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398 related items for PubMed ID: 25522273

  • 1. Mitochondrial inhibitor sensitizes non-small-cell lung carcinoma cells to TRAIL-induced apoptosis by reactive oxygen species and Bcl-X(L)/p53-mediated amplification mechanisms.
    Shi YL, Feng S, Chen W, Hua ZC, Bian JJ, Yin W.
    Cell Death Dis; 2014 Dec 18; 5(12):e1579. PubMed ID: 25522273
    [Abstract] [Full Text] [Related]

  • 2. Inhibition of Cathepsin S Induces Mitochondrial ROS That Sensitizes TRAIL-Mediated Apoptosis Through p53-Mediated Downregulation of Bcl-2 and c-FLIP.
    Seo BR, Min KJ, Woo SM, Choe M, Choi KS, Lee YK, Yoon G, Kwon TK.
    Antioxid Redox Signal; 2017 Aug 01; 27(4):215-233. PubMed ID: 27927016
    [Abstract] [Full Text] [Related]

  • 3. Wogonin enhances antitumor activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo through ROS-mediated downregulation of cFLIPL and IAP proteins.
    Yang L, Wang Q, Li D, Zhou Y, Zheng X, Sun H, Yan J, Zhang L, Lin Y, Wang X.
    Apoptosis; 2013 May 01; 18(5):618-26. PubMed ID: 23371323
    [Abstract] [Full Text] [Related]

  • 4. CCAAT/enhancer binding protein homologous protein-dependent death receptor 5 induction and ubiquitin/proteasome-mediated cellular FLICE-inhibitory protein down-regulation contribute to enhancement of tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by dimethyl-celecoxib in human non small-cell lung cancer cells.
    Chen S, Liu X, Yue P, Schönthal AH, Khuri FR, Sun SY.
    Mol Pharmacol; 2007 Nov 01; 72(5):1269-79. PubMed ID: 17684158
    [Abstract] [Full Text] [Related]

  • 5. Nutlin-3, a small-molecule MDM2 inhibitor, sensitizes Caki cells to TRAIL-induced apoptosis through p53-mediated PUMA upregulation and ROS-mediated DR5 upregulation.
    Park EJ, Choi KS, Yoo YH, Kwon TK.
    Anticancer Drugs; 2013 Mar 01; 24(3):260-9. PubMed ID: 23187459
    [Abstract] [Full Text] [Related]

  • 6. Compound C sensitizes Caki renal cancer cells to TRAIL-induced apoptosis through reactive oxygen species-mediated down-regulation of c-FLIPL and Mcl-1.
    Jang JH, Lee TJ, Yang ES, Min do S, Kim YH, Kim SH, Choi YH, Park JW, Choi KS, Kwon TK.
    Exp Cell Res; 2010 Aug 01; 316(13):2194-203. PubMed ID: 20451517
    [Abstract] [Full Text] [Related]

  • 7. 6-Shogaol enhances renal carcinoma Caki cells to TRAIL-induced apoptosis through reactive oxygen species-mediated cytochrome c release and down-regulation of c-FLIP(L) expression.
    Han MA, Woo SM, Min KJ, Kim S, Park JW, Kim DE, Kim SH, Choi YH, Kwon TK.
    Chem Biol Interact; 2015 Feb 25; 228():69-78. PubMed ID: 25619640
    [Abstract] [Full Text] [Related]

  • 8. Reactive oxygen species regulate caspase activation in tumor necrosis factor-related apoptosis-inducing ligand-resistant human colon carcinoma cell lines.
    Izeradjene K, Douglas L, Tillman DM, Delaney AB, Houghton JA.
    Cancer Res; 2005 Aug 15; 65(16):7436-45. PubMed ID: 16103097
    [Abstract] [Full Text] [Related]

  • 9. Depletion of end-binding protein 1 (EB1) promotes apoptosis of human non-small-cell lung cancer cells via reactive oxygen species and Bax-mediated mitochondrial dysfunction.
    Kim MJ, Yun HS, Hong EH, Lee SJ, Baek JH, Lee CW, Yim JH, Kim JS, Park JK, Um HD, Hwang SG.
    Cancer Lett; 2013 Oct 01; 339(1):15-24. PubMed ID: 23900080
    [Abstract] [Full Text] [Related]

  • 10. The caspase-8/Bid/cytochrome c axis links signals from death receptors to mitochondrial reactive oxygen species production.
    Kim WS, Lee KS, Kim JH, Kim CK, Lee G, Choe J, Won MH, Kim TH, Jeoung D, Lee H, Kim JY, Ae Jeong M, Ha KS, Kwon YG, Kim YM.
    Free Radic Biol Med; 2017 Nov 01; 112():567-577. PubMed ID: 28888620
    [Abstract] [Full Text] [Related]

