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658 related items for PubMed ID: 25492967

  • 1. The kinase Itk and the adaptor TSAd change the specificity of the kinase Lck in T cells by promoting the phosphorylation of Tyr192.
    Granum S, Sundvold-Gjerstad V, Gopalakrishnan RP, Berge T, Koll L, Abrahamsen G, Sørlie M, Spurkland A.
    Sci Signal; 2014 Dec 09; 7(355):ra118. PubMed ID: 25492967
    [Abstract] [Full Text] [Related]

  • 2. The SH3 domains of the protein kinases ITK and LCK compete for adjacent sites on T cell-specific adapter protein.
    Andersen TCB, Kristiansen PE, Huszenicza Z, Johansson MU, Gopalakrishnan RP, Kjelstrup H, Boyken S, Sundvold-Gjerstad V, Granum S, Sørli M, Backe PH, Fulton DB, Karlsson BG, Andreotti AH, Spurkland A.
    J Biol Chem; 2019 Oct 18; 294(42):15480-15494. PubMed ID: 31484725
    [Abstract] [Full Text] [Related]

  • 3. T cell-specific adapter protein inhibits T cell activation by modulating Lck activity.
    Sundvold V, Torgersen KM, Post NH, Marti F, King PD, Røttingen JA, Spurkland A, Lea T.
    J Immunol; 2000 Sep 15; 165(6):2927-31. PubMed ID: 10975797
    [Abstract] [Full Text] [Related]

  • 4. pp56Lck mediates TCR zeta-chain binding to the microfilament cytoskeleton.
    Rozdzial MM, Pleiman CM, Cambier JC, Finkel TH.
    J Immunol; 1998 Nov 15; 161(10):5491-9. PubMed ID: 9820525
    [Abstract] [Full Text] [Related]

  • 5. Efficient CD28 signalling leads to increases in the kinase activities of the TEC family tyrosine kinase EMT/ITK/TSK and the SRC family tyrosine kinase LCK.
    Gibson S, Truitt K, Lu Y, Lapushin R, Khan H, Imboden JB, Mills GB.
    Biochem J; 1998 Mar 15; 330 ( Pt 3)(Pt 3):1123-8. PubMed ID: 9494076
    [Abstract] [Full Text] [Related]

  • 6. Roles of Lck, Syk and ZAP-70 tyrosine kinases in TCR-mediated phosphorylation of the adapter protein Shc.
    Walk SF, March ME, Ravichandran KS.
    Eur J Immunol; 1998 Aug 15; 28(8):2265-75. PubMed ID: 9710204
    [Abstract] [Full Text] [Related]

  • 7. The EMT/ITK/TSK (EMT) tyrosine kinase is activated during TCR signaling: LCK is required for optimal activation of EMT.
    Gibson S, August A, Kawakami Y, Kawakami T, Dupont B, Mills GB.
    J Immunol; 1996 Apr 15; 156(8):2716-22. PubMed ID: 8609388
    [Abstract] [Full Text] [Related]

  • 8. Modulation of Lck function through multisite docking to T cell-specific adapter protein.
    Granum S, Andersen TC, Sørlie M, Jørgensen M, Koll L, Berge T, Lea T, Fleckenstein B, Spurkland A, Sundvold-Gjerstad V.
    J Biol Chem; 2008 Aug 08; 283(32):21909-19. PubMed ID: 18541536
    [Abstract] [Full Text] [Related]

  • 9. Essential role of the T cell-specific adapter protein in the activation of LCK in peripheral T cells.
    Marti F, Garcia GG, Lapinski PE, MacGregor JN, King PD.
    J Exp Med; 2006 Feb 20; 203(2):281-7. PubMed ID: 16446380
    [Abstract] [Full Text] [Related]

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  • 13. Lad, an adapter protein interacting with the SH2 domain of p56lck, is required for T cell activation.
    Choi YB, Kim CK, Yun Y.
    J Immunol; 1999 Nov 15; 163(10):5242-9. PubMed ID: 10553045
    [Abstract] [Full Text] [Related]

  • 14. Inhibitory effects of rosmarinic acid on Lck SH2 domain binding to a synthetic phosphopeptide.
    Ahn SC, Oh WK, Kim BY, Kang DO, Kim MS, Heo GY, Ahn JS.
    Planta Med; 2003 Jul 15; 69(7):642-6. PubMed ID: 12898421
    [Abstract] [Full Text] [Related]

  • 15. Tyrosine phosphorylation of adaptor protein 3BP2 induces T cell receptor-mediated activation of transcription factor.
    Qu X, Kawauchi-Kamata K, Miah SM, Hatani T, Yamamura H, Sada K.
    Biochemistry; 2005 Mar 15; 44(10):3891-8. PubMed ID: 15751964
    [Abstract] [Full Text] [Related]

  • 16. T cell activation at the immunological synapse: vesicles emerge for LATer signaling.
    Billadeau DD.
    Sci Signal; 2010 May 11; 3(121):pe16. PubMed ID: 20460646
    [Abstract] [Full Text] [Related]

  • 17. Tyrosine 192 within the SH2 domain of the Src-protein tyrosine kinase p56Lck regulates T-cell activation independently of Lck/CD45 interactions.
    Kästle M, Merten C, Hartig R, Kaehne T, Liaunardy-Jopeace A, Woessner NM, Schamel WW, James J, Minguet S, Simeoni L, Schraven B.
    Cell Commun Signal; 2020 Nov 23; 18(1):183. PubMed ID: 33225946
    [Abstract] [Full Text] [Related]

  • 18. T cell receptor signal initiation induced by low-grade stimulation requires the cooperation of LAT in human T cells.
    Dong S, Corre B, Nika K, Pellegrini S, Michel F.
    PLoS One; 2010 Nov 30; 5(11):e15114. PubMed ID: 21152094
    [Abstract] [Full Text] [Related]

  • 19. A weak Lck tail bite is necessary for Lck function in T cell antigen receptor signaling.
    Nika K, Tautz L, Arimura Y, Vang T, Williams S, Mustelin T.
    J Biol Chem; 2007 Dec 07; 282(49):36000-9. PubMed ID: 17897955
    [Abstract] [Full Text] [Related]

  • 20. A molecular framework for two-step T cell signaling: Lck Src homology 3 mutations discriminate distinctly regulated lipid raft reorganization events.
    Patel VP, Moran M, Low TA, Miceli MC.
    J Immunol; 2001 Jan 15; 166(2):754-64. PubMed ID: 11145647
    [Abstract] [Full Text] [Related]

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