These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

322 related items for PubMed ID: 25515955

  • 1. Design, synthesis and structure-activity relationship studies of novel sirtuin 2 (SIRT2) inhibitors with a benzamide skeleton.
    Sakai T, Matsumoto Y, Ishikawa M, Sugita K, Hashimoto Y, Wakai N, Kitao A, Morishita E, Toyoshima C, Hayashi T, Akiyama T.
    Bioorg Med Chem; 2015 Jan 15; 23(2):328-39. PubMed ID: 25515955
    [Abstract] [Full Text] [Related]

  • 2. Hit-to-lead optimization on aryloxybenzamide derivative virtual screening hit against SIRT.
    Yagci S, Gozelle M, Kaya SG, Ozkan Y, Aksel AB, Bakar-Ates F, Dundar Y, Eren G.
    Bioorg Med Chem; 2021 Jan 15; 30():115961. PubMed ID: 33360574
    [Abstract] [Full Text] [Related]

  • 3. Virtual screening approach of sirtuin inhibitors results in two new scaffolds.
    Kokkonen P, Kokkola T, Suuronen T, Poso A, Jarho E, Lahtela-Kakkonen M.
    Eur J Pharm Sci; 2015 Aug 30; 76():27-32. PubMed ID: 25936698
    [Abstract] [Full Text] [Related]

  • 4. Identification of a sirtuin 3 inhibitor that displays selectivity over sirtuin 1 and 2.
    Galli U, Mesenzani O, Coppo C, Sorba G, Canonico PL, Tron GC, Genazzani AA.
    Eur J Med Chem; 2012 Sep 30; 55():58-66. PubMed ID: 22835719
    [Abstract] [Full Text] [Related]

  • 5. Design, synthesis, in-vitro evaluation and molecular docking studies of novel indole derivatives as inhibitors of SIRT1 and SIRT2.
    Manjula R, Gokhale N, Unni S, Deshmukh P, Reddyrajula R, Srinivas Bharath MM, Dalimba U, Padmanabhan B.
    Bioorg Chem; 2019 Nov 30; 92():103281. PubMed ID: 31561106
    [Abstract] [Full Text] [Related]

  • 6. Design, synthesis, and biological activity of a novel series of human sirtuin-2-selective inhibitors.
    Suzuki T, Khan MN, Sawada H, Imai E, Itoh Y, Yamatsuta K, Tokuda N, Takeuchi J, Seko T, Nakagawa H, Miyata N.
    J Med Chem; 2012 Jun 28; 55(12):5760-73. PubMed ID: 22642300
    [Abstract] [Full Text] [Related]

  • 7. Discovery of bicyclic pyrazoles as class III histone deacetylase SIRT1 and SIRT2 inhibitors.
    Therrien E, Larouche G, Nguyen N, Rahil J, Lemieux AM, Li Z, Fournel M, Yan TP, Landry AJ, Lefebvre S, Wang JJ, MacBeth K, Heise C, Nguyen A, Besterman JM, Déziel R, Wahhab A.
    Bioorg Med Chem Lett; 2015 Jun 15; 25(12):2514-8. PubMed ID: 25971769
    [Abstract] [Full Text] [Related]

  • 8. Discovery of New SIRT2 Inhibitors by Utilizing a Consensus Docking/Scoring Strategy and Structure-Activity Relationship Analysis.
    Huang S, Song C, Wang X, Zhang G, Wang Y, Jiang X, Sun Q, Huang L, Xiang R, Hu Y, Li L, Yang S.
    J Chem Inf Model; 2017 Apr 24; 57(4):669-679. PubMed ID: 28301150
    [Abstract] [Full Text] [Related]

  • 9. Tetrahydroindoles as Multipurpose Screening Compounds and Novel Sirtuin Inhibitors.
    Vojacek S, Schulig L, Wössner N, Geist N, Langel W, Jung M, Schade D, Link A.
    ChemMedChem; 2019 Apr 17; 14(8):853-864. PubMed ID: 30811852
    [Abstract] [Full Text] [Related]

  • 10. 3-(N-arylsulfamoyl)benzamides, inhibitors of human sirtuin type 2 (SIRT2).
    Choi SH, Quinti L, Kazantsev AG, Silverman RB.
    Bioorg Med Chem Lett; 2012 Apr 15; 22(8):2789-93. PubMed ID: 22446090
    [Abstract] [Full Text] [Related]

