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152 related items for PubMed ID: 2544721

  • 1. Synthesis of 3-deazaneplanocin A, a powerful inhibitor of S-adenosylhomocysteine hydrolase with potent and selective in vitro and in vivo antiviral activities.
    Tseng CK, Marquez VE, Fuller RW, Goldstein BM, Haines DR, McPherson H, Parsons JL, Shannon WM, Arnett G, Hollingshead M.
    J Med Chem; 1989 Jul; 32(7):1442-6. PubMed ID: 2544721
    [Abstract] [Full Text] [Related]

  • 2. New neplanocin analogues. 7. Synthesis and antiviral activity of 2-halo derivatives of neplanocin A.
    Obara T, Shuto S, Saito Y, Snoeck R, Andrei G, Balzarini J, De Clercq E, Matsuda A.
    J Med Chem; 1996 Sep 13; 39(19):3847-52. PubMed ID: 8809173
    [Abstract] [Full Text] [Related]

  • 3. New neplanocin analogues. 6. Synthesis and potent antiviral activity of 6'-homoneplanocin A1.
    Shuto S, Obara T, Saito Y, Andrei G, Snoeck R, De Clercq E, Matsuda A.
    J Med Chem; 1996 Jun 07; 39(12):2392-9. PubMed ID: 8691433
    [Abstract] [Full Text] [Related]

  • 4. Broad-spectrum antiviral activities of neplanocin A, 3-deazaneplanocin A, and their 5'-nor derivatives.
    De Clercq E, Cools M, Balzarini J, Marquez VE, Borcherding DR, Borchardt RT, Drach JC, Kitaoka S, Konno T.
    Antimicrob Agents Chemother; 1989 Aug 07; 33(8):1291-7. PubMed ID: 2552906
    [Abstract] [Full Text] [Related]

  • 5. Correlation between the antiviral activity of acyclic and carbocyclic adenosine analogues in murine L929 cells and their inhibitory effect on L929 cells S-adenosylhomocysteine hydrolase.
    Cools M, de Clercq E.
    Biochem Pharmacol; 1989 Apr 01; 38(7):1061-7. PubMed ID: 2539815
    [Abstract] [Full Text] [Related]

  • 6. Synthesis and antiviral evaluation of 6'-substituted aristeromycins: potential mechanism-based inhibitors of S-adenosylhomocysteine hydrolase.
    Madhavan GV, McGee DP, Rydzewski RM, Boehme R, Martin JC, Prisbe EJ.
    J Med Chem; 1988 Sep 01; 31(9):1798-804. PubMed ID: 2842505
    [Abstract] [Full Text] [Related]

  • 7. Potential inhibitors of S-adenosylmethionine-dependent methyltransferases. 11. Molecular dissections of neplanocin A as potential inhibitors of S-adenosylhomocysteine hydrolase.
    Borcherding DR, Narayanan S, Hasobe M, McKee JG, Keller BT, Borchardt RT.
    J Med Chem; 1988 Sep 01; 31(9):1729-38. PubMed ID: 3411600
    [Abstract] [Full Text] [Related]

  • 8. Antiviral potency of adenosine analogues: correlation with inhibition of S-adenosylhomocysteine hydrolase.
    De Clercq E, Cools M.
    Biochem Biophys Res Commun; 1985 May 31; 129(1):306-11. PubMed ID: 2988550
    [Abstract] [Full Text] [Related]

  • 9. Antiviral and antimetabolic activities of neplanocins.
    De Clercq E.
    Antimicrob Agents Chemother; 1985 Jul 31; 28(1):84-9. PubMed ID: 2994559
    [Abstract] [Full Text] [Related]

  • 10. Design, synthesis, and biological evaluation of fluoroneplanocin A as the novel mechanism-based inhibitor of S-adenosylhomocysteine hydrolase.
    Jeong LS, Yoo SJ, Lee KM, Koo MJ, Choi WJ, Kim HO, Moon HR, Lee MY, Park JG, Lee SK, Chun MW.
    J Med Chem; 2003 Jan 16; 46(2):201-3. PubMed ID: 12519056
    [Abstract] [Full Text] [Related]

