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Journal Abstract Search

397 related items for PubMed ID: 25475116

  • 1. Suitability Of Nitisinone In Alkaptonuria 1 (SONIA 1): an international, multicentre, randomised, open-label, no-treatment controlled, parallel-group, dose-response study to investigate the effect of once daily nitisinone on 24-h urinary homogentisic acid excretion in patients with alkaptonuria after 4 weeks of treatment.
    Ranganath LR, Milan AM, Hughes AT, Dutton JJ, Fitzgerald R, Briggs MC, Bygott H, Psarelli EE, Cox TF, Gallagher JA, Jarvis JC, van Kan C, Hall AK, Laan D, Olsson B, Szamosi J, Rudebeck M, Kullenberg T, Cronlund A, Svensson L, Junestrand C, Ayoob H, Timmis OG, Sireau N, Le Quan Sang KH, Genovese F, Braconi D, Santucci A, Nemethova M, Zatkova A, McCaffrey J, Christensen P, Ross G, Imrich R, Rovensky J.
    Ann Rheum Dis; 2016 Feb; 75(2):362-7. PubMed ID: 25475116
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  • 8. Clinical and biochemical assessment of depressive symptoms in patients with Alkaptonuria before and after two years of treatment with nitisinone.
    Davison AS, Harrold JA, Hughes G, Norman BP, Devine J, Usher J, Hughes AT, Khedr M, Gallagher JA, Milan AM, J C G H, Ranganath LR.
    Mol Genet Metab; 2018 Sep; 125(1-2):135-143. PubMed ID: 30049652
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  • 10. Ochronotic osteoarthropathy in a mouse model of alkaptonuria, and its inhibition by nitisinone.
    Preston AJ, Keenan CM, Sutherland H, Wilson PJ, Wlodarski B, Taylor AM, Williams DP, Ranganath LR, Gallagher JA, Jarvis JC.
    Ann Rheum Dis; 2014 Jan; 73(1):284-9. PubMed ID: 23511227
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  • 11. Inhibition of para-Hydroxyphenylpyruvate Dioxygenase by Analogues of the Herbicide Nitisinone As a Strategy to Decrease Homogentisic Acid Levels, the Causative Agent of Alkaptonuria.
    Laschi M, Bernardini G, Dreassi E, Millucci L, Geminiani M, Braconi D, Marzocchi B, Botta M, Manetti F, Santucci A.
    ChemMedChem; 2016 Apr 05; 11(7):674-8. PubMed ID: 26947423
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  • 12. Characterizing the alkaptonuria joint and spine phenotype and assessing the effect of homogentisic acid lowering therapy in a large cohort of 87 patients.
    Ranganath LR, Khedr M, Vinjamuri S, Gallagher JA.
    J Inherit Metab Dis; 2021 May 05; 44(3):666-676. PubMed ID: 33452825
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  • 13. Dietary restriction of tyrosine and phenylalanine lowers tyrosinemia associated with nitisinone therapy of alkaptonuria.
    Hughes JH, Wilson PJM, Sutherland H, Judd S, Hughes AT, Milan AM, Jarvis JC, Bou-Gharios G, Ranganath LR, Gallagher JA.
    J Inherit Metab Dis; 2020 Mar 05; 43(2):259-268. PubMed ID: 31503358
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  • 17. A 3-year randomized therapeutic trial of nitisinone in alkaptonuria.
    Introne WJ, Perry MB, Troendle J, Tsilou E, Kayser MA, Suwannarat P, O'Brien KE, Bryant J, Sachdev V, Reynolds JC, Moylan E, Bernardini I, Gahl WA.
    Mol Genet Metab; 2011 Aug 05; 103(4):307-14. PubMed ID: 21620748
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  • 18. Preventive use of nitisinone in alkaptonuria.
    Wolffenbuttel BHR, Heiner-Fokkema MR, van Spronsen FJ.
    Orphanet J Rare Dis; 2021 Aug 03; 16(1):343. PubMed ID: 34344451
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