These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

101 related items for PubMed ID: 25448278

  • 1. Pifithrin-alpha has a p53-independent cytoprotective effect on docosahexaenoic acid-induced cytotoxicity in human hepatocellular carcinoma HepG2 cells.
    Kanno S, Kurauchi K, Tomizawa A, Yomogida S, Ishikawa M.
    Toxicol Lett; 2015 Jan 22; 232(2):393-402. PubMed ID: 25448278
    [Abstract] [Full Text] [Related]

  • 2. Differential protection and transactivation of P53, P21, Bcl2, PCNA, cyclin G, and MDM2 genes in rat liver and the HepG2 cell line upon exposure to pifithrin.
    Farah IO, Begum RA, Ishaque AB.
    Biomed Sci Instrum; 2007 Jan 22; 43():116-21. PubMed ID: 17487067
    [Abstract] [Full Text] [Related]

  • 3. Albumin modulates docosahexaenoic acid-induced cytotoxicity in human hepatocellular carcinoma cell lines.
    Kanno S, Kurauchi K, Tomizawa A, Yomogida S, Ishikawa M.
    Toxicol Lett; 2011 Feb 05; 200(3):154-61. PubMed ID: 21108996
    [Abstract] [Full Text] [Related]

  • 4.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 5.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 6. P53 activation plays a crucial role in silibinin induced ROS generation via PUMA and JNK.
    Fan S, Qi M, Yu Y, Li L, Yao G, Tashiro S, Onodera S, Ikejima T.
    Free Radic Res; 2012 Mar 05; 46(3):310-9. PubMed ID: 22283740
    [Abstract] [Full Text] [Related]

  • 7. Pifithrin-alpha decreases the radioprotective efficacy of a Podophyllum hexandrum Himalayan mayapple fraction REC-2006 in HepG2 cells.
    Singh PK, Kumar R, Sharma A, Arora R, Jain SK, Sharma RK.
    Biotechnol Appl Biochem; 2009 Jul 09; 54(1):53-64. PubMed ID: 19409072
    [Abstract] [Full Text] [Related]

  • 8. The p53 inactivators pifithrin-μ and pifithrin-α mitigate TBI-induced neuronal damage through regulation of oxidative stress, neuroinflammation, autophagy and mitophagy.
    Yang LY, Greig NH, Tweedie D, Jung YJ, Chiang YH, Hoffer BJ, Miller JP, Chang KH, Wang JY.
    Exp Neurol; 2020 Feb 09; 324():113135. PubMed ID: 31778663
    [Abstract] [Full Text] [Related]

  • 9. Post-trauma administration of the pifithrin-α oxygen analog improves histological and functional outcomes after experimental traumatic brain injury.
    Yang LY, Chu YH, Tweedie D, Yu QS, Pick CG, Hoffer BJ, Greig NH, Wang JY.
    Exp Neurol; 2015 Jul 09; 269():56-66. PubMed ID: 25819102
    [Abstract] [Full Text] [Related]

  • 10. Pifithrin-α provides neuroprotective effects at the level of mitochondria independently of p53 inhibition.
    Neitemeier S, Ganjam GK, Diemert S, Culmsee C.
    Apoptosis; 2014 Dec 09; 19(12):1665-77. PubMed ID: 25343947
    [Abstract] [Full Text] [Related]

  • 11. Pifithrin-α as a potential cytoprotective agent in radiotherapy: protection of normal tissue without decreasing therapeutic efficacy in glioma cells.
    Sinn B, Schulze J, Schroeder G, Konschak R, Freyer D, Budach V, Tinhofer I.
    Radiat Res; 2010 Nov 09; 174(5):601-10. PubMed ID: 20718603
    [Abstract] [Full Text] [Related]

  • 12. Pivotal roles of p53 transcription-dependent and -independent pathways in manganese-induced mitochondrial dysfunction and neuronal apoptosis.
    Wan C, Ma X, Shi S, Zhao J, Nie X, Han J, Xiao J, Wang X, Jiang S, Jiang J.
    Toxicol Appl Pharmacol; 2014 Dec 15; 281(3):294-302. PubMed ID: 25448048
    [Abstract] [Full Text] [Related]

  • 13.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 14. Pifithrin-α alters p53 post-translational modifications pattern and differentially inhibits p53 target genes.
    Zhu J, Singh M, Selivanova G, Peuget S.
    Sci Rep; 2020 Jan 23; 10(1):1049. PubMed ID: 31974452
    [Abstract] [Full Text] [Related]

  • 15. An evaluation of the ability of pifithrin-alpha and -beta to inhibit p53 function in two wild-type p53 human tumor cell lines.
    Walton MI, Wilson SC, Hardcastle IR, Mirza AR, Workman P.
    Mol Cancer Ther; 2005 Sep 23; 4(9):1369-77. PubMed ID: 16170029
    [Abstract] [Full Text] [Related]

  • 16. Targeting the p53 pathway to protect the neonatal ischemic brain.
    Nijboer CH, Heijnen CJ, van der Kooij MA, Zijlstra J, van Velthoven CT, Culmsee C, van Bel F, Hagberg H, Kavelaars A.
    Ann Neurol; 2011 Aug 23; 70(2):255-64. PubMed ID: 21674585
    [Abstract] [Full Text] [Related]

  • 17. Pifithrin-alpha (PFT-alpha) caused differential protection of rat liver cells and HepG2 cell line in response to the selective cytotoxicity of arsenic and cadmium.
    Begum RA, Farah IO, Ishaque AB.
    Biomed Sci Instrum; 2002 Aug 23; 38():41-6. PubMed ID: 12085641
    [Abstract] [Full Text] [Related]

  • 18. The p53 inhibitor, pifithrin-α, disrupts microtubule organization, arrests growth, and induces polyploidy in the rainbow trout gill cell line, RTgill-W1.
    Zeng F, Yu X, Sherry JP, Dixon B, Duncker BP, Bols NC.
    Comp Biochem Physiol C Toxicol Pharmacol; 2016 Jan 23; 179():1-10. PubMed ID: 26291498
    [Abstract] [Full Text] [Related]

  • 19.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 20. Pifithrin-α, an inhibitor of p53 transactivation, up-regulates COX-2 expression through an MAPK-dependent pathway.
    Kim S, Han J, Lee SK, Hur SM, Koo M, Cho DH, Bae SY, Choi MY, Shin I, Yang JH, Nam SJ, Lee JE.
    Pharmacology; 2010 Jan 23; 86(5-6):313-9. PubMed ID: 21071999
    [Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 6.