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Journal Abstract Search


326 related items for PubMed ID: 25463043

  • 1. Calcium binding to gatekeeper residues flanking aggregation-prone segments underlies non-fibrillar amyloid traits in superoxide dismutase 1 (SOD1).
    Estácio SG, Leal SS, Cristóvão JS, Faísca PF, Gomes CM.
    Biochim Biophys Acta; 2015 Feb; 1854(2):118-26. PubMed ID: 25463043
    [Abstract] [Full Text] [Related]

  • 2. Calcium ions promote superoxide dismutase 1 (SOD1) aggregation into non-fibrillar amyloid: a link to toxic effects of calcium overload in amyotrophic lateral sclerosis (ALS)?
    Leal SS, Cardoso I, Valentine JS, Gomes CM.
    J Biol Chem; 2013 Aug 30; 288(35):25219-25228. PubMed ID: 23861388
    [Abstract] [Full Text] [Related]

  • 3. Amyotrophic lateral sclerosis is a non-amyloid disease in which extensive misfolding of SOD1 is unique to the familial form.
    Kerman A, Liu HN, Croul S, Bilbao J, Rogaeva E, Zinman L, Robertson J, Chakrabartty A.
    Acta Neuropathol; 2010 Mar 30; 119(3):335-44. PubMed ID: 20111867
    [Abstract] [Full Text] [Related]

  • 4. Molecular dynamics using atomic-resolution structure reveal structural fluctuations that may lead to polymerization of human Cu-Zn superoxide dismutase.
    Strange RW, Yong CW, Smith W, Hasnain SS.
    Proc Natl Acad Sci U S A; 2007 Jun 12; 104(24):10040-4. PubMed ID: 17548825
    [Abstract] [Full Text] [Related]

  • 5. Calcium dysregulation, mitochondrial pathology and protein aggregation in a culture model of amyotrophic lateral sclerosis: mechanistic relationship and differential sensitivity to intervention.
    Tradewell ML, Cooper LA, Minotti S, Durham HD.
    Neurobiol Dis; 2011 Jun 12; 42(3):265-75. PubMed ID: 21296666
    [Abstract] [Full Text] [Related]

  • 6. Superoxide Dismutase 1 (SOD1)-Derived Peptide Inhibits Amyloid Aggregation of Familial Amyotrophic Lateral Sclerosis SOD1 Mutants.
    Banerjee V, Shani T, Katzman B, Vyazmensky M, Papo N, Israelson A, Engel S.
    ACS Chem Neurosci; 2016 Nov 16; 7(11):1595-1606. PubMed ID: 27540759
    [Abstract] [Full Text] [Related]

  • 7. Curcumin binds to the pre-fibrillar aggregates of Cu/Zn superoxide dismutase (SOD1) and alters its amyloidogenic pathway resulting in reduced cytotoxicity.
    Bhatia NK, Srivastava A, Katyal N, Jain N, Khan MA, Kundu B, Deep S.
    Biochim Biophys Acta; 2015 May 16; 1854(5):426-36. PubMed ID: 25666897
    [Abstract] [Full Text] [Related]

  • 8. Aggregation-triggering segments of SOD1 fibril formation support a common pathway for familial and sporadic ALS.
    Ivanova MI, Sievers SA, Guenther EL, Johnson LM, Winkler DD, Galaleldeen A, Sawaya MR, Hart PJ, Eisenberg DS.
    Proc Natl Acad Sci U S A; 2014 Jan 07; 111(1):197-201. PubMed ID: 24344300
    [Abstract] [Full Text] [Related]

  • 9. A copper-deficient form of mutant Cu/Zn-superoxide dismutase as an early pathological species in amyotrophic lateral sclerosis.
    Tokuda E, Nomura T, Ohara S, Watanabe S, Yamanaka K, Morisaki Y, Misawa H, Furukawa Y.
    Biochim Biophys Acta Mol Basis Dis; 2018 Jun 07; 1864(6 Pt A):2119-2130. PubMed ID: 29551730
    [Abstract] [Full Text] [Related]

  • 10. Changes in hydrophobicity mainly promotes the aggregation tendency of ALS associated SOD1 mutants.
    Tompa DR, Kadhirvel S.
    Int J Biol Macromol; 2020 Feb 15; 145():904-913. PubMed ID: 31669277
    [Abstract] [Full Text] [Related]

