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Journal Abstract Search

1282 related items for PubMed ID: 25458114

  • 1. Emerging structural insights into biased GPCR signaling.
    Shukla AK, Singh G, Ghosh E.
    Trends Biochem Sci; 2014 Dec; 39(12):594-602. PubMed ID: 25458114
    [Abstract] [Full Text] [Related]

  • 2. Elucidating structural and molecular mechanisms of β-arrestin-biased agonism at GPCRs via MS-based proteomics.
    Xiao K, Sun J.
    Cell Signal; 2018 Jan; 41():56-64. PubMed ID: 28939107
    [Abstract] [Full Text] [Related]

  • 3. Biasing GPCR signaling from inside.
    Shukla AK.
    Sci Signal; 2014 Jan 28; 7(310):pe3. PubMed ID: 24473194
    [Abstract] [Full Text] [Related]

  • 4. Understanding the GPCR biased signaling through G protein and arrestin complex structures.
    Zhou XE, Melcher K, Xu HE.
    Curr Opin Struct Biol; 2017 Aug 28; 45():150-159. PubMed ID: 28558341
    [Abstract] [Full Text] [Related]

  • 5. Pilot the pulse: controlling the multiplicity of receptor dynamics.
    Bock A, Kostenis E, Tränkle C, Lohse MJ, Mohr K.
    Trends Pharmacol Sci; 2014 Dec 28; 35(12):630-8. PubMed ID: 25455830
    [Abstract] [Full Text] [Related]

  • 6. Structural biology of G protein-coupled receptor signaling complexes.
    Edward Zhou X, Melcher K, Eric Xu H.
    Protein Sci; 2019 Mar 28; 28(3):487-501. PubMed ID: 30311978
    [Abstract] [Full Text] [Related]

  • 7. Conformational Basis of G Protein-Coupled Receptor Signaling Versatility.
    Wingler LM, Lefkowitz RJ.
    Trends Cell Biol; 2020 Sep 28; 30(9):736-747. PubMed ID: 32622699
    [Abstract] [Full Text] [Related]

  • 8. Fulfilling the Promise of "Biased" G Protein-Coupled Receptor Agonism.
    Luttrell LM, Maudsley S, Bohn LM.
    Mol Pharmacol; 2015 Sep 28; 88(3):579-88. PubMed ID: 26134495
    [Abstract] [Full Text] [Related]

  • 9. How Ligands Illuminate GPCR Molecular Pharmacology.
    Wacker D, Stevens RC, Roth BL.
    Cell; 2017 Jul 27; 170(3):414-427. PubMed ID: 28753422
    [Abstract] [Full Text] [Related]

  • 10. Conformational complexity of G-protein-coupled receptors.
    Kobilka BK, Deupi X.
    Trends Pharmacol Sci; 2007 Aug 27; 28(8):397-406. PubMed ID: 17629961
    [Abstract] [Full Text] [Related]

  • 11. [G-protein-coupled receptors plasticity and signalling].
    Galés C.
    Med Sci (Paris); 2012 Oct 27; 28(10):883-5. PubMed ID: 23067421
    [Abstract] [Full Text] [Related]

  • 12. Biased ligands for better cardiovascular drugs: dissecting G-protein-coupled receptor pharmacology.
    DeWire SM, Violin JD.
    Circ Res; 2011 Jul 08; 109(2):205-16. PubMed ID: 21737816
    [Abstract] [Full Text] [Related]

  • 13. Biased signaling of G protein coupled receptors (GPCRs): Molecular determinants of GPCR/transducer selectivity and therapeutic potential.
    Seyedabadi M, Ghahremani MH, Albert PR.
    Pharmacol Ther; 2019 Aug 08; 200():148-178. PubMed ID: 31075355
    [Abstract] [Full Text] [Related]

  • 14. Unravelling intrinsic efficacy and ligand bias at G protein coupled receptors: A practical guide to assessing functional data.
    Stott LA, Hall DA, Holliday ND.
    Biochem Pharmacol; 2016 Feb 01; 101():1-12. PubMed ID: 26478533
    [Abstract] [Full Text] [Related]

  • 15. Biased agonism at G protein-coupled receptors: the promise and the challenges--a medicinal chemistry perspective.
    Shonberg J, Lopez L, Scammells PJ, Christopoulos A, Capuano B, Lane JR.
    Med Res Rev; 2014 Nov 01; 34(6):1286-330. PubMed ID: 24796277
    [Abstract] [Full Text] [Related]

  • 16. G Protein-coupled Receptor Biased Agonism.
    Hodavance SY, Gareri C, Torok RD, Rockman HA.
    J Cardiovasc Pharmacol; 2016 Mar 01; 67(3):193-202. PubMed ID: 26751266
    [Abstract] [Full Text] [Related]

  • 17. Ligand- and heterodimer-directed signaling of the CB(1) cannabinoid receptor.
    Hudson BD, Hébert TE, Kelly ME.
    Mol Pharmacol; 2010 Jan 01; 77(1):1-9. PubMed ID: 19837905
    [Abstract] [Full Text] [Related]

  • 18. Allosteric coupling and biased agonism in G protein-coupled receptors.
    Bock A, Bermudez M.
    FEBS J; 2021 Apr 01; 288(8):2513-2528. PubMed ID: 33621418
    [Abstract] [Full Text] [Related]

  • 19. Towards tissue-specific pharmacology: insights from the calcium-sensing receptor as a paradigm for GPCR (patho)physiological bias.
    Leach K, Conigrave AD, Sexton PM, Christopoulos A.
    Trends Pharmacol Sci; 2015 Apr 01; 36(4):215-25. PubMed ID: 25765207
    [Abstract] [Full Text] [Related]

  • 20. Modeling G protein-coupled receptors in complex with biased agonists.
    Costanzi S.
    Trends Pharmacol Sci; 2014 Jun 01; 35(6):277-83. PubMed ID: 24793542
    [Abstract] [Full Text] [Related]

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