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226 related items for PubMed ID: 25407271

  • 1. MEK1/2 inhibitor U0126 but not endothelin receptor antagonist clazosentan reduces upregulation of cerebrovascular contractile receptors and delayed cerebral ischemia, and improves outcome after subarachnoid hemorrhage in rats.
    Povlsen GK, Edvinsson L.
    J Cereb Blood Flow Metab; 2015 Feb; 35(2):329-37. PubMed ID: 25407271
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  • 5. MEK1/2 inhibitor U0126, but not nimodipine, reduces upregulation of cerebrovascular contractile receptors after subarachnoid haemorrhage in rats.
    Christensen ST, Johansson SE, Radziwon-Balicka A, Warfvinge K, Haanes KA, Edvinsson L.
    PLoS One; 2019 Feb; 14(4):e0215398. PubMed ID: 30978262
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  • 7. Microvasospasms After Experimental Subarachnoid Hemorrhage Do Not Depend on Endothelin A Receptors.
    Liu H, Dienel A, Schöller K, Schwarzmaier SM, Nehrkorn K, Plesnila N, Terpolilli NA.
    Stroke; 2018 Mar; 49(3):693-699. PubMed ID: 29438081
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  • 8. Early events triggering delayed vasoconstrictor receptor upregulation and cerebral ischemia after subarachnoid hemorrhage.
    Povlsen GK, Johansson SE, Larsen CC, Samraj AK, Edvinsson L.
    BMC Neurosci; 2013 Mar 15; 14():34. PubMed ID: 23496889
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  • 9. ERK1/2 inhibition attenuates cerebral blood flow reduction and abolishes ET(B) and 5-HT(1B) receptor upregulation after subarachnoid hemorrhage in rat.
    Beg SA, Hansen-Schwartz JA, Vikman PJ, Xu CB, Edvinsson LI.
    J Cereb Blood Flow Metab; 2006 Jun 15; 26(6):846-56. PubMed ID: 16251886
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  • 10. Rapid functional upregulation of vasocontractile endothelin ETB receptors in rat coronary arteries.
    Skovsted GF, Pedersen AF, Larsen R, Sheykhzade M, Edvinsson L.
    Life Sci; 2012 Oct 15; 91(13-14):593-9. PubMed ID: 22391414
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  • 11. Proteomic Expression Changes in Large Cerebral Arteries After Experimental Subarachnoid Hemorrhage in Rat Are Regulated by the MEK-ERK1/2 Pathway.
    Müller AH, Edwards AVG, Larsen MR, Nielsen J, Warfvinge K, Povlsen GK, Edvinsson L.
    J Mol Neurosci; 2017 Aug 15; 62(3-4):380-394. PubMed ID: 28741142
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  • 12. CaMKII inhibition with KN93 attenuates endothelin and serotonin receptor-mediated vasoconstriction and prevents subarachnoid hemorrhage-induced deficits in sensorimotor function.
    Edvinsson L, Povlsen GK, Ahnstedt H, Waldsee R.
    J Neuroinflammation; 2014 Dec 10; 11():207. PubMed ID: 25498987
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  • 14. From bench-to-bedside in catastrophic cerebrovascular disease: development of drugs targeting the endothelin axis in subarachnoid hemorrhage-related vasospasm.
    Ardelt A.
    Neurol Res; 2012 Mar 10; 34(2):195-210. PubMed ID: 22333896
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  • 15. Protein kinase C inhibition prevents upregulation of vascular ET(B) and 5-HT(1B) receptors and reverses cerebral blood flow reduction after subarachnoid haemorrhage in rats.
    Beg SS, Hansen-Schwartz JA, Vikman PJ, Xu CB, Edvinsson LI.
    J Cereb Blood Flow Metab; 2007 Jan 10; 27(1):21-32. PubMed ID: 16736053
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  • 16. Neurokinin-1 receptor antagonism in a rat model of subarachnoid hemorrhage: prevention of upregulation of contractile ETB and 5-HT1B receptors and cerebral blood flow reduction.
    Ansar S, Svendgaard NA, Edvinsson L.
    J Neurosurg; 2007 May 10; 106(5):881-6. PubMed ID: 17542534
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  • 17. Dissociation of vasospasm and secondary effects of experimental subarachnoid hemorrhage by clazosentan.
    Sabri M, Ai J, Macdonald RL.
    Stroke; 2011 May 10; 42(5):1454-60. PubMed ID: 21454820
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  • 18. Regulation of enhanced cerebrovascular expression of proinflammatory mediators in experimental subarachnoid hemorrhage via the mitogen-activated protein kinase kinase/extracellular signal-regulated kinase pathway.
    Maddahi A, Povlsen GK, Edvinsson L.
    J Neuroinflammation; 2012 Dec 21; 9():274. PubMed ID: 23259581
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  • 19. Ro 61-1790, a new hydrosoluble endothelin antagonist: general pharmacology and effects on experimental cerebral vasospasm.
    Roux S, Breu V, Giller T, Neidhart W, Ramuz H, Coassolo P, Clozel JP, Clozel M.
    J Pharmacol Exp Ther; 1997 Dec 21; 283(3):1110-8. PubMed ID: 9399983
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  • 20. Dissociation of vasospasm-related morbidity and outcomes in patients with aneurysmal subarachnoid hemorrhage treated with clazosentan: a meta-analysis of randomized controlled trials.
    Shen J, Pan JW, Fan ZX, Xiong XX, Zhan RY.
    J Neurosurg; 2013 Jul 21; 119(1):180-9. PubMed ID: 23641823
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