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263 related items for PubMed ID: 25446499

  • 1. 4'-Demethyl-deoxypodophyllotoxin glucoside isolated from Podophyllum hexandrum exhibits potential anticancer activities by altering Chk-2 signaling pathway in MCF-7 breast cancer cells.
    Zilla MK, Nayak D, Amin H, Nalli Y, Rah B, Chakraborty S, Kitchlu S, Goswami A, Ali A.
    Chem Biol Interact; 2014 Dec 05; 224():100-7. PubMed ID: 25446499
    [Abstract] [Full Text] [Related]

  • 2. Apoptosis induced by one new podophyllotoxin glucoside in human carcinoma cells.
    Zhang QY, Jiang M, Zhao CQ, Yu M, Zhang H, Ding YJ, Zhai YG.
    Toxicology; 2005 Aug 15; 212(1):46-53. PubMed ID: 15923073
    [Abstract] [Full Text] [Related]

  • 3. Three new cytotoxic aryltetralin lignans from Sinopodophyllum emodi.
    Sun YJ, Li ZL, Chen H, Liu XQ, Zhou W, Hua HM.
    Bioorg Med Chem Lett; 2011 Jun 15; 21(12):3794-7. PubMed ID: 21570846
    [Abstract] [Full Text] [Related]

  • 4. Cytotoxicity and apoptosis induced by a new podophyllotoxin glucoside in human hepatoma (HepG2) cells.
    Liu Y, Zhao C, Li H, Yu M, Gao J, Wang L, Zhai Y.
    Can J Physiol Pharmacol; 2010 Apr 15; 88(4):472-9. PubMed ID: 20555416
    [Abstract] [Full Text] [Related]

  • 5. Two new podophyllotoxin glucosides from Sinopodophyllum emodi (Wall.) Ying.
    Zhao C, Huang J, Nagatsu A, Ogihara Y.
    Chem Pharm Bull (Tokyo); 2001 Jun 15; 49(6):773-5. PubMed ID: 11411537
    [Abstract] [Full Text] [Related]

  • 6. SAR analysis and biological studies of synthesized podophyllum derivates obtained by N linkage modification at C-4 position.
    Wang H, Tang L, Tang Y, Yuan Z.
    Bioorg Med Chem; 2014 Nov 01; 22(21):6183-92. PubMed ID: 25282651
    [Abstract] [Full Text] [Related]

  • 7. Deoxypodophyllotoxin induces G2/M cell cycle arrest and apoptosis in HeLa cells.
    Shin SY, Yong Y, Kim CG, Lee YH, Lim Y.
    Cancer Lett; 2010 Jan 28; 287(2):231-9. PubMed ID: 19616373
    [Abstract] [Full Text] [Related]

  • 8. Comparison of carbon-sulfur and carbon-amine bond in therapeutic drug: 4β-S-aromatic heterocyclic podophyllum derivatives display antitumor activity.
    Li JL, Zhao W, Zhou C, Zhang YX, Li HM, Tang YL, Liang XH, Chen T, Tang YJ.
    Sci Rep; 2015 Oct 07; 5():14814. PubMed ID: 26443888
    [Abstract] [Full Text] [Related]

  • 9. Quercetin-6-C-β-D-glucopyranoside, natural analog of quercetin exhibits anti-prostate cancer activity by inhibiting Akt-mTOR pathway via aryl hydrocarbon receptor.
    Hamidullah, Kumar R, Saini KS, Kumar A, Kumar S, Ramakrishna E, Maurya R, Konwar R, Chattopadhyay N.
    Biochimie; 2015 Dec 07; 119():68-79. PubMed ID: 26476001
    [Abstract] [Full Text] [Related]

  • 10. Inhibition of Twist1-mediated invasion by Chk2 promotes premature senescence in p53-defective cancer cells.
    Nayak D, Kumar A, Chakraborty S, Rasool RU, Amin H, Katoch A, Gopinath V, Mahajan V, Zilla MK, Rah B, Gandhi SG, Ali A, Kumar LD, Goswami A.
    Cell Death Differ; 2017 Jul 07; 24(7):1275-1287. PubMed ID: 28498365
    [Abstract] [Full Text] [Related]

