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632 related items for PubMed ID: 25425963

  • 1. Klf5 deletion promotes Pten deletion-initiated luminal-type mouse prostate tumors through multiple oncogenic signaling pathways.
    Xing C, Ci X, Sun X, Fu X, Zhang Z, Dong EN, Hao ZZ, Dong JT.
    Neoplasia; 2014 Nov; 16(11):883-99. PubMed ID: 25425963
    [Abstract] [Full Text] [Related]

  • 2. Additive Effect of Zfhx3/Atbf1 and Pten Deletion on Mouse Prostatic Tumorigenesis.
    Sun X, Xing C, Fu X, Li J, Zhang B, Frierson HF, Dong JT.
    J Genet Genomics; 2015 Jul 20; 42(7):373-82. PubMed ID: 26233892
    [Abstract] [Full Text] [Related]

  • 3. KLF5 inhibits angiogenesis in PTEN-deficient prostate cancer by attenuating AKT activation and subsequent HIF1α accumulation.
    Ci X, Xing C, Zhang B, Zhang Z, Ni JJ, Zhou W, Dong JT.
    Mol Cancer; 2015 Apr 21; 14():91. PubMed ID: 25896712
    [Abstract] [Full Text] [Related]

  • 4. Conditional deletion of the Pten gene in the mouse prostate induces prostatic intraepithelial neoplasms at early ages but a slow progression to prostate tumors.
    Kwak MK, Johnson DT, Zhu C, Lee SH, Ye DW, Luong R, Sun Z.
    PLoS One; 2013 Apr 21; 8(1):e53476. PubMed ID: 23308230
    [Abstract] [Full Text] [Related]

  • 5. Interruption of KLF5 acetylation promotes PTEN-deficient prostate cancer progression by reprogramming cancer-associated fibroblasts.
    Zhang B, Liu M, Mai F, Li X, Wang W, Huang Q, Du X, Ding W, Li Y, Barwick BG, Ni JJ, Osunkoya AO, Chen Y, Zhou W, Xia S, Dong JT.
    J Clin Invest; 2024 May 23; 134(14):. PubMed ID: 38781024
    [Abstract] [Full Text] [Related]

  • 6. KLF5 is frequently deleted and down-regulated but rarely mutated in prostate cancer.
    Chen C, Bhalala HV, Vessella RL, Dong JT.
    Prostate; 2003 May 01; 55(2):81-8. PubMed ID: 12661032
    [Abstract] [Full Text] [Related]

  • 7. Targeted biallelic inactivation of Pten in the mouse prostate leads to prostate cancer accompanied by increased epithelial cell proliferation but not by reduced apoptosis.
    Ma X, Ziel-van der Made AC, Autar B, van der Korput HA, Vermeij M, van Duijn P, Cleutjens KB, de Krijger R, Krimpenfort P, Berns A, van der Kwast TH, Trapman J.
    Cancer Res; 2005 Jul 01; 65(13):5730-9. PubMed ID: 15994948
    [Abstract] [Full Text] [Related]

  • 8. Krüppel-like factor 5 promotes apoptosis triggered by tumor necrosis factor α in LNCaP prostate cancer cells via up-regulation of mitogen-activated protein kinase kinase 7.
    Shi Q, Gao Y, Xu S, Du C, Li F, Tang XS, Jia J, Wang X, Chang L, He D, Guo P.
    Urol Oncol; 2016 Feb 01; 34(2):58.e11-8. PubMed ID: 26480897
    [Abstract] [Full Text] [Related]

  • 9. NFATc1 promotes prostate tumorigenesis and overcomes PTEN loss-induced senescence.
    Manda KR, Tripathi P, Hsi AC, Ning J, Ruzinova MB, Liapis H, Bailey M, Zhang H, Maher CA, Humphrey PA, Andriole GL, Ding L, You Z, Chen F.
    Oncogene; 2016 Jun 23; 35(25):3282-92. PubMed ID: 26477312
    [Abstract] [Full Text] [Related]

