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204 related items for PubMed ID: 25533398

  • 1. Stability of single copy transgene expression in CHOK1 cells is affected by histone modifications but not by DNA methylation.
    Spencer S, Gugliotta A, Koenitzer J, Hauser H, Wirth D.
    J Biotechnol; 2015 Feb 10; 195():15-29. PubMed ID: 25533398
    [Abstract] [Full Text] [Related]

  • 2. Position effect variegation and epigenetic modification of a transgene in a pig model.
    Yin Z, Kong QR, Zhao ZP, Wu ML, Mu YS, Hu K, Liu ZH.
    Genet Mol Res; 2012 Feb 16; 11(1):355-69. PubMed ID: 22370938
    [Abstract] [Full Text] [Related]

  • 3. Promoter methylation and histone modifications affect the expression of the exogenous DsRed gene in transgenic goats.
    Nuo MT, Yuan JL, Yang WL, Gao XY, He N, Liang H, Cang M, Liu DJ.
    Genet Mol Res; 2016 Aug 29; 15(3):. PubMed ID: 27706651
    [Abstract] [Full Text] [Related]

  • 4. Mechanisms underlying epigenetic and transcriptional heterogeneity in Chinese hamster ovary (CHO) cell lines.
    Veith N, Ziehr H, MacLeod RA, Reamon-Buettner SM.
    BMC Biotechnol; 2016 Jan 22; 16():6. PubMed ID: 26800878
    [Abstract] [Full Text] [Related]

  • 5. Interplay of Promoter Usage and Intragenic CpG Content: Impact on GFP Reporter Gene Expression.
    Krinner S, Heitzer A, Asbach B, Wagner R.
    Hum Gene Ther; 2015 Dec 22; 26(12):826-40. PubMed ID: 26414116
    [Abstract] [Full Text] [Related]

  • 6. Silencing of fat-1 transgene expression in sheep may result from hypermethylation of its driven cytomegalovirus (CMV) promoter.
    Duan B, Cheng L, Gao Y, Yin FX, Su GH, Shen QY, Liu K, Hu X, Liu X, Li GP.
    Theriogenology; 2012 Sep 01; 78(4):793-802. PubMed ID: 22541322
    [Abstract] [Full Text] [Related]

  • 7. Epigenetic regulation of cytomegalovirus major immediate-early promoter activity in transgenic mice.
    Mehta AK, Majumdar SS, Alam P, Gulati N, Brahmachari V.
    Gene; 2009 Jan 01; 428(1-2):20-4. PubMed ID: 18976699
    [Abstract] [Full Text] [Related]

  • 8. Histone H3 acetylation and H3 K4 methylation define distinct chromatin regions permissive for transgene expression.
    Yan C, Boyd DD.
    Mol Cell Biol; 2006 Sep 01; 26(17):6357-71. PubMed ID: 16914722
    [Abstract] [Full Text] [Related]

  • 9. Epigenetic modulations rendering cell-to-cell variability and phenotypic metastability.
    Spencer S, Gugliotta A, Gödecke N, Hauser H, Wirth D.
    J Genet Genomics; 2016 Aug 20; 43(8):503-11. PubMed ID: 27569397
    [Abstract] [Full Text] [Related]

  • 10. Position effects are influenced by the orientation of a transgene with respect to flanking chromatin.
    Feng YQ, Lorincz MC, Fiering S, Greally JM, Bouhassira EE.
    Mol Cell Biol; 2001 Jan 20; 21(1):298-309. PubMed ID: 11113204
    [Abstract] [Full Text] [Related]

  • 11. Coordinated change of a ratio of methylated H3-lysine 4 or acetylated H3 to acetylated H4 and DNA methylation is associated with tissue-specific gene expression in cloned pig.
    Kang JK, Park KW, Chung YG, You JS, Kim YK, Lee SH, Hong SP, Choi KM, Heo KN, Seol JG, Lee JH, Jin DI, Park CS, Seo JS, Lee HW, Han JW.
    Exp Mol Med; 2007 Feb 28; 39(1):84-96. PubMed ID: 17334232
    [Abstract] [Full Text] [Related]

  • 12. Enhanced targeted DNA methylation of the CMV and endogenous promoters with dCas9-DNMT3A3L entails distinct subsequent histone modification changes in CHO cells.
    Marx N, Dhiman H, Schmieder V, Freire CM, Nguyen LN, Klanert G, Borth N.
    Metab Eng; 2021 Jul 28; 66():268-282. PubMed ID: 33965614
    [Abstract] [Full Text] [Related]

  • 13. High levels of histone H3 acetylation at the CMV promoter are predictive of stable expression in Chinese hamster ovary cells.
    Moritz B, Woltering L, Becker PB, Göpfert U.
    Biotechnol Prog; 2016 May 28; 32(3):776-86. PubMed ID: 27073121
    [Abstract] [Full Text] [Related]

  • 14. Insertion of core CpG island element into human CMV promoter for enhancing recombinant protein expression stability in CHO cells.
    Mariati, Yeo JH, Koh EY, Ho SC, Yang Y.
    Biotechnol Prog; 2014 May 28; 30(3):523-34. PubMed ID: 24789630
    [Abstract] [Full Text] [Related]

  • 15. DNA methylation and histone modifications are the molecular lock in lentivirally transduced hematopoietic progenitor cells.
    Ngai SC, Rosli R, Al Abbar A, Abdullah S.
    Biomed Res Int; 2015 May 28; 2015():346134. PubMed ID: 25961011
    [Abstract] [Full Text] [Related]

  • 16. Dynamic DNA methylation and histone modifications contribute to lentiviral transgene silencing in murine embryonic carcinoma cells.
    He J, Yang Q, Chang LJ.
    J Virol; 2005 Nov 28; 79(21):13497-508. PubMed ID: 16227270
    [Abstract] [Full Text] [Related]

  • 17. Promoter methylation and transgene copy numbers predict unstable protein production in recombinant Chinese hamster ovary cell lines.
    Osterlehner A, Simmeth S, Göpfert U.
    Biotechnol Bioeng; 2011 Nov 28; 108(11):2670-81. PubMed ID: 21618470
    [Abstract] [Full Text] [Related]

  • 18. Revealing Key Determinants of Clonal Variation in Transgene Expression in Recombinant CHO Cells Using Targeted Genome Editing.
    Lee JS, Park JH, Ha TK, Samoudi M, Lewis NE, Palsson BO, Kildegaard HF, Lee GM.
    ACS Synth Biol; 2018 Dec 21; 7(12):2867-2878. PubMed ID: 30388888
    [Abstract] [Full Text] [Related]

  • 19. Transgene-induced silencing of Arabidopsis phytochrome A gene via exonic methylation.
    Chawla R, Nicholson SJ, Folta KM, Srivastava V.
    Plant J; 2007 Dec 21; 52(6):1105-18. PubMed ID: 17931351
    [Abstract] [Full Text] [Related]

  • 20. Transcriptional silencing is associated with extensive methylation of the CMV promoter following adenoviral gene delivery to muscle.
    Brooks AR, Harkins RN, Wang P, Qian HS, Liu P, Rubanyi GM.
    J Gene Med; 2004 Apr 21; 6(4):395-404. PubMed ID: 15079814
    [Abstract] [Full Text] [Related]

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