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371 related items for PubMed ID: 25441457

  • 1. Thiopurine dose intensity and treatment outcome in childhood lymphoblastic leukaemia: the influence of thiopurine methyltransferase pharmacogenetics.
    Lennard L, Cartwright CS, Wade R, Vora A.
    Br J Haematol; 2015 Apr; 169(2):228-40. PubMed ID: 25441457
    [Abstract] [Full Text] [Related]

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  • 3. Thiopurine S-methyltransferase (TPMT) polymorphisms in children with acute lymphoblastic leukemia, and the need for reduction or cessation of 6-mercaptopurine doses during maintenance therapy: the Polish multicenter analysis.
    Peregud-Pogorzelski J, Tetera-Rudnicka E, Kurzawski M, Brodkiewicz A, Adrianowska N, Mlynarski W, Januszkiewicz D, Drozdzik M.
    Pediatr Blood Cancer; 2011 Oct; 57(4):578-82. PubMed ID: 21319286
    [Abstract] [Full Text] [Related]

  • 4. Thiopurine methyltransferase (TPMT) genotype and early treatment response to mercaptopurine in childhood acute lymphoblastic leukemia.
    Stanulla M, Schaeffeler E, Flohr T, Cario G, Schrauder A, Zimmermann M, Welte K, Ludwig WD, Bartram CR, Zanger UM, Eichelbaum M, Schrappe M, Schwab M.
    JAMA; 2005 Mar 23; 293(12):1485-9. PubMed ID: 15784872
    [Abstract] [Full Text] [Related]

  • 5. Thiopurine methyltransferase genotype-phenotype discordance and thiopurine active metabolite formation in childhood acute lymphoblastic leukaemia.
    Lennard L, Cartwright CS, Wade R, Richards SM, Vora A.
    Br J Clin Pharmacol; 2013 Jul 23; 76(1):125-36. PubMed ID: 23252716
    [Abstract] [Full Text] [Related]

  • 6. Thiopurine S-methyltransferase gene polymorphism and 6-mercaptopurine dose intensity in Indian children with acute lymphoblastic leukemia.
    Kapoor G, Sinha R, Naithani R, Chandgothia M.
    Leuk Res; 2010 Aug 23; 34(8):1023-6. PubMed ID: 20153897
    [Abstract] [Full Text] [Related]

  • 7. Thiopurine S-methyltransferase phenotype-genotype correlation in children with acute lymphoblastic leukemia.
    Chrzanowska M, Kuehn M, Januszkiewicz-Lewandowska D, Kurzawski M, Droździk M.
    Acta Pol Pharm; 2012 Aug 23; 69(3):405-10. PubMed ID: 22594254
    [Abstract] [Full Text] [Related]

  • 8. Pharmacogenetics of 6-mercaptopurine in a black Zimbabwean cohort treated for acute lymphoblastic leukaemia.
    Chikondowa P, Munkombwe D, Chikwambi Z, Kuona P, Masimirembwa C.
    Pharmacogenomics; 2023 Jun 23; 24(8):449-457. PubMed ID: 37248698
    [Abstract] [Full Text] [Related]

  • 9. Thiopurine methyltransferase activity is related to the risk of relapse of childhood acute lymphoblastic leukemia: results from the NOPHO ALL-92 study.
    Schmiegelow K, Forestier E, Kristinsson J, Söderhäll S, Vettenranta K, Weinshilboum R, Wesenberg F, Nordic Society of Paediatric Haematology and Oncology.
    Leukemia; 2009 Mar 23; 23(3):557-64. PubMed ID: 18987654
    [Abstract] [Full Text] [Related]

  • 10. Individualization of thiopurine therapy: thiopurine S-methyltransferase and beyond.
    Karas-Kuzelicki N, Mlinaric-Rascan I.
    Pharmacogenomics; 2009 Aug 23; 10(8):1309-22. PubMed ID: 19663675
    [Abstract] [Full Text] [Related]

  • 11. Thiopurine S-methyltransferase (TPMT) gene polymorphism in Brazilian children with acute lymphoblastic leukemia: association with clinical and laboratory data.
    Silva MR, de Oliveira BM, Viana MB, Murao M, Romanha AJ.
    Ther Drug Monit; 2008 Dec 23; 30(6):700-4. PubMed ID: 19057372
    [Abstract] [Full Text] [Related]

