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Journal Abstract Search


441 related items for PubMed ID: 25448441

  • 1. A comprehensive evaluation of the efficacy of leading oxime therapies in guinea pigs exposed to organophosphorus chemical warfare agents or pesticides.
    Wilhelm CM, Snider TH, Babin MC, Jett DA, Platoff GE, Yeung DT.
    Toxicol Appl Pharmacol; 2014 Dec 15; 281(3):254-65. PubMed ID: 25448441
    [Abstract] [Full Text] [Related]

  • 2. Evaluating the broad-spectrum efficacy of the acetylcholinesterase oximes reactivators MMB4 DMS, HLö-7 DMS, and 2-PAM Cl against phorate oxon, sarin, and VX in the Hartley guinea pig.
    Wilhelm CM, Snider TH, Babin MC, Platoff GE, Jett DA, Yeung DT.
    Neurotoxicology; 2018 Sep 15; 68():142-148. PubMed ID: 30056178
    [Abstract] [Full Text] [Related]

  • 3. Toxicity and median effective doses of oxime therapies against percutaneous organophosphorus pesticide and nerve agent challenges in the Hartley guinea pig.
    Snider TH, Babin MC, Jett DA, Platoff GE, Yeung DT.
    J Toxicol Sci; 2016 Sep 15; 41(4):511-21. PubMed ID: 27432237
    [Abstract] [Full Text] [Related]

  • 4. Efficacy of Recommended Prehospital Human Equivalent Doses of Atropine and Pralidoxime Against the Toxic Effects of Carbamate Poisoning in the Hartley Guinea Pig.
    Brittain MK, McGarry KG, Moyer RA, Babin MC, Jett DA, Platoff GE, Yeung DT.
    Int J Toxicol; 2016 May 15; 35(3):344-57. PubMed ID: 27102179
    [Abstract] [Full Text] [Related]

  • 5. An evaluation of therapeutic and reactivating effects of newly developed oximes (K156, K203) and commonly used oximes (obidoxime, trimedoxime, HI-6) in tabun-poisoned rats and mice.
    Kassa J, Karasova J, Musilek K, Kuca K.
    Toxicology; 2008 Jan 20; 243(3):311-6. PubMed ID: 18054821
    [Abstract] [Full Text] [Related]

  • 6. A comparison of the potency of a novel bispyridinium oxime K203 and currently available oximes (obidoxime, HI-6) to counteract the acute neurotoxicity of sarin in rats.
    Kassa J, Misik J, Karasova JZ.
    Basic Clin Pharmacol Toxicol; 2012 Nov 20; 111(5):333-8. PubMed ID: 22536919
    [Abstract] [Full Text] [Related]

  • 7. Efficacy and pharmacokinetic/pharmacodynamic study of 1,1'-methylenebis{4-[(hydroxyimino)methyl] pyridinium} dimethanesulfonate in guinea pigs and rhesus macaques exposed to cyclosarin.
    Harvilchuck JA, Hong SP, Richey JS, Osheroff MR, Johnson JD.
    Int J Toxicol; 2013 Nov 20; 32(4 Suppl):108S-17S. PubMed ID: 23929444
    [Abstract] [Full Text] [Related]

  • 8. Kinetic analysis of oxime-assisted reactivation of human, Guinea pig, and rat acetylcholinesterase inhibited by the organophosphorus pesticide metabolite phorate oxon (PHO).
    Moyer RA, McGarry KG, Babin MC, Platoff GE, Jett DA, Yeung DT.
    Pestic Biochem Physiol; 2018 Feb 20; 145():93-99. PubMed ID: 29482737
    [Abstract] [Full Text] [Related]

  • 9. Unequal efficacy of pyridinium oximes in acute organophosphate poisoning.
    Antonijevic B, Stojiljkovic MP.
    Clin Med Res; 2007 Mar 20; 5(1):71-82. PubMed ID: 17456837
    [Abstract] [Full Text] [Related]

