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298 related items for PubMed ID: 25450672

  • 1. Antagonism of human formyl peptide receptor 1 (FPR1) by chromones and related isoflavones.
    Schepetkin IA, Kirpotina LN, Khlebnikov AI, Cheng N, Ye RD, Quinn MT.
    Biochem Pharmacol; 2014 Dec 15; 92(4):627-41. PubMed ID: 25450672
    [Abstract] [Full Text] [Related]

  • 2. 4-Aroyl-3-hydroxy-5-phenyl-1H-pyrrol-2(5H)-ones as N-formyl peptide receptor 1 (FPR1) antagonists.
    Kirpotina LN, Schepetkin IA, Khlebnikov AI, Ruban OI, Ge Y, Ye RD, Kominsky DJ, Quinn MT.
    Biochem Pharmacol; 2017 Oct 15; 142():120-132. PubMed ID: 28690139
    [Abstract] [Full Text] [Related]

  • 3. Gastrin-releasing peptide/neuromedin B receptor antagonists PD176252, PD168368, and related analogs are potent agonists of human formyl-peptide receptors.
    Schepetkin IA, Kirpotina LN, Khlebnikov AI, Jutila MA, Quinn MT.
    Mol Pharmacol; 2011 Jan 15; 79(1):77-90. PubMed ID: 20943772
    [Abstract] [Full Text] [Related]

  • 4. A non-peptide receptor inhibitor with selectivity for one of the neutrophil formyl peptide receptors, FPR 1.
    Cevik-Aras H, Kalderén C, Jenmalm Jensen A, Oprea T, Dahlgren C, Forsman H.
    Biochem Pharmacol; 2012 Jun 15; 83(12):1655-62. PubMed ID: 22410002
    [Abstract] [Full Text] [Related]

  • 5. Antagonism of human formyl peptide receptor 1 with natural compounds and their synthetic derivatives.
    Schepetkin IA, Khlebnikov AI, Kirpotina LN, Quinn MT.
    Int Immunopharmacol; 2016 Aug 15; 37():43-58. PubMed ID: 26382576
    [Abstract] [Full Text] [Related]

  • 6. Further studies on 2-arylacetamide pyridazin-3(2H)-ones: design, synthesis and evaluation of 4,6-disubstituted analogs as formyl peptide receptors (FPRs) agonists.
    Giovannoni MP, Schepetkin IA, Cilibrizzi A, Crocetti L, Khlebnikov AI, Dahlgren C, Graziano A, Dal Piaz V, Kirpotina LN, Zerbinati S, Vergelli C, Quinn MT.
    Eur J Med Chem; 2013 Jun 15; 64():512-28. PubMed ID: 23685570
    [Abstract] [Full Text] [Related]

  • 7. Identification of novel small-molecule agonists for human formyl peptide receptors and pharmacophore models of their recognition.
    Kirpotina LN, Khlebnikov AI, Schepetkin IA, Ye RD, Rabiet MJ, Jutila MA, Quinn MT.
    Mol Pharmacol; 2010 Feb 15; 77(2):159-70. PubMed ID: 19903830
    [Abstract] [Full Text] [Related]

  • 8. Functional selective FPR1 signaling in favor of an activation of the neutrophil superoxide generating NOX2 complex.
    Lind S, Dahlgren C, Holmdahl R, Olofsson P, Forsman H.
    J Leukoc Biol; 2021 Jun 15; 109(6):1105-1120. PubMed ID: 33040403
    [Abstract] [Full Text] [Related]

  • 9. The formyl peptide fMLF primes platelet activation and augments thrombus formation.
    Salamah MF, Ravishankar D, Vaiyapuri R, Moraes LA, Patel K, Perretti M, Gibbins JM, Vaiyapuri S.
    J Thromb Haemost; 2019 Jul 15; 17(7):1120-1133. PubMed ID: 31033193
    [Abstract] [Full Text] [Related]

  • 10. The immunosuppressant cyclosporin A antagonizes human formyl peptide receptor through inhibition of cognate ligand binding.
    Yan P, Nanamori M, Sun M, Zhou C, Cheng N, Li N, Zheng W, Xiao L, Xie X, Ye RD, Wang MW.
    J Immunol; 2006 Nov 15; 177(10):7050-8. PubMed ID: 17082621
    [Abstract] [Full Text] [Related]

