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Journal Abstract Search

296 related items for PubMed ID: 25544754

  • 1. Dichloroacetate, a selective mitochondria-targeting drug for oral squamous cell carcinoma: a metabolic perspective of treatment.
    Ruggieri V, Agriesti F, Scrima R, Laurenzana I, Perrone D, Tataranni T, Mazzoccoli C, Lo Muzio L, Capitanio N, Piccoli C.
    Oncotarget; 2015 Jan 20; 6(2):1217-30. PubMed ID: 25544754
    [Abstract] [Full Text] [Related]

  • 2. Dichloroacetate Affects Mitochondrial Function and Stemness-Associated Properties in Pancreatic Cancer Cell Lines.
    Tataranni T, Agriesti F, Pacelli C, Ruggieri V, Laurenzana I, Mazzoccoli C, Sala GD, Panebianco C, Pazienza V, Capitanio N, Piccoli C.
    Cells; 2019 May 18; 8(5):. PubMed ID: 31109089
    [Abstract] [Full Text] [Related]

  • 3. Activation of mitochondrial oxidation by PDK2 inhibition reverses cisplatin resistance in head and neck cancer.
    Roh JL, Park JY, Kim EH, Jang HJ, Kwon M.
    Cancer Lett; 2016 Feb 01; 371(1):20-9. PubMed ID: 26607904
    [Abstract] [Full Text] [Related]

  • 4. The effect of dichloroacetate in canine prostate adenocarcinomas and transitional cell carcinomas in vitro.
    Harting T, Stubbendorff M, Willenbrock S, Wagner S, Schadzek P, Ngezahayo A, Murua Escobar HM, Nolte I.
    Int J Oncol; 2016 Dec 01; 49(6):2341-2350. PubMed ID: 27748833
    [Abstract] [Full Text] [Related]

  • 5. Sodium dichloroacetate selectively targets cells with defects in the mitochondrial ETC.
    Stockwin LH, Yu SX, Borgel S, Hancock C, Wolfe TL, Phillips LR, Hollingshead MG, Newton DL.
    Int J Cancer; 2010 Dec 01; 127(11):2510-9. PubMed ID: 20533281
    [Abstract] [Full Text] [Related]

  • 6. Inactivation of the HIF-1α/PDK3 signaling axis drives melanoma toward mitochondrial oxidative metabolism and potentiates the therapeutic activity of pro-oxidants.
    Kluza J, Corazao-Rozas P, Touil Y, Jendoubi M, Maire C, Guerreschi P, Jonneaux A, Ballot C, Balayssac S, Valable S, Corroyer-Dulmont A, Bernaudin M, Malet-Martino M, de Lassalle EM, Maboudou P, Formstecher P, Polakowska R, Mortier L, Marchetti P.
    Cancer Res; 2012 Oct 01; 72(19):5035-47. PubMed ID: 22865452
    [Abstract] [Full Text] [Related]

  • 7. Targeting of two aspects of metabolism in breast cancer treatment.
    Gang BP, Dilda PJ, Hogg PJ, Blackburn AC.
    Cancer Biol Ther; 2014 Oct 01; 15(11):1533-41. PubMed ID: 25482950
    [Abstract] [Full Text] [Related]

  • 8. Dual-targeting of aberrant glucose metabolism in glioblastoma.
    Shen H, Decollogne S, Dilda PJ, Hau E, Chung SA, Luk PP, Hogg PJ, McDonald KL.
    J Exp Clin Cancer Res; 2015 Feb 05; 34(1):14. PubMed ID: 25652202
    [Abstract] [Full Text] [Related]

  • 9. Multi-modality imaging to assess metabolic response to dichloroacetate treatment in tumor models.
    Neveu MA, De Preter G, Joudiou N, Bol A, Brender JR, Saito K, Kishimoto S, Grégoire V, Jordan BF, Krishna MC, Feron O, Gallez B.
    Oncotarget; 2016 Dec 06; 7(49):81741-81749. PubMed ID: 28082726
    [Abstract] [Full Text] [Related]

  • 10. Targeted reversal and phosphorescence lifetime imaging of cancer cell metabolism via a theranostic rhenium(I)-DCA conjugate.
    Yang J, Cao Q, Zhang H, Hao L, Zhou D, Gan Z, Li Z, Tong YX, Ji LN, Mao ZW.
    Biomaterials; 2018 Sep 06; 176():94-105. PubMed ID: 29870900
    [Abstract] [Full Text] [Related]

