett; 2010 Aug 28; 294(2):245-53. PubMed ID: 20206440
    [Abstract] [Full Text] [Related]

  • 17. Zoledronic acid and geranylgeraniol regulate cellular behaviour and angiogenic gene expression in human gingival fibroblasts.
    Zafar S, Coates DE, Cullinan MP, Drummond BK, Milne T, Seymour GJ.
    J Oral Pathol Med; 2014 Oct 28; 43(9):711-21. PubMed ID: 24762323
    [Abstract] [Full Text] [Related]

  • 18. Impaired geranylgeranyltransferase-I regulation reduces membrane-associated Rho protein levels in aged mouse brain.
    Afshordel S, Wood WG, Igbavboa U, Muller WE, Eckert GP.
    J Neurochem; 2014 May 28; 129(4):732-42. PubMed ID: 24428713
    [Abstract] [Full Text] [Related]

  • 19. The level of ATP analog and isopentenyl pyrophosphate correlates with zoledronic acid-induced apoptosis in cancer cells in vitro.
    Mitrofan LM, Pelkonen J, Mönkkönen J.
    Bone; 2009 Dec 28; 45(6):1153-60. PubMed ID: 19699819
    [Abstract] [Full Text] [Related]

  • 20. New insights into the actions of bisphosphonate zoledronic acid in breast cancer cells by dual RhoA-dependent and -independent effects.
    Denoyelle C, Hong L, Vannier JP, Soria J, Soria C.
    Br J Cancer; 2003 May 19; 88(10):1631-40. PubMed ID: 12771933
    [Abstract] [Full Text] [Related]

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