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Journal Abstract Search

154 related items for PubMed ID: 25466200

  • 1. Antimitotic activity of structurally simplified biaryl analogs of the anticancer agents colchicine and combretastatin A4.
    McNulty J, van den Berg S, Ma D, Tarade D, Joshi S, Church J.
    Bioorg Med Chem Lett; 2015 Jan 01; 25(1):117-21. PubMed ID: 25466200
    [Abstract] [Full Text] [Related]

  • 2. Synthesis and biological evaluation of novel heterocyclic derivatives of combretastatin A-4.
    Nguyen TT, Lomberget T, Tran NC, Colomb E, Nachtergaele L, Thoret S, Dubois J, Guillaume J, Abdayem R, Haftek M, Barret R.
    Bioorg Med Chem Lett; 2012 Dec 01; 22(23):7227-31. PubMed ID: 23063401
    [Abstract] [Full Text] [Related]

  • 3. Interactions of tubulin with potent natural and synthetic analogs of the antimitotic agent combretastatin: a structure-activity study.
    Lin CM, Singh SB, Chu PS, Dempcy RO, Schmidt JM, Pettit GR, Hamel E.
    Mol Pharmacol; 1988 Aug 01; 34(2):200-8. PubMed ID: 3412321
    [Abstract] [Full Text] [Related]

  • 4. Structural and biochemical comparison of the anti-mitotic agents colchicine, combretastatin A4 and amphethinile.
    McGown AT, Fox BW.
    Anticancer Drug Des; 1989 Mar 01; 3(4):249-54. PubMed ID: 2930627
    [Abstract] [Full Text] [Related]

  • 5. 3-(3,4,5-Trimethoxyphenylselenyl)-1H-indoles and their selenoxides as combretastatin A-4 analogs: microwave-assisted synthesis and biological evaluation.
    Wen Z, Xu J, Wang Z, Qi H, Xu Q, Bai Z, Zhang Q, Bao K, Wu Y, Zhang W.
    Eur J Med Chem; 2015 Jan 27; 90():184-94. PubMed ID: 25461319
    [Abstract] [Full Text] [Related]

  • 6. Structure-based discovery of a boronic acid bioisostere of combretastatin A-4.
    Kong Y, Grembecka J, Edler MC, Hamel E, Mooberry SL, Sabat M, Rieger J, Brown ML.
    Chem Biol; 2005 Sep 27; 12(9):1007-14. PubMed ID: 16183025
    [Abstract] [Full Text] [Related]

  • 7. Combretastatin A-4 analogues as antimitotic antitumor agents.
    Nam NH.
    Curr Med Chem; 2003 Sep 27; 10(17):1697-722. PubMed ID: 12871118
    [Abstract] [Full Text] [Related]

  • 8. 2-amino and 2'-aminocombretastatin derivatives as potent antimitotic agents.
    Chang JY, Yang MF, Chang CY, Chen CM, Kuo CC, Liou JP.
    J Med Chem; 2006 Oct 19; 49(21):6412-5. PubMed ID: 17034147
    [Abstract] [Full Text] [Related]

  • 9. Synthesis and biological evaluation of vinylogous combretastatin A-4 derivatives.
    Kaffy J, Pontikis R, Florent JC, Monneret C.
    Org Biomol Chem; 2005 Jul 21; 3(14):2657-60. PubMed ID: 15999202
    [Abstract] [Full Text] [Related]

  • 10. Antitumor agents. 141. Synthesis and biological evaluation of novel thiocolchicine analogs: N-acyl-, N-aroyl-, and N-(substituted benzyl)deacetylthiocolchicines as potent cytotoxic and antimitotic compounds.
    Sun L, Hamel E, Lin CM, Hastie SB, Pyluck A, Lee KH.
    J Med Chem; 1993 May 14; 36(10):1474-9. PubMed ID: 8496915
    [Abstract] [Full Text] [Related]

  • 11. Synthesis and biological evaluation of thiophene and benzo[b]thiophene analogs of combretastatin A-4 and isocombretastatin A-4: A comparison between the linkage positions of the 3,4,5-trimethoxystyrene unit.
    Do CV, Faouzi A, Barette C, Farce A, Fauvarque MO, Colomb E, Catry L, Berthier-Vergnes O, Haftek M, Barret R, Lomberget T.
    Bioorg Med Chem Lett; 2016 Jan 01; 26(1):174-80. PubMed ID: 26602281
    [Abstract] [Full Text] [Related]

