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Journal Abstract Search


657 related items for PubMed ID: 25514599

  • 1. PKM2 promotes metastasis by recruiting myeloid-derived suppressor cells and indicates poor prognosis for hepatocellular carcinoma.
    Liu WR, Tian MX, Yang LX, Lin YL, Jin L, Ding ZB, Shen YH, Peng YF, Gao DM, Zhou J, Qiu SJ, Dai Z, He R, Fan J, Shi YH.
    Oncotarget; 2015 Jan 20; 6(2):846-61. PubMed ID: 25514599
    [Abstract] [Full Text] [Related]

  • 2. Pyruvate kinase M2 prevents apoptosis via modulating Bim stability and associates with poor outcome in hepatocellular carcinoma.
    Hu W, Lu SX, Li M, Zhang C, Liu LL, Fu J, Jin JT, Luo RZ, Zhang CZ, Yun JP.
    Oncotarget; 2015 Mar 30; 6(9):6570-83. PubMed ID: 25788265
    [Abstract] [Full Text] [Related]

  • 3. Switching of pyruvate kinase isoform L to M2 promotes metabolic reprogramming in hepatocarcinogenesis.
    Wong CC, Au SL, Tse AP, Xu IM, Lai RK, Chiu DK, Wei LL, Fan DN, Tsang FH, Lo RC, Wong CM, Ng IO.
    PLoS One; 2014 Mar 30; 9(12):e115036. PubMed ID: 25541689
    [Abstract] [Full Text] [Related]

  • 4. Mechanisms of pyruvate kinase M2 isoform inhibits cell motility in hepatocellular carcinoma cells.
    Chen YL, Song JJ, Chen XC, Xu W, Zhi Q, Liu YP, Xu HZ, Pan JS, Ren JL, Guleng B.
    World J Gastroenterol; 2015 Aug 14; 21(30):9093-102. PubMed ID: 26290635
    [Abstract] [Full Text] [Related]

  • 5. HSP90 promotes cell glycolysis, proliferation and inhibits apoptosis by regulating PKM2 abundance via Thr-328 phosphorylation in hepatocellular carcinoma.
    Xu Q, Tu J, Dou C, Zhang J, Yang L, Liu X, Lei K, Liu Z, Wang Y, Li L, Bao H, Wang J, Tu K.
    Mol Cancer; 2017 Dec 20; 16(1):178. PubMed ID: 29262861
    [Abstract] [Full Text] [Related]

  • 6. LNCAROD enhances hepatocellular carcinoma malignancy by activating glycolysis through induction of pyruvate kinase isoform PKM2.
    Jia G, Wang Y, Lin C, Lai S, Dai H, Wang Z, Dai L, Su H, Song Y, Zhang N, Feng Y, Tang B.
    J Exp Clin Cancer Res; 2021 Sep 22; 40(1):299. PubMed ID: 34551796
    [Abstract] [Full Text] [Related]

  • 7. Co-expression of PKM2 and TRIM35 predicts survival and recurrence in hepatocellular carcinoma.
    Chen Z, Lu X, Wang Z, Jin G, Wang Q, Chen D, Chen T, Li J, Fan J, Cong W, Gao Q, He X.
    Oncotarget; 2015 Feb 10; 6(4):2538-48. PubMed ID: 25576919
    [Abstract] [Full Text] [Related]

  • 8. miR-4417 Targets Tripartite Motif-Containing 35 (TRIM35) and Regulates Pyruvate Kinase Muscle 2 (PKM2) Phosphorylation to Promote Proliferation and Suppress Apoptosis in Hepatocellular Carcinoma Cells.
    Song L, Zhang W, Chang Z, Pan Y, Zong H, Fan Q, Wang L.
    Med Sci Monit; 2017 Apr 10; 23():1741-1750. PubMed ID: 28394882
    [Abstract] [Full Text] [Related]

  • 9. MicroRNA-122 affects cell aggressiveness and apoptosis by targeting PKM2 in human hepatocellular carcinoma.
    Xu Q, Zhang M, Tu J, Pang L, Cai W, Liu X.
    Oncol Rep; 2015 Oct 10; 34(4):2054-64. PubMed ID: 26252254
    [Abstract] [Full Text] [Related]

  • 10. Oviductus ranae protein hydrolysate (ORPH) inhibits the growth, metastasis and glycolysis of HCC by targeting miR-491-5p/PKM2 axis.
    Xu Q, Dou C, Liu X, Yang L, Ni C, Wang J, Guo Y, Yang W, Tong X, Huang D.
    Biomed Pharmacother; 2018 Nov 10; 107():1692-1704. PubMed ID: 30257387
    [Abstract] [Full Text] [Related]

