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Journal Abstract Search

202 related items for PubMed ID: 25449979

  • 1. Stage specific activity of synthetic antimalarial endoperoxides, N-89 and N-251, against Plasmodium falciparum.
    Morita M, Koyama T, Sanai H, Sato A, Hiramoto A, Masuyama A, Nojima M, Wataya Y, Kim HS.
    Parasitol Int; 2015 Feb; 64(1):113-7. PubMed ID: 25449979
    [Abstract] [Full Text] [Related]

  • 2. Plasmodium falciparum endoplasmic reticulum-resident calcium binding protein is a possible target of synthetic antimalarial endoperoxides, N-89 and N-251.
    Morita M, Sanai H, Hiramoto A, Sato A, Hiraoka O, Sakura T, Kaneko O, Masuyama A, Nojima M, Wataya Y, Kim HS.
    J Proteome Res; 2012 Dec 07; 11(12):5704-11. PubMed ID: 23061985
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  • 3. Antimalarial activity of endoperoxide compound 6-(1,2,6,7-tetraoxaspiro[7.11]nonadec-4-yl)hexan-1-ol.
    Sato A, Hiramoto A, Morita M, Matsumoto M, Komich Y, Nakase Y, Tanigawa N, Hiraoka O, Hiramoto K, Hayatsu H, Higaki K, Kawai S, Masuyama A, Nojima M, Wataya Y, Kim HS.
    Parasitol Int; 2011 Sep 07; 60(3):270-3. PubMed ID: 21501696
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  • 4. Comparative ex vivo activity of novel endoperoxides in multidrug-resistant plasmodium falciparum and P. vivax.
    Marfurt J, Chalfein F, Prayoga P, Wabiser F, Wirjanata G, Sebayang B, Piera KA, Wittlin S, Haynes RK, Möhrle JJ, Anstey NM, Kenangalem E, Price RN.
    Antimicrob Agents Chemother; 2012 Oct 07; 56(10):5258-63. PubMed ID: 22850522
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  • 5. Comparison of the reactivity of antimalarial 1,2,4,5-tetraoxanes with 1,2,4-trioxolanes in the presence of ferrous iron salts, heme, and ferrous iron salts/phosphatidylcholine.
    Bousejra-El Garah F, Wong MH, Amewu RK, Muangnoicharoen S, Maggs JL, Stigliani JL, Park BK, Chadwick J, Ward SA, O'Neill PM.
    J Med Chem; 2011 Oct 13; 54(19):6443-55. PubMed ID: 21888440
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  • 6. Considerations on the mechanism of action of artemisinin antimalarials: part 1--the 'carbon radical' and 'heme' hypotheses.
    Haynes RK, Cheu KW, N'Da D, Coghi P, Monti D.
    Infect Disord Drug Targets; 2013 Aug 13; 13(4):217-77. PubMed ID: 24304352
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  • 8. Assessment of the antimalarial potential of tetraoxane WR 148999.
    Vennerstrom JL, Ager AL, Andersen SL, Grace JM, Wongpanich V, Angerhofer CK, Hu JK, Wesche DL.
    Am J Trop Med Hyg; 2000 May 13; 62(5):573-8. PubMed ID: 11289666
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  • 9. Exploration of artemisinin derivatives and synthetic peroxides in antimalarial drug discovery research.
    Patel OPS, Beteck RM, Legoabe LJ.
    Eur J Med Chem; 2021 Mar 05; 213():113193. PubMed ID: 33508479
    [Abstract] [Full Text] [Related]

  • 10. Enantiomeric 1,2,4-trioxanes display equivalent in vitro antimalarial activity versus Plasmodium falciparum malaria parasites: implications for the molecular mechanism of action of the artemisinins.
    O'Neill PM, Rawe SL, Borstnik K, Miller A, Ward SA, Bray PG, Davies J, Oh CH, Posner GH.
    Chembiochem; 2005 Nov 05; 6(11):2048-54. PubMed ID: 16222725
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  • 11. Potential of synthetic endoperoxides against Trichomonas vaginalis in vitro.
    Seo MY, Ryu JS, Sato A, Kurosaki Y, Chang KS, Kim HS.
    Parasitol Int; 2017 Oct 05; 66(5):619-621. PubMed ID: 28571765
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  • 13. Probing the antimalarial mechanism of artemisinin and OZ277 (arterolane) with nonperoxidic isosteres and nitroxyl radicals.
    Fügi MA, Wittlin S, Dong Y, Vennerstrom JL.
    Antimicrob Agents Chemother; 2010 Mar 05; 54(3):1042-6. PubMed ID: 20028825
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  • 14. Two-step synthesis of achiral dispiro-1,2,4,5-tetraoxanes with outstanding antimalarial activity, low toxicity, and high-stability profiles.
    Ellis GL, Amewu R, Sabbani S, Stocks PA, Shone A, Stanford D, Gibbons P, Davies J, Vivas L, Charnaud S, Bongard E, Hall C, Rimmer K, Lozanom S, Jesús M, Gargallo D, Ward SA, O'Neill PM.
    J Med Chem; 2008 Apr 10; 51(7):2170-7. PubMed ID: 18341274
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  • 15. Optimal assay design for determining the in vitro sensitivity of ring stage Plasmodium falciparum to artemisinins.
    Xie SC, Dogovski C, Kenny S, Tilley L, Klonis N.
    Int J Parasitol; 2014 Oct 15; 44(12):893-9. PubMed ID: 25161101
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  • 16. 1,2,4,5-Tetraoxane derivatives/hybrids as potent antimalarial endoperoxides: Chronological advancements, structure-activity relationship (SAR) studies and future perspectives.
    T A AR, Rajendra TN, Suhas KP, Ippagunta SK, Chaudhary S.
    Med Res Rev; 2024 Sep 15; 44(5):2266-2290. PubMed ID: 38618882
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  • 19. In vitro and in vivo interaction of synthetic peroxide RBx11160 (OZ277) with piperaquine in Plasmodium models.
    Snyder C, Chollet J, Santo-Tomas J, Scheurer C, Wittlin S.
    Exp Parasitol; 2007 Mar 15; 115(3):296-300. PubMed ID: 17087929
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  • 20. A tetraoxane-based antimalarial drug candidate that overcomes PfK13-C580Y dependent artemisinin resistance.
    O'Neill PM, Amewu RK, Charman SA, Sabbani S, Gnädig NF, Straimer J, Fidock DA, Shore ER, Roberts NL, Wong MH, Hong WD, Pidathala C, Riley C, Murphy B, Aljayyoussi G, Gamo FJ, Sanz L, Rodrigues J, Cortes CG, Herreros E, Angulo-Barturén I, Jiménez-Díaz MB, Bazaga SF, Martínez-Martínez MS, Campo B, Sharma R, Ryan E, Shackleford DM, Campbell S, Smith DA, Wirjanata G, Noviyanti R, Price RN, Marfurt J, Palmer MJ, Copple IM, Mercer AE, Ruecker A, Delves MJ, Sinden RE, Siegl P, Davies J, Rochford R, Kocken CHM, Zeeman AM, Nixon GL, Biagini GA, Ward SA.
    Nat Commun; 2017 May 24; 8():15159. PubMed ID: 28537265
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