  • 11. Design, Synthesis, and Biological Evaluation of 8-Mercapto-3,7-Dihydro-1H-Purine-2,6-Diones as Potent Inhibitors of SIRT1, SIRT2, SIRT3, and SIRT5.
    Han H, Li C, Li M, Yang L, Zhao S, Wang Z, Liu H, Liu D.
    Molecules; 2020 Jun 15; 25(12):. PubMed ID: 32549218
    [Abstract] [Full Text] [Related]

  • 12. Identification of Diketopiperazine-Containing 2-Anilinobenzamides as Potent Sirtuin 2 (SIRT2)-Selective Inhibitors Targeting the "Selectivity Pocket", Substrate-Binding Site, and NAD+-Binding Site.
    Mellini P, Itoh Y, Elboray EE, Tsumoto H, Li Y, Suzuki M, Takahashi Y, Tojo T, Kurohara T, Miyake Y, Miura Y, Kitao Y, Kotoku M, Iida T, Suzuki T.
    J Med Chem; 2019 Jun 27; 62(12):5844-5862. PubMed ID: 31144814
    [Abstract] [Full Text] [Related]

  • 13. Synthesis and evaluation of novel benzimidazole derivatives as sirtuin inhibitors with antitumor activities.
    Yoon YK, Ali MA, Wei AC, Choon TS, Osman H, Parang K, Shirazi AN.
    Bioorg Med Chem; 2014 Jan 15; 22(2):703-10. PubMed ID: 24387981
    [Abstract] [Full Text] [Related]

  • 14. Structure-based design of pseudopeptidic inhibitors for SIRT1 and SIRT2.
    Huhtiniemi T, Salo HS, Suuronen T, Poso A, Salminen A, Leppänen J, Jarho E, Lahtela-Kakkonen M.
    J Med Chem; 2011 Oct 13; 54(19):6456-68. PubMed ID: 21895016
    [Abstract] [Full Text] [Related]

  • 15. Synthesis and Evaluation of Novel Benzofuran Derivatives as Selective SIRT2 Inhibitors.
    Zhou Y, Cui H, Yu X, Peng T, Wang G, Wen X, Sun Y, Liu S, Zhang S, Hu L, Wang L.
    Molecules; 2017 Aug 14; 22(8):. PubMed ID: 28805748
    [Abstract] [Full Text] [Related]

  • 16. Discovery of 2-((4,6-dimethylpyrimidin-2-yl)thio)-N-phenylacetamide derivatives as new potent and selective human sirtuin 2 inhibitors.
    Yang L, Ma X, Yuan C, He Y, Li L, Fang S, Xia W, He T, Qian S, Xu Z, Li G, Wang Z.
    Eur J Med Chem; 2017 Jul 07; 134():230-241. PubMed ID: 28415012
    [Abstract] [Full Text] [Related]

  • 17. Discovery and characterization of small molecule SIRT3-specific inhibitors as revealed by mass spectrometry.
    Loharch S, Chhabra S, Kumar A, Swarup S, Parkesh R.
    Bioorg Chem; 2021 May 07; 110():104768. PubMed ID: 33676042
    [Abstract] [Full Text] [Related]

  • 18. Benzimidazoles as new scaffold of sirtuin inhibitors: green synthesis, in vitro studies, molecular docking analysis and evaluation of their anti-cancer properties.
    Yoon YK, Ali MA, Wei AC, Shirazi AN, Parang K, Choon TS.
    Eur J Med Chem; 2014 Aug 18; 83():448-54. PubMed ID: 24992072
    [Abstract] [Full Text] [Related]

  • 19. Synthesis of certain benzothieno[3,2-d]pyrimidine derivatives as a selective SIRT2 inhibitors.
    Khalil NA, Ahmed EM, Zaher AF, El-Zoghbi MS, Sobh EA.
    Eur J Med Chem; 2020 Feb 01; 187():111926. PubMed ID: 31812033
    [Abstract] [Full Text] [Related]

  • 20. The Fungal Metabolite Eurochevalierine, a Sequiterpene Alkaloid, Displays Anti-Cancer Properties through Selective Sirtuin 1/2 Inhibition.
    Schnekenburger M, Mathieu V, Lefranc F, Jang JY, Masi M, Kijjoa A, Evidente A, Kim HJ, Kiss R, Dicato M, Han BW, Diederich M.
    Molecules; 2018 Feb 05; 23(2):. PubMed ID: 29401749
    [Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 17.