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Journal Abstract Search


298 related items for PubMed ID: 25424799

  • 1. Optimization and revision of the production process of the Necator americanus glutathione S-transferase 1 (Na-GST-1), the lead hookworm vaccine recombinant protein candidate.
    Curti E, Seid CA, Hudspeth E, Center L, Rezende W, Pollet J, Kwityn C, Hammond M, Matsunami RK, Engler DA, Hotez PJ, Elena Bottazzi M.
    Hum Vaccin Immunother; 2014; 10(7):1914-25. PubMed ID: 25424799
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  • 2. Expression, purification, and characterization of the Necator americanus aspartic protease-1 (Na-APR-1 (M74)) antigen, a component of the bivalent human hookworm vaccine.
    Seid CA, Curti E, Jones RM, Hudspeth E, Rezende W, Pollet J, Center L, Versteeg L, Pritchard S, Musiychuk K, Yusibov V, Hotez PJ, Bottazzi ME.
    Hum Vaccin Immunother; 2015; 11(6):1474-88. PubMed ID: 25905574
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  • 4. Molecular cloning, biochemical characterization, and partial protective immunity of the heme-binding glutathione S-transferases from the human hookworm Necator americanus.
    Zhan B, Perally S, Brophy PM, Xue J, Goud G, Liu S, Deumic V, de Oliveira LM, Bethony J, Bottazzi ME, Jiang D, Gillespie P, Xiao SH, Gupta R, Loukas A, Ranjit N, Lustigman S, Oksov Y, Hotez P.
    Infect Immun; 2010 Apr; 78(4):1552-63. PubMed ID: 20145100
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  • 5. Advances in vaccines against neglected tropical diseases: enhancing physical stability of a recombinant hookworm vaccine through biophysical and formulation studies.
    Plieskatt JL, Rezende WC, Olsen CM, Trefethen JM, Joshi SB, Middaugh CR, Hotez PJ, Bottazzi ME.
    Hum Vaccin Immunother; 2012 Jun; 8(6):765-76. PubMed ID: 22495115
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  • 8. The evaluation of recombinant hookworm antigens as vaccines in hamsters (Mesocricetus auratus) challenged with human hookworm, Necator americanus.
    Xiao S, Zhan B, Xue J, Goud GN, Loukas A, Liu Y, Williamson A, Liu S, Deumic V, Hotez P.
    Exp Parasitol; 2008 Jan; 118(1):32-40. PubMed ID: 17645877
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  • 9. Safety and immunogenicity of the co-administered Na-APR-1 and Na-GST-1 hookworm vaccines in school-aged children in Gabon: a randomised, controlled, observer-blind, phase 1, dose-escalation trial.
    Zinsou JF, Diemert DJ, Dejon-Agobé JC, Adégbité BR, Honkpehedji YJ, Vodonou KG, Bikangui R, Edoa JR, Massinga Loembe M, Li G, Yazdanbakhsh M, Bottazzi ME, van Leeuwen R, Kremsner PG, Hotez PJ, Bethony JM, Grobusch MP, Adegnika AA.
    Lancet Infect Dis; 2024 Jul; 24(7):760-774. PubMed ID: 38513684
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  • 11. Expression of the Necator americanus hookworm larval antigen Na-ASP-2 in Pichia pastoris and purification of the recombinant protein for use in human clinical trials.
    Goud GN, Bottazzi ME, Zhan B, Mendez S, Deumic V, Plieskatt J, Liu S, Wang Y, Bueno L, Fujiwara R, Samuel A, Ahn SY, Solanki M, Asojo OA, Wang J, Bethony JM, Loukas A, Roy M, Hotez PJ.
    Vaccine; 2005 Sep 15; 23(39):4754-64. PubMed ID: 16054275
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  • 13. Structure of monomeric Na-GST-3, a glutathione S-transferase from the major human hookworm parasite Necator americanus.
    Kelleher A, Zhan B, Asojo OA.
    Acta Crystallogr Sect F Struct Biol Cryst Commun; 2013 Aug 15; 69(Pt 8):839-43. PubMed ID: 23908024
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  • 16. Fusion of Na-ASP-2 with human immunoglobulin Fcγ abrogates histamine release from basophils sensitized with anti-Na-ASP-2 IgE.
    Zhan B, Santiago H, Keegan B, Gillespie P, Xue J, Bethony J, de Oliveira LM, Jiang D, Diemert D, Xiao SH, Jones K, Feng X, Hotez PJ, Bottazzi ME.
    Parasite Immunol; 2012 Aug 15; 34(8-9):404-11. PubMed ID: 22651670
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  • 20. A family of cathepsin B cysteine proteases expressed in the gut of the human hookworm, Necator americanus.
    Ranjit N, Zhan B, Stenzel DJ, Mulvenna J, Fujiwara R, Hotez PJ, Loukas A.
    Mol Biochem Parasitol; 2008 Aug 15; 160(2):90-9. PubMed ID: 18501979
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