  • 11. Homeobox B9 is overexpressed in hepatocellular carcinomas and promotes tumor cell proliferation both in vitro and in vivo.
    Li F, Dong L, Xing R, Wang L, Luan F, Yao C, Ji X, Bai L.
    Biochem Biophys Res Commun; 2014 Feb 07; 444(2):241-7. PubMed ID: 24462859
    [Abstract] [Full Text] [Related]

  • 12. miR-122 targets pyruvate kinase M2 and affects metabolism of hepatocellular carcinoma.
    Liu AM, Xu Z, Shek FH, Wong KF, Lee NP, Poon RT, Chen J, Luk JM.
    PLoS One; 2014 Feb 07; 9(1):e86872. PubMed ID: 24466275
    [Abstract] [Full Text] [Related]

  • 13. COX-2 induces apoptosis-resistance in hepatocellular carcinoma cells via the HIF-1α/PKM2 pathway.
    Wang Q, Lu D, Fan L, Li Y, Liu Y, Yu H, Wang H, Liu J, Sun G.
    Int J Mol Med; 2019 Jan 07; 43(1):475-488. PubMed ID: 30365092
    [Abstract] [Full Text] [Related]

  • 14. Effects of PKM2 on global metabolic changes and prognosis in hepatocellular carcinoma: from gene expression to drug discovery.
    Lv WW, Liu D, Liu XC, Feng TN, Li L, Qian BY, Li WX.
    BMC Cancer; 2018 Nov 21; 18(1):1150. PubMed ID: 30463528
    [Abstract] [Full Text] [Related]

  • 15. Ectosomal PKM2 Promotes HCC by Inducing Macrophage Differentiation and Remodeling the Tumor Microenvironment.
    Hou PP, Luo LJ, Chen HZ, Chen QT, Bian XL, Wu SF, Zhou JX, Zhao WX, Liu JM, Wang XM, Zhang ZY, Yao LM, Chen Q, Zhou D, Wu Q.
    Mol Cell; 2020 Jun 18; 78(6):1192-1206.e10. PubMed ID: 32470318
    [Abstract] [Full Text] [Related]

  • 16. Overexpression of CXCL5 mediates neutrophil infiltration and indicates poor prognosis for hepatocellular carcinoma.
    Zhou SL, Dai Z, Zhou ZJ, Wang XY, Yang GH, Wang Z, Huang XW, Fan J, Zhou J.
    Hepatology; 2012 Dec 18; 56(6):2242-54. PubMed ID: 22711685
    [Abstract] [Full Text] [Related]

  • 17. mTORC1 Up-Regulates GP73 to Promote Proliferation and Migration of Hepatocellular Carcinoma Cells and Growth of Xenograft Tumors in Mice.
    Chen X, Wang Y, Tao J, Shi Y, Gai X, Huang F, Ma Q, Zhou Z, Chen H, Zhang H, Liu Z, Sun Q, Peng H, Chen R, Jing Y, Yang H, Mao Y, Zhang H.
    Gastroenterology; 2015 Sep 18; 149(3):741-52.e14. PubMed ID: 25980751
    [Abstract] [Full Text] [Related]

  • 18. E3 ligase ZFP91 inhibits Hepatocellular Carcinoma Metabolism Reprogramming by regulating PKM splicing.
    Chen D, Wang Y, Lu R, Jiang X, Chen X, Meng N, Chen M, Xie S, Yan GR.
    Theranostics; 2020 Sep 18; 10(19):8558-8572. PubMed ID: 32754263
    [Abstract] [Full Text] [Related]

  • 19. Ack1 overexpression promotes metastasis and indicates poor prognosis of hepatocellular carcinoma.
    Lei X, Li YF, Chen GD, Ou DP, Qiu XX, Zuo CH, Yang LY.
    Oncotarget; 2015 Dec 01; 6(38):40622-41. PubMed ID: 26536663
    [Abstract] [Full Text] [Related]

  • 20. Pyruvate Kinase M2 Modulates Esophageal Squamous Cell Carcinoma Chemotherapy Response by Regulating the Pentose Phosphate Pathway.
    Fukuda S, Miyata H, Miyazaki Y, Makino T, Takahashi T, Kurokawa Y, Yamasaki M, Nakajima K, Takiguchi S, Mori M, Doki Y.
    Ann Surg Oncol; 2015 Dec 01; 22 Suppl 3():S1461-8. PubMed ID: 25808097
    [Abstract] [Full Text] [Related]


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