  • 11. Metabolic modulation of glioblastoma with dichloroacetate.
    Michelakis ED, Sutendra G, Dromparis P, Webster L, Haromy A, Niven E, Maguire C, Gammer TL, Mackey JR, Fulton D, Abdulkarim B, McMurtry MS, Petruk KC.
    Sci Transl Med; 2010 May 12; 2(31):31ra34. PubMed ID: 20463368
    [Abstract] [Full Text] [Related]

  • 12. Antitumor and chemosensitizing action of dichloroacetate implicates modulation of tumor microenvironment: a role of reorganized glucose metabolism, cell survival regulation and macrophage differentiation.
    Kumar A, Kant S, Singh SM.
    Toxicol Appl Pharmacol; 2013 Nov 15; 273(1):196-208. PubMed ID: 24051182
    [Abstract] [Full Text] [Related]

  • 13. Liquid Chromatography-Tandem Mass Spectrometry Method Revealed that Lung Cancer Cells Exhibited Distinct Metabolite Profiles upon the Treatment with Different Pyruvate Dehydrogenase Kinase Inhibitors.
    Zhang W, Hu X, Zhou W, Tam KY.
    J Proteome Res; 2018 Sep 07; 17(9):3012-3021. PubMed ID: 30028142
    [Abstract] [Full Text] [Related]

  • 14. Dichloroacetate and Pyruvate Metabolism: Pyruvate Dehydrogenase Kinases as Targets Worth Investigating for Effective Therapy of Toxoplasmosis.
    Ferrarini MG, Nisimura LM, Girard RMBM, Alencar MB, Fragoso MSI, Araújo-Silva CA, Veiga AA, Abud APR, Nardelli SC, Vommaro RC, Silber AM, France-Sagot M, Ávila AR.
    mSphere; 2021 Jan 06; 6(1):. PubMed ID: 33408226
    [Abstract] [Full Text] [Related]

  • 15. Dichloroacetate induces apoptosis in endometrial cancer cells.
    Wong JY, Huggins GS, Debidda M, Munshi NC, De Vivo I.
    Gynecol Oncol; 2008 Jun 06; 109(3):394-402. PubMed ID: 18423823
    [Abstract] [Full Text] [Related]

  • 16. Mito-DCA: a mitochondria targeted molecular scaffold for efficacious delivery of metabolic modulator dichloroacetate.
    Pathak RK, Marrache S, Harn DA, Dhar S.
    ACS Chem Biol; 2014 May 16; 9(5):1178-87. PubMed ID: 24617941
    [Abstract] [Full Text] [Related]

  • 17. The combined effect of dichloroacetate and 3-bromopyruvate on glucose metabolism in colorectal cancer cell line, HT-29; the mitochondrial pathway apoptosis.
    Nikravesh H, Khodayar MJ, Behmanesh B, Mahdavinia M, Teimoori A, Alboghobeish S, Zeidooni L.
    BMC Cancer; 2021 Aug 07; 21(1):903. PubMed ID: 34364387
    [Abstract] [Full Text] [Related]

  • 18. ITGB2-mediated metabolic switch in CAFs promotes OSCC proliferation by oxidation of NADH in mitochondrial oxidative phosphorylation system.
    Zhang X, Dong Y, Zhao M, Ding L, Yang X, Jing Y, Song Y, Chen S, Hu Q, Ni Y.
    Theranostics; 2020 Aug 07; 10(26):12044-12059. PubMed ID: 33204328
    [Abstract] [Full Text] [Related]

  • 19. Sensitization of metformin-cytotoxicity by dichloroacetate via reprogramming glucose metabolism in cancer cells.
    Choi YW, Lim IK.
    Cancer Lett; 2014 May 01; 346(2):300-8. PubMed ID: 24480191
    [Abstract] [Full Text] [Related]

  • 20. Therapeutic Targeting of the Pyruvate Dehydrogenase Complex/Pyruvate Dehydrogenase Kinase (PDC/PDK) Axis in Cancer.
    Stacpoole PW.
    J Natl Cancer Inst; 2017 Nov 01; 109(11):. PubMed ID: 29059435
    [Abstract] [Full Text] [Related]

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