  • 11. Cholesterol secosterol aldehyde adduction and aggregation of Cu,Zn-superoxide dismutase: Potential implications in ALS.
    Dantas LS, Chaves-Filho AB, Coelho FR, Genaro-Mattos TC, Tallman KA, Porter NA, Augusto O, Miyamoto S.
    Redox Biol; 2018 Oct 15; 19():105-115. PubMed ID: 30142602
    [Abstract] [Full Text] [Related]

  • 12. Local destabilization of the metal-binding region in human copper-zinc superoxide dismutase by remote mutations is a possible determinant for progression of ALS.
    Hennig J, Andrésen C, Museth AK, Lundström P, Tibell LA, Jonsson BH.
    Biochemistry; 2015 Jan 20; 54(2):323-33. PubMed ID: 25496420
    [Abstract] [Full Text] [Related]

  • 13. Mechanical probes of SOD1 predict systematic trends in metal and dimer affinity of ALS-associated mutants.
    Das A, Plotkin SS.
    J Mol Biol; 2013 Mar 11; 425(5):850-74. PubMed ID: 23291526
    [Abstract] [Full Text] [Related]

  • 14. Histological evidence of protein aggregation in mutant SOD1 transgenic mice and in amyotrophic lateral sclerosis neural tissues.
    Watanabe M, Dykes-Hoberg M, Culotta VC, Price DL, Wong PC, Rothstein JD.
    Neurobiol Dis; 2001 Dec 11; 8(6):933-41. PubMed ID: 11741389
    [Abstract] [Full Text] [Related]

  • 15. Loss of charge mutations in solvent exposed Lys residues of superoxide dismutase 1 do not induce inclusion formation in cultured cell models.
    Crosby K, Crown AM, Roberts BL, Brown H, Ayers JI, Borchelt DR.
    PLoS One; 2018 Dec 11; 13(11):e0206751. PubMed ID: 30399166
    [Abstract] [Full Text] [Related]

  • 16. A cysteine residue affects the conformational state and neuronal toxicity of mutant SOD1 in mice: relevance to the pathogenesis of ALS.
    Nagano S, Takahashi Y, Yamamoto K, Masutani H, Fujiwara N, Urushitani M, Araki T.
    Hum Mol Genet; 2015 Jun 15; 24(12):3427-39. PubMed ID: 25762155
    [Abstract] [Full Text] [Related]

  • 17. Structural instability and Cu-dependent pro-oxidant activity acquired by the apo form of mutant SOD1 associated with amyotrophic lateral sclerosis.
    Kitamura F, Fujimaki N, Okita W, Hiramatsu H, Takeuchi H.
    Biochemistry; 2011 May 24; 50(20):4242-50. PubMed ID: 21506602
    [Abstract] [Full Text] [Related]

  • 18. Solvent sensitivity of protein aggregation in Cu, Zn superoxide dismutase: a molecular dynamics simulation study.
    Prakash A, Kumar V, Pandey P, Bharti DR, Vishwakarma P, Singh R, Hassan MI, Lynn AM.
    J Biomol Struct Dyn; 2018 Aug 24; 36(10):2605-2617. PubMed ID: 28782426
    [Abstract] [Full Text] [Related]

  • 19. Glycerolipid Headgroups Control Rate and Mechanism of Superoxide Dismutase-1 Aggregation and Accelerate Fibrillization of Slowly Aggregating Amyotrophic Lateral Sclerosis Mutants.
    Rasouli S, Abdolvahabi A, Croom CM, Plewman DL, Shi Y, Shaw BF.
    ACS Chem Neurosci; 2018 Jul 18; 9(7):1743-1756. PubMed ID: 29649360
    [Abstract] [Full Text] [Related]

  • 20. [SOD1 gene mutations in patients with amyotrophic lateral sclerosis: potential for the method of molecular].
    Lysogorskaia EV, Rossokhin AV, Abramycheva NIu, Zakharova MN, Illarioshkin SN.
    Mol Biol (Mosk); 2013 Jul 18; 47(5):861-7. PubMed ID: 25509359
    [Abstract] [Full Text] [Related]


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