  • 11. Berberine sensitizes TRAIL-induced apoptosis through proteasome-mediated downregulation of c-FLIP and Mcl-1 proteins.
    Lee SJ, Noh HJ, Sung EG, Song IH, Kim JY, Kwon TK, Lee TJ.
    Int J Oncol; 2011 Feb 01; 38(2):485-92. PubMed ID: 21170508
    [Abstract] [Full Text] [Related]

  • 12. Rosiglitazone promotes tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by reactive oxygen species-mediated up-regulation of death receptor 5 and down-regulation of c-FLIP.
    Kim YH, Jung EM, Lee TJ, Kim SH, Choi YH, Park JW, Park JW, Choi KS, Kwon TK.
    Free Radic Biol Med; 2008 Mar 15; 44(6):1055-68. PubMed ID: 18164688
    [Abstract] [Full Text] [Related]

  • 13. The proteasome inhibitor PS-341 (bortezomib) up-regulates DR5 expression leading to induction of apoptosis and enhancement of TRAIL-induced apoptosis despite up-regulation of c-FLIP and survivin expression in human NSCLC cells.
    Liu X, Yue P, Chen S, Hu L, Lonial S, Khuri FR, Sun SY.
    Cancer Res; 2007 May 15; 67(10):4981-8. PubMed ID: 17510429
    [Abstract] [Full Text] [Related]

  • 14. Carnosic acid sensitized TRAIL-mediated apoptosis through down-regulation of c-FLIP and Bcl-2 expression at the post translational levels and CHOP-dependent up-regulation of DR5, Bim, and PUMA expression in human carcinoma caki cells.
    Jung KJ, Min KJ, Bae JH, Kwon TK.
    Oncotarget; 2015 Jan 30; 6(3):1556-68. PubMed ID: 25596735
    [Abstract] [Full Text] [Related]

  • 15. Apigenin potentiates TRAIL therapy of non-small cell lung cancer via upregulating DR4/DR5 expression in a p53-dependent manner.
    Chen M, Wang X, Zha D, Cai F, Zhang W, He Y, Huang Q, Zhuang H, Hua ZC.
    Sci Rep; 2016 Oct 18; 6():35468. PubMed ID: 27752089
    [Abstract] [Full Text] [Related]

  • 16. Suppression of HSP70 expression sensitizes NSCLC cell lines to TRAIL-induced apoptosis by upregulating DR4 and DR5 and downregulating c-FLIP-L expressions.
    Zhuang H, Jiang W, Zhang X, Qiu F, Gan Z, Cheng W, Zhang J, Guan S, Tang B, Huang Q, Wu X, Huang X, Jiang W, Hu Q, Lu M, Hua ZC.
    J Mol Med (Berl); 2013 Feb 18; 91(2):219-35. PubMed ID: 22948392
    [Abstract] [Full Text] [Related]

  • 17. Resveratrol sensitizes lung cancer cell to TRAIL by p53 independent and suppression of Akt/NF-κB signaling.
    Rasheduzzaman M, Jeong JK, Park SY.
    Life Sci; 2018 Sep 01; 208():208-220. PubMed ID: 30031063
    [Abstract] [Full Text] [Related]

  • 18. Imatinib enhances human melanoma cell susceptibility to TRAIL-induced cell death: Relationship to Bcl-2 family and caspase activation.
    Hamaï A, Richon C, Meslin F, Faure F, Kauffmann A, Lecluse Y, Jalil A, Larue L, Avril MF, Chouaib S, Mehrpour M.
    Oncogene; 2006 Dec 07; 25(58):7618-34. PubMed ID: 16983347
    [Abstract] [Full Text] [Related]

  • 19. Sensitization of tumor cells to Apo2 ligand/TRAIL-induced apoptosis by inhibition of casein kinase II.
    Ravi R, Bedi A.
    Cancer Res; 2002 Aug 01; 62(15):4180-5. PubMed ID: 12154014
    [Abstract] [Full Text] [Related]

  • 20. Involvement of c-FLIP and survivin down-regulation in flexible heteroarotinoid-induced apoptosis and enhancement of TRAIL-initiated apoptosis in lung cancer cells.
    Lin Y, Liu X, Yue P, Benbrook DM, Berlin KD, Khuri FR, Sun SY.
    Mol Cancer Ther; 2008 Nov 01; 7(11):3556-65. PubMed ID: 19001438
    [Abstract] [Full Text] [Related]

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