  • 12. Antimitotic and vascular disrupting agents: 2-hydroxy-3,4,5-trimethoxybenzophenones.
    Chang CY, Chuang HY, Lee HY, Yeh TK, Kuo CC, Chang CY, Chang JY, Liou JP.
    Eur J Med Chem; 2014 Apr 22; 77():306-14. PubMed ID: 24657567
    [Abstract] [Full Text] [Related]

  • 13. Recent progress in structure-activity relationship studies on the anticancer drug colchicine and its analogues.
    Pan XD, Fang WS.
    Yao Xue Xue Bao; 2002 Oct 22; 37(10):821-7. PubMed ID: 12567870
    [No Abstract] [Full Text] [Related]

  • 14. Cytotoxic Stilbenes and Derivatives as Promising Antimitotic Leads for Cancer Therapy.
    Faustino C, Francisco AP, Isca VMS, Duarte N.
    Curr Pharm Des; 2018 Oct 22; 24(36):4270-4311. PubMed ID: 30636588
    [Abstract] [Full Text] [Related]

  • 15. Structure-activity-relationship studies of conformationally restricted analogs of combretastatin A-4 derived from SU5416.
    Pandit B, Sun Y, Chen P, Sackett DL, Hu Z, Rich W, Li C, Lewis A, Schaefer K, Li PK.
    Bioorg Med Chem; 2006 Oct 01; 14(19):6492-501. PubMed ID: 16860559
    [Abstract] [Full Text] [Related]

  • 16. Rapid synthesis of 4-arylchromenes from ortho-substituted alkynols: A versatile access to restricted isocombretastatin A-4 analogues as antitumor agents.
    Renko D, Provot O, Rasolofonjatovo E, Bignon J, Rodrigo J, Dubois J, Brion JD, Hamze A, Alami M.
    Eur J Med Chem; 2015 Jan 27; 90():834-44. PubMed ID: 25528337
    [Abstract] [Full Text] [Related]

  • 17. Synthesis, biological evaluation of 1,1-diarylethylenes as a novel class of antimitotic agents.
    Hamze A, Giraud A, Messaoudi S, Provot O, Peyrat JF, Bignon J, Liu JM, Wdzieczak-Bakala J, Thoret S, Dubois J, Brion JD, Alami M.
    ChemMedChem; 2009 Nov 27; 4(11):1912-24. PubMed ID: 19790205
    [Abstract] [Full Text] [Related]

  • 18. Interaction of 4-arylcoumarin analogues of combretastatins with microtubule network of HBL100 cells and binding to tubulin.
    Rappl C, Barbier P, Bourgarel-Rey V, Grégoire C, Gilli R, Carre M, Combes S, Finet JP, Peyrot V.
    Biochemistry; 2006 Aug 01; 45(30):9210-8. PubMed ID: 16866367
    [Abstract] [Full Text] [Related]

  • 19. Oxadiazole derivatives as a novel class of antimitotic agents: Synthesis, inhibition of tubulin polymerization, and activity in tumor cell lines.
    Ouyang X, Piatnitski EL, Pattaropong V, Chen X, He HY, Kiselyov AS, Velankar A, Kawakami J, Labelle M, Smith L, Lohman J, Lee SP, Malikzay A, Fleming J, Gerlak J, Wang Y, Rosler RL, Zhou K, Mitelman S, Camara M, Surguladze D, Doody JF, Tuma MC.
    Bioorg Med Chem Lett; 2006 Mar 01; 16(5):1191-6. PubMed ID: 16377187
    [Abstract] [Full Text] [Related]

  • 20. Lead identification of conformationally restricted benzoxepin type combretastatin analogs: synthesis, antiproliferative activity, and tubulin effects.
    Barrett I, Carr M, O'Boyle N, Greene LM, Knox AJ, Lloyd DG, Zisterer DM, Meegan MJ.
    J Enzyme Inhib Med Chem; 2010 Apr 01; 25(2):180-94. PubMed ID: 20222762
    [Abstract] [Full Text] [Related]

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