  • 12. Pharmacogenetically based dosing of thiopurines in childhood acute lymphoblastic leukemia: influence on cure rates and risk of second cancer.
    Levinsen M, Rotevatn EØ, Rosthøj S, Nersting J, Abrahamsson J, Appell ML, Bergan S, Bechensteen AG, Harila-Saari A, Heyman M, Jonsson OG, Maxild JB, Niemi M, Söderhäll S, Schmiegelow K, Nordic Society of Paediatric Haematology, Oncology.
    Pediatr Blood Cancer; 2014 May 23; 61(5):797-802. PubMed ID: 24395436
    [Abstract] [Full Text] [Related]

  • 13. [Importance of genotyping of thiopurine S-methyltransferase in children with acute lymphoblastic leukaemia during maintenance therapy].
    Dokmanović L, Janić D, Krstovski N, Zukić B, Tosić N, Pavlović S.
    Srp Arh Celok Lek; 2008 May 23; 136(11-12):609-16. PubMed ID: 19177822
    [Abstract] [Full Text] [Related]

  • 14. Analysis of thiopurine S-methyltransferase polymorphism in the population of Serbia and Montenegro and mercaptopurine therapy tolerance in childhood acute lymphoblastic leukemia.
    Dokmanovic L, Urosevic J, Janic D, Jovanovic N, Petrucev B, Tosic N, Pavlovic S.
    Ther Drug Monit; 2006 Dec 23; 28(6):800-6. PubMed ID: 17164697
    [Abstract] [Full Text] [Related]

  • 15. The thiopurine methyltransferase genetic polymorphism is associated with thioguanine-related veno-occlusive disease of the liver in children with acute lymphoblastic leukemia.
    Lennard L, Richards S, Cartwright CS, Mitchell C, Lilleyman JS, Vora A, UK MRC/NCRI Childhood Leukaemia Working Party.
    Clin Pharmacol Ther; 2006 Oct 23; 80(4):375-83. PubMed ID: 17015055
    [Abstract] [Full Text] [Related]

  • 16. Mercaptopurine therapy intolerance and heterozygosity at the thiopurine S-methyltransferase gene locus.
    Relling MV, Hancock ML, Rivera GK, Sandlund JT, Ribeiro RC, Krynetski EY, Pui CH, Evans WE.
    J Natl Cancer Inst; 1999 Dec 01; 91(23):2001-8. PubMed ID: 10580024
    [Abstract] [Full Text] [Related]

  • 17. Should TPMT genotype and activity be used to monitor 6-mercaptopurine treatment in children with acute lymphoblastic leukaemia?
    Fakhoury M, Andreu-Gallien J, Mahr A, Medard Y, Azougagh S, Vilmer E, Jacqz-Aigrain E.
    J Clin Pharm Ther; 2007 Dec 01; 32(6):633-9. PubMed ID: 18021342
    [Abstract] [Full Text] [Related]

  • 18. No association between relapse hazard and thiopurine methyltransferase geno- or phenotypes in non-high risk acute lymphoblastic leukemia: a NOPHO ALL2008 sub-study.
    Nielsen SN, Toksvang LN, Grell K, Nersting J, Abrahamsson J, Lund B, Kanerva J, Jónsson ÓG, Vaitkeviciene G, Pruunsild K, Appell ML, Hjalgrim LL, Schmiegelow K.
    Cancer Chemother Pharmacol; 2021 Aug 01; 88(2):271-279. PubMed ID: 33928426
    [Abstract] [Full Text] [Related]

  • 19. Thiopurine methyltransferase polymorphisms and mercaptopurine tolerance in Turkish children with acute lymphoblastic leukemia.
    Albayrak M, Konyssova U, Kaya Z, Gursel T, Guntekin S, Percin EF, Kocak U.
    Cancer Chemother Pharmacol; 2011 Nov 01; 68(5):1155-9. PubMed ID: 21400026
    [Abstract] [Full Text] [Related]

  • 20. Prognostic importance of 6-mercaptopurine dose intensity in acute lymphoblastic leukemia.
    Relling MV, Hancock ML, Boyett JM, Pui CH, Evans WE.
    Blood; 1999 May 01; 93(9):2817-23. PubMed ID: 10216075
    [Abstract] [Full Text] [Related]

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