  • 10. A comparison of the reactivating and therapeutic efficacy of two novel bispyridinium oximes (K727, K733) with the oxime HI-6 and obidoxime in sarin-poisoned rats and mice.
    Kassa J, Sepsova V, Matouskova L, Horova A, Musilek K.
    Toxicol Mech Methods; 2015 Mar 20; 25(3):229-33. PubMed ID: 25894563
    [Abstract] [Full Text] [Related]

  • 11. Dose-response effects of atropine and HI-6 treatment of organophosphorus poisoning in guinea pigs.
    Koplovitz I, Menton R, Matthews C, Shutz M, Nalls C, Kelly S.
    Drug Chem Toxicol; 1995 Mar 20; 18(2-3):119-36. PubMed ID: 7497907
    [Abstract] [Full Text] [Related]

  • 12. Pyridinium oximes: rationale for their selection as causal antidotes against organophosphate poisonings and current solutions for auto-injectors.
    Stojiljković MP, Jokanović M.
    Arh Hig Rada Toksikol; 2006 Dec 20; 57(4):435-43. PubMed ID: 17265683
    [Abstract] [Full Text] [Related]

  • 13. Assessing the therapeutic efficacy of oxime therapies against percutaneous organophosphorus pesticide and nerve agent challenges in the Hartley guinea pig.
    Snider TH, Wilhelm CM, Babin MC, Platoff GE, Yeung DT.
    J Toxicol Sci; 2015 Dec 20; 40(6):759-75. PubMed ID: 26558457
    [Abstract] [Full Text] [Related]

  • 14. An evaluation of reactivating and therapeutic efficacy of newly developed oximes (K206, K269) and commonly used oximes (obidoxime, HI-6) in cyclosarin-poisoned rats and mice.
    Kassa J, Karasova J, Musilek K, Kuca K, Bajgar J.
    Clin Toxicol (Phila); 2009 Jan 20; 47(1):72-6. PubMed ID: 18686075
    [Abstract] [Full Text] [Related]

  • 15. The efficacy of HI-6 DMS in a sustained infusion against percutaneous VX poisoning in the guinea-pig.
    Whitmore C, Cook AR, Mann T, Price ME, Emery E, Roughley N, Flint D, Stubbs S, Armstrong SJ, Rice H, Tattersall JEH.
    Toxicol Lett; 2018 Sep 01; 293():207-215. PubMed ID: 29129798
    [Abstract] [Full Text] [Related]

  • 16. A comparison of the efficacy of HI6 and 2-PAM against soman, tabun, sarin, and VX in the rabbit.
    Koplovitz I, Stewart JR.
    Toxicol Lett; 1994 Feb 15; 70(3):269-79. PubMed ID: 8284794
    [Abstract] [Full Text] [Related]

  • 17. Suitability of human butyrylcholinesterase as therapeutic marker and pseudo catalytic scavenger in organophosphate poisoning: a kinetic analysis.
    Aurbek N, Thiermann H, Eyer F, Eyer P, Worek F.
    Toxicology; 2009 May 17; 259(3):133-9. PubMed ID: 19428953
    [Abstract] [Full Text] [Related]

  • 18. Efficacy of the oxime HI-6 dimethanesulphonate in the treatment of guinea-pigs exposed to the nerve agents GB and GD.
    Rice H, Whitfield SJ, Fairhall SJ, Scott IR, Steventon GB, Tattersall JEH.
    Toxicol Lett; 2024 Jan 17; 391():26-31. PubMed ID: 38048886
    [Abstract] [Full Text] [Related]

  • 19. Oximes in organophosphate poisoning: 60 years of hope and despair.
    Worek F, Thiermann H, Wille T.
    Chem Biol Interact; 2016 Nov 25; 259(Pt B):93-98. PubMed ID: 27125761
    [Abstract] [Full Text] [Related]

  • 20. Efficacy of the antinicotinic compound MB327 against soman poisoning - Importance of experimental end point.
    Price ME, Whitmore CL, Tattersall JEH, Green AC, Rice H.
    Toxicol Lett; 2018 Sep 01; 293():167-171. PubMed ID: 29127032
    [Abstract] [Full Text] [Related]


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