  • 11. Honokiol suppresses formyl peptide-induced human neutrophil activation by blocking formyl peptide receptor 1.
    Liu FC, Yu HP, Syu YT, Fang JY, Lin CF, Chang SH, Lee YT, Hwang TL.
    Sci Rep; 2017 Jul 27; 7(1):6718. PubMed ID: 28751674
    [Abstract] [Full Text] [Related]

  • 12. Garcinia Multiflora Inhibits FPR1-Mediated Neutrophil Activation and Protects Against Acute Lung Injury.
    Tsai YF, Yang SC, Chang WY, Chen JJ, Chen CY, Chang SH, Hwang TL.
    Cell Physiol Biochem; 2018 Jul 27; 51(6):2776-2793. PubMed ID: 30562761
    [Abstract] [Full Text] [Related]

  • 13. The leukocyte chemotactic receptor FPR2, but not the closely related FPR1, is sensitive to cell-penetrating pepducins with amino acid sequences descending from the third intracellular receptor loop.
    Forsman H, Bylund J, Oprea TI, Karlsson A, Boulay F, Rabiet MJ, Dahlgren C.
    Biochim Biophys Acta; 2013 Aug 27; 1833(8):1914-23. PubMed ID: 23562731
    [Abstract] [Full Text] [Related]

  • 14. 3-(1H-indol-3-yl)-2-[3-(4-nitrophenyl)ureido]propanamide enantiomers with human formyl-peptide receptor agonist activity: molecular modeling of chiral recognition by FPR2.
    Schepetkin IA, Kirpotina LN, Khlebnikov AI, Leopoldo M, Lucente E, Lacivita E, De Giorgio P, Quinn MT.
    Biochem Pharmacol; 2013 Feb 01; 85(3):404-16. PubMed ID: 23219934
    [Abstract] [Full Text] [Related]

  • 15. Identification of C-terminal phosphorylation sites of N-formyl peptide receptor-1 (FPR1) in human blood neutrophils.
    Maaty WS, Lord CI, Gripentrog JM, Riesselman M, Keren-Aviram G, Liu T, Dratz EA, Bothner B, Jesaitis AJ.
    J Biol Chem; 2013 Sep 20; 288(38):27042-27058. PubMed ID: 23873933
    [Abstract] [Full Text] [Related]

  • 16. Applying label-free dynamic mass redistribution assay for studying endogenous FPR1 receptor signalling in human neutrophils.
    Christensen HB, Gloriam DE, Pedersen DS, Cowland JB, Borregaard N, Bräuner-Osborne H.
    J Pharmacol Toxicol Methods; 2017 Nov 20; 88(Pt 1):72-78. PubMed ID: 28716665
    [Abstract] [Full Text] [Related]

  • 17. Synthesis of Five- and Six-Membered N-Phenylacetamido Substituted Heterocycles as Formyl Peptide Receptor Agonists.
    Vergelli C, Schepetkin IA, Ciciani G, Cilibrizzi A, Crocetti L, Giovannoni MP, Guerrini G, Iacovone A, Kirpotina LN, Ye RD, Quinn MT.
    Drug Dev Res; 2017 Feb 20; 78(1):49-62. PubMed ID: 27859446
    [Abstract] [Full Text] [Related]

  • 18. Novel formyl peptide receptor (FPR) agonists with pyridinone and pyrimidindione scaffolds that are potentially useful for the treatment of rheumatoid arthritis.
    Crocetti L, Vergelli C, Guerrini G, Cantini N, Kirpotina LN, Schepetkin IA, Quinn MT, Parisio C, Di Cesare Mannelli L, Ghelardini C, Giovannoni MP.
    Bioorg Chem; 2020 Jul 20; 100():103880. PubMed ID: 32388428
    [Abstract] [Full Text] [Related]

  • 19. Peptide length and folding state govern the capacity of staphylococcal β-type phenol-soluble modulins to activate human formyl-peptide receptors 1 or 2.
    Kretschmer D, Rautenberg M, Linke D, Peschel A.
    J Leukoc Biol; 2015 Apr 20; 97(4):689-97. PubMed ID: 25724390
    [Abstract] [Full Text] [Related]

  • 20. Dipeptide HCH6-1 inhibits neutrophil activation and protects against acute lung injury by blocking FPR1.
    Yang SC, Chang SH, Hsieh PW, Huang YT, Ho CM, Tsai YF, Hwang TL.
    Free Radic Biol Med; 2017 May 20; 106():254-269. PubMed ID: 28232203
    [Abstract] [Full Text] [Related]

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