  • 10. Deletion of atbf1/zfhx3 in mouse prostate causes neoplastic lesions, likely by attenuation of membrane and secretory proteins and multiple signaling pathways.
    Sun X, Fu X, Li J, Xing C, Frierson HF, Wu H, Ding X, Ju T, Cummings RD, Dong JT.
    Neoplasia; 2014 May 23; 16(5):377-89. PubMed ID: 24934715
    [Abstract] [Full Text] [Related]

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  • 12. Activation of hepatocyte growth factor/MET signaling initiates oncogenic transformation and enhances tumor aggressiveness in the murine prostate.
    Mi J, Hooker E, Balog S, Zeng H, Johnson DT, He Y, Yu EJ, Wu H, Le V, Lee DH, Aldahl J, Gonzalgo ML, Sun Z.
    J Biol Chem; 2018 Dec 28; 293(52):20123-20136. PubMed ID: 30401749
    [Abstract] [Full Text] [Related]

  • 13. SLUG is a direct transcriptional repressor of PTEN tumor suppressor.
    Uygur B, Abramo K, Leikina E, Vary C, Liaw L, Wu WS.
    Prostate; 2015 Jun 15; 75(9):907-16. PubMed ID: 25728608
    [Abstract] [Full Text] [Related]

  • 14. Loss of Nkx3.1 leads to the activation of discrete downstream target genes during prostate tumorigenesis.
    Song H, Zhang B, Watson MA, Humphrey PA, Lim H, Milbrandt J.
    Oncogene; 2009 Sep 17; 28(37):3307-19. PubMed ID: 19597465
    [Abstract] [Full Text] [Related]

  • 15. PTEN deficiency is fully penetrant for prostate adenocarcinoma in C57BL/6 mice via mTOR-dependent growth.
    Blando J, Portis M, Benavides F, Alexander A, Mills G, Dave B, Conti CJ, Kim J, Walker CL.
    Am J Pathol; 2009 May 17; 174(5):1869-79. PubMed ID: 19395652
    [Abstract] [Full Text] [Related]

  • 16. Cytosolic phospholipase A2α sustains pAKT, pERK and AR levels in PTEN-null/mutated prostate cancer cells.
    Hua S, Yao M, Vignarajan S, Witting P, Hejazi L, Gong Z, Teng Y, Niknami M, Assinder S, Richardson D, Dong Q.
    Biochim Biophys Acta; 2013 Jun 17; 1831(6):1146-57. PubMed ID: 23500889
    [Abstract] [Full Text] [Related]

  • 17. KLF5 promotes cell proliferation and tumorigenesis through gene regulation and the TSU-Pr1 human bladder cancer cell line.
    Chen C, Benjamin MS, Sun X, Otto KB, Guo P, Dong XY, Bao Y, Zhou Z, Cheng X, Simons JW, Dong JT.
    Int J Cancer; 2006 Mar 15; 118(6):1346-55. PubMed ID: 16184550
    [Abstract] [Full Text] [Related]

  • 18. Posttranslational regulation of membrane type 1-matrix metalloproteinase (MT1-MMP) in mouse PTEN null prostate cancer cells: Enhanced surface expression and differential O-glycosylation of MT1-MMP.
    Kim S, Huang W, Mottillo EP, Sohail A, Ham YA, Conley-Lacomb MK, Kim CJ, Tzivion G, Kim HR, Wang S, Chen YQ, Fridman R.
    Biochim Biophys Acta; 2010 Nov 15; 1803(11):1287-97. PubMed ID: 20620173
    [Abstract] [Full Text] [Related]

  • 19. Regulation of KLF5 involves the Sp1 transcription factor in human epithelial cells.
    Chen C, Zhou Y, Zhou Z, Sun X, Otto KB, Uht RM, Dong JT.
    Gene; 2004 Apr 14; 330():133-42. PubMed ID: 15087132
    [Abstract] [Full Text] [Related]

  • 20. LZTS2 and PTEN collaboratively regulate ß-catenin in prostatic tumorigenesis.
    Yu EJ, Hooker E, Johnson DT, Kwak MK, Zou K, Luong R, He Y, Sun Z.
    PLoS One; 2017 Apr 14; 12(3):e0174357. PubMed ID: 28323888
    [Abstract] [Full Text] [Related]

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