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198 related items for PubMed ID: 2548593

  • 1. Characterization of free radicals produced during oxidation of etoposide (VP-16) and its catechol and quinone derivatives. An ESR Study.
    Kalyanaraman B, Nemec J, Sinha BK.
    Biochemistry; 1989 May 30; 28(11):4839-46. PubMed ID: 2548593
    [Abstract] [Full Text] [Related]

  • 2. Ascorbate is the primary reductant of the phenoxyl radical of etoposide in the presence of thiols both in cell homogenates and in model systems.
    Kagan VE, Yalowich JC, Day BW, Goldman R, Gantchev TG, Stoyanovsky DA.
    Biochemistry; 1994 Aug 16; 33(32):9651-60. PubMed ID: 8068642
    [Abstract] [Full Text] [Related]

  • 3. Semi-quinone formation from the catechol and ortho-quinone metabolites of the antitumor agent VP-16-213.
    van Maanen JM, Verkerk UH, Broersen J, Lafleur MV, De Vries J, Retèl J, Pinedo HM.
    Free Radic Res Commun; 1988 Aug 16; 4(6):371-84. PubMed ID: 2854106
    [Abstract] [Full Text] [Related]

  • 4. Tyrosinase-induced phenoxyl radicals of etoposide (VP-16): interaction with reductants in model systems, K562 leukemic cell and nuclear homogenates.
    Stoyanovsky D, Yalowich J, Gantchev T, Kagan V.
    Free Radic Res Commun; 1993 Aug 16; 19(6):371-86. PubMed ID: 8168727
    [Abstract] [Full Text] [Related]

  • 5. Antioxidant paradoxes of phenolic compounds: peroxyl radical scavenger and lipid antioxidant, etoposide (VP-16), inhibits sarcoplasmic reticulum Ca(2+)-ATPase via thiol oxidation by its phenoxyl radical.
    Ritov VB, Goldman R, Stoyanovsky DA, Menshikova EV, Kagan VE.
    Arch Biochem Biophys; 1995 Aug 01; 321(1):140-52. PubMed ID: 7639514
    [Abstract] [Full Text] [Related]

  • 6. Characterization of semiquinone free radicals formed from stilbene catechol estrogens. An ESR spin stabilization and spin trapping study.
    Kalyanaraman B, Sealy RC, Liehr JG.
    J Biol Chem; 1989 Jul 05; 264(19):11014-9. PubMed ID: 2544580
    [Abstract] [Full Text] [Related]

  • 7. Inhibition of Na+/K(+)-ATPase by phenoxyl radicals of etoposide (VP-16): role of sulfhydryls oxidation.
    Kurella EG, Osipov AN, Goldman R, Boldyrev AA, Kagan VE.
    Biochim Biophys Acta; 1995 Nov 21; 1232(1-2):52-8. PubMed ID: 7495837
    [Abstract] [Full Text] [Related]

  • 8. Role of the semi-quinone free radical of the anti-tumour agent etoposide (VP-16-213) in the inactivation of single- and double-stranded phi X174 DNA.
    Mans DR, Retèl J, van Maanen JM, Lafleur MV, van Schaik MA, Pinedo HM, Lankelma J.
    Br J Cancer; 1990 Jul 21; 62(1):54-60. PubMed ID: 2167725
    [Abstract] [Full Text] [Related]

  • 9. Effects of the ortho-quinone and catechol of the antitumor drug VP-16-213 on the biological activity of single-stranded and double-stranded phi X174 DNA.
    van Maanen JM, Lafleur MV, Mans DR, van den Akker E, de Ruiter C, Kootstra PR, Pappie D, de Vries J, Retèl J, Pinedo HM.
    Biochem Pharmacol; 1988 Oct 01; 37(19):3579-89. PubMed ID: 2972290
    [Abstract] [Full Text] [Related]

  • 10. Reactions of glutathione with the catechol, the ortho-quinone and the semi-quinone free radical of etoposide. Consequences for DNA inactivation.
    Mans DR, Lafleur MV, Westmijze EJ, Horn IR, Bets D, Schuurhuis GJ, Lankelma J, Retèl J.
    Biochem Pharmacol; 1992 Apr 15; 43(8):1761-8. PubMed ID: 1315544
    [Abstract] [Full Text] [Related]