  • 11. Synthesis and evaluation of the cell cycle arrest and CT DNA interaction properties of 4β-amino-4'-O-demethyl-4-deoxypodophyllotoxins.
    Liu JF, Sang CY, Qin WW, Zhao J, Hui L, Ding YL, Chen SW.
    Bioorg Med Chem; 2013 Nov 15; 21(22):6948-55. PubMed ID: 24095019
    [Abstract] [Full Text] [Related]

  • 12. Investigation of the Lignan Content in Extracts from Linum, Callitris and Juniperus Species in Relation to Their In Vitro Antiproliferative Activities.
    Doussot J, Mathieu V, Colas C, Molinié R, Corbin C, Montguillon J, Moreno Y Banuls L, Renouard S, Lamblin F, Dupré P, Maunit B, Kiss R, Hano C, Lainé E.
    Planta Med; 2017 Apr 15; 83(6):574-581. PubMed ID: 27776375
    [Abstract] [Full Text] [Related]

  • 13. Antineoplastic Agents. 585. Isolation of Bridelia ferruginea Anticancer Podophyllotoxins and Synthesis of 4-Aza-podophyllotoxin Structural Modifications.
    Pettit GR, Searcy JD, Tan R, Cragg GM, Melody N, Knight JC, Chapuis JC.
    J Nat Prod; 2016 Mar 25; 79(3):507-18. PubMed ID: 26938998
    [Abstract] [Full Text] [Related]

  • 14. Design and synthesis of novel 4'-demethyl-4-deoxypodophyllotoxin derivatives as potential anticancer agents.
    Zhu X, Fu J, Tang Y, Gao Y, Zhang S, Guo Q.
    Bioorg Med Chem Lett; 2016 Feb 15; 26(4):1360-4. PubMed ID: 26804229
    [Abstract] [Full Text] [Related]

  • 15. Countering effects of a combination of podophyllotoxin, podophyllotoxin β-D-glucoside and rutin hydrate in minimizing radiation induced chromosomal damage, ROS and apoptosis in human blood lymphocytes.
    Dutta S, Yashavarddhan MH, Srivastava NN, Ranjan R, Bajaj S, Kalita B, Singh A, Flora SJ, Gupta ML.
    Food Chem Toxicol; 2016 May 15; 91():141-50. PubMed ID: 26993954
    [Abstract] [Full Text] [Related]

  • 16. Cytotoxicity, apoptosis induction, and mitotic arrest by a novel podophyllotoxin glucoside, 4DPG, in tumor cells.
    Qi YL, Liao F, Zhao CQ, Lin YD, Zuo MX.
    Acta Pharmacol Sin; 2005 Aug 15; 26(8):1000-8. PubMed ID: 16038635
    [Abstract] [Full Text] [Related]

  • 17. Characterization of two epimers, 4alpha and 4beta, of a novel podophyllotoxin-4-O-(D)-6-acetylglucopyranoside from Podophyllum hexandrum by LC-ESI-MS-MS.
    Puri SC, Handa G, Bhat BA, Dhar KL, Spiteller M, Qazi GN.
    J Chromatogr Sci; 2006 Aug 15; 44(5):239-43. PubMed ID: 16774707
    [Abstract] [Full Text] [Related]

  • 18. Cytotoxicity of in vitro produced podophyllotoxin from Podophyllum hexandrum on human cancer cell line.
    Chattopadhyay S, Bisaria VS, Panda AK, Srivastava AK.
    Nat Prod Res; 2004 Feb 15; 18(1):51-7. PubMed ID: 14974618
    [Abstract] [Full Text] [Related]

  • 19. Carbamates of 4'-demethyl-4-deoxypodophyllotoxin: synthesis, cytotoxicity and cell cycle effects.
    Chen SW, Gao YY, Zhou NN, Liu J, Huang WT, Hui L, Jin Y, Jin YX.
    Bioorg Med Chem Lett; 2011 Dec 15; 21(24):7355-8. PubMed ID: 22041063
    [Abstract] [Full Text] [Related]

  • 20. Chemometric evaluation of the anti-cancer pro-drug podophyllotoxin and potential therapeutic analogues in Juniperus and Podophyllum species.
    Kusari S, Zühlke S, Spiteller M.
    Phytochem Anal; 2011 Dec 15; 22(2):128-43. PubMed ID: 21046682
    [Abstract] [Full Text] [Related]

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