  • 11. An epimer of 5'-noraristeromycin and its antiviral properties.
    Siddiqi SM, Chen X, Schneller SW, Ikeda S, Snoeck R, Andrei G, Balzarini J, De Clercq E.
    J Med Chem; 1994 Apr 29; 37(9):1382-4. PubMed ID: 8176716
    [Abstract] [Full Text] [Related]

  • 12. Influence of S-adenosylhomocysteine hydrolase inhibitors on S-adenosylhomocysteine and S-adenosylmethionine pool levels in L929 cells.
    Cools M, De Clercq E.
    Biochem Pharmacol; 1990 Nov 15; 40(10):2259-64. PubMed ID: 2244927
    [Abstract] [Full Text] [Related]

  • 13. Neplanocin A. A potent inhibitor of S-adenosylhomocysteine hydrolase and of vaccinia virus multiplication in mouse L929 cells.
    Borchardt RT, Keller BT, Patel-Thombre U.
    J Biol Chem; 1984 Apr 10; 259(7):4353-8. PubMed ID: 6707008
    [Abstract] [Full Text] [Related]

  • 14. Adenosine dialdehyde: a potent inhibitor of vaccinia virus multiplication in mouse L929 cells.
    Keller BT, Borchardt RT.
    Mol Pharmacol; 1987 May 10; 31(5):485-92. PubMed ID: 3574293
    [Abstract] [Full Text] [Related]

  • 15. New neplanocin analogues. 1. Synthesis of 6'-modified neplanocin A derivatives as broad-spectrum antiviral agents.
    Shuto S, Obara T, Toriya M, Hosoya M, Snoeck R, Andrei G, Balzarini J, De Clercq E.
    J Med Chem; 1992 Jan 24; 35(2):324-31. PubMed ID: 1732550
    [Abstract] [Full Text] [Related]

  • 16. John Montgomery's legacy: carbocyclic adenosine analogues as SAH hydrolase inhibitors with broad-spectrum antiviral activity.
    De Clercq E.
    Nucleosides Nucleotides Nucleic Acids; 2005 Jan 24; 24(10-12):1395-415. PubMed ID: 16438025
    [Abstract] [Full Text] [Related]

  • 17. Synthesis and biological activity of unsaturated carboacyclic purine nucleoside analogues.
    Haines DR, Tseng CK, Marquez VE.
    J Med Chem; 1987 May 24; 30(5):943-7. PubMed ID: 3033247
    [Abstract] [Full Text] [Related]

  • 18. Nucleic acid related compounds. 84. Synthesis of 6'-(E and Z)-halohomovinyl derivatives of adenosine, inactivation of S-adenosyl-L-homocysteine hydrolase, and correlation of anticancer and antiviral potencies with enzyme inhibition.
    Wnuk SF, Yuan CS, Borchardt RT, Balzarini J, De Clercq E, Robins MJ.
    J Med Chem; 1994 Oct 14; 37(21):3579-87. PubMed ID: 7932585
    [Abstract] [Full Text] [Related]

  • 19. Carbocyclic adenosine analogues as S-adenosylhomocysteine hydrolase inhibitors and antiviral agents: recent advances.
    De Clercq E.
    Nucleosides Nucleotides; 1998 Oct 14; 17(1-3):625-34. PubMed ID: 9708366
    [Abstract] [Full Text] [Related]

  • 20. 6'-Fluoro-3-deazaneplanocin: Synthesis and antiviral properties, including Ebola.
    Liu C, Chen Q, Cardinale S, Bowlin TL, Schneller SW.
    Bioorg Med Chem Lett; 2018 Dec 15; 28(23-24):3674-3675. PubMed ID: 30385162
    [Abstract] [Full Text] [Related]

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