  • 11. Reaction between ortho-semiquinones and oxygen: pulse radiolysis, electron spin resonance, and oxygen uptake studies.
    Kalyanaraman B, Korytowski W, Pilas B, Sarna T, Land EJ, Truscott TG.
    Arch Biochem Biophys; 1988 Oct 15; 266(1):277-84. PubMed ID: 2845864
    [Abstract] [Full Text] [Related]

  • 12. Tyrosinase-catalyzed oxidation of dopa and related catechol(amine)s: a kinetic electron spin resonance investigation using spin-stabilization and spin label oximetry.
    Korytowski W, Sarna T, Kalyanaraman B, Sealy RC.
    Biochim Biophys Acta; 1987 Jun 22; 924(3):383-92. PubMed ID: 3036239
    [Abstract] [Full Text] [Related]

  • 13. An electron spin resonance study of o-semiquinones formed during the enzymatic and autoxidation of catechol estrogens.
    Kalyanaraman B, Sealy RC, Sivarajah K.
    J Biol Chem; 1984 Nov 25; 259(22):14018-22. PubMed ID: 6094535
    [Abstract] [Full Text] [Related]

  • 14. Phenoxyl radicals of etoposide (VP-16) can directly oxidize intracellular thiols: protective versus damaging effects of phenolic antioxidants.
    Tyurina YY, Tyurin VA, Yalowich JC, Quinn PJ, Claycamp HG, Schor NF, Pitt BR, Kagan VE.
    Toxicol Appl Pharmacol; 1995 Apr 25; 131(2):277-88. PubMed ID: 7716769
    [Abstract] [Full Text] [Related]

  • 15. Oxidation of the substituted catechols dihydroxyphenylalanine methyl ester and trihydroxyphenylalanine by lactoperoxidase and its compounds.
    Metodiewa D, Reszka K, Dunford HB.
    Arch Biochem Biophys; 1989 Nov 01; 274(2):601-8. PubMed ID: 2552928
    [Abstract] [Full Text] [Related]

  • 16. Semiquinone anion radicals from addition of amino acids, peptides, and proteins to quinones derived from oxidation of catechols and catecholamines. An ESR spin stabilization study.
    Kalyanaraman B, Premovic PI, Sealy RC.
    J Biol Chem; 1987 Aug 15; 262(23):11080-7. PubMed ID: 3038907
    [Abstract] [Full Text] [Related]

  • 17. Iron-dependent hydroxyl radical formation and DNA damage from a novel metabolite of the clinically active antitumor drug VP-16.
    Sinha BK, Eliot HM, Kalayanaraman B.
    FEBS Lett; 1988 Jan 25; 227(2):240-4. PubMed ID: 2828121
    [Abstract] [Full Text] [Related]

  • 18. Electron spin resonance--spin stabilization in enzymatic systems: detection of semiquinones produced during peroxidatic oxidation of catechols and catecholamines.
    Kalyanaraman B, Sealy RC.
    Biochem Biophys Res Commun; 1982 Jun 30; 106(4):1119-25. PubMed ID: 6288039
    [No Abstract] [Full Text] [Related]

  • 19. ESR identification of free radicals formed from the oxidation of catechol estrogens by Cu2+.
    Seacat AM, Kuppusamy P, Zweier JL, Yager JD.
    Arch Biochem Biophys; 1997 Nov 01; 347(1):45-52. PubMed ID: 9344463
    [Abstract] [Full Text] [Related]

  • 20. Pro-oxidant and antioxidant mechanisms of etoposide in HL-60 cells: role of myeloperoxidase.
    Kagan VE, Kuzmenko AI, Tyurina YY, Shvedova AA, Matsura T, Yalowich JC.
    Cancer Res; 2001 Nov 01; 61(21):7777-84. PubMed ID: 11691792
    [Abstract] [Full Text] [Related]


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