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206 related items for PubMed ID: 25550199

  • 1. Cytokine-induced S-nitrosylation of soluble guanylyl cyclase and expression of phosphodiesterase 1A contribute to dysfunction of longitudinal smooth muscle relaxation.
    Rajagopal S, Nalli AD, Kumar DP, Bhattacharya S, Hu W, Mahavadi S, Grider JR, Murthy KS.
    J Pharmacol Exp Ther; 2015 Mar; 352(3):509-18. PubMed ID: 25550199
    [Abstract] [Full Text] [Related]

  • 2. Cytokine-induced iNOS and ERK1/2 inhibit adenylyl cyclase type 5/6 activity and stimulate phosphodiesterase 4D5 activity in intestinal longitudinal smooth muscle.
    Mahavadi S, Nalli AD, Kumar DP, Hu W, Kuemmerle JF, Grider JR, Murthy KS.
    Am J Physiol Cell Physiol; 2014 Aug 15; 307(4):C402-11. PubMed ID: 24944202
    [Abstract] [Full Text] [Related]

  • 3. Soluble guanylyl cyclase (sGC) degradation and impairment of nitric oxide-mediated responses in urethra from obese mice: reversal by the sGC activator BAY 60-2770.
    Alexandre EC, Leiria LO, Silva FH, Mendes-Silvério CB, Calmasini FB, Davel AP, Mónica FZ, De Nucci G, Antunes E.
    J Pharmacol Exp Ther; 2014 Apr 15; 349(1):2-9. PubMed ID: 24421320
    [Abstract] [Full Text] [Related]

  • 4. Mechanism of relaxation and interaction with nitric oxide of the soluble guanylate cyclase stimulator BAY 41-2272 in mouse gastric fundus and colon.
    Cosyns SM, Lefebvre RA.
    Eur J Pharmacol; 2012 Jul 05; 686(1-3):104-15. PubMed ID: 22575520
    [Abstract] [Full Text] [Related]

  • 5. Involvement of soluble guanylate cyclase alpha(1) and alpha(2), and SK(Ca) channels in NANC relaxation of mouse distal colon.
    Dhaese I, Vanneste G, Sips P, Buys E, Brouckaert P, Lefebvre RA.
    Eur J Pharmacol; 2008 Jul 28; 589(1-3):251-9. PubMed ID: 18572161
    [Abstract] [Full Text] [Related]

  • 6. Effects of 5-cyclopropyl-2-[1-(2-fluoro-benzyl)-1H-pyrazolo[3,4-b]pyridine-3-yl]pyrimidin-4-ylamine (BAY 41-2272) on smooth muscle tone, soluble guanylyl cyclase activity, and NADPH oxidase activity/expression in corpus cavernosum from wild-type, neuronal, and endothelial nitric-oxide synthase null mice.
    Teixeira CE, Priviero FB, Webb RC.
    J Pharmacol Exp Ther; 2007 Sep 28; 322(3):1093-102. PubMed ID: 17596536
    [Abstract] [Full Text] [Related]

  • 7. Inhibitory phosphorylation of soluble guanylyl cyclase by muscarinic m2 receptors via Gbetagamma-dependent activation of c-Src kinase.
    Murthy KS.
    J Pharmacol Exp Ther; 2008 Apr 28; 325(1):183-9. PubMed ID: 18180373
    [Abstract] [Full Text] [Related]

  • 8. Multiple mechanisms of vascular smooth muscle relaxation by the activation of proteinase-activated receptor 2 in mouse mesenteric arterioles.
    McGuire JJ, Hollenberg MD, Andrade-Gordon P, Triggle CR.
    Br J Pharmacol; 2002 Jan 28; 135(1):155-69. PubMed ID: 11786491
    [Abstract] [Full Text] [Related]

  • 9. Pharmacological characterisation of the relaxation induced by the soluble guanylate cyclase activator, BAY 60-2770 in rabbit corpus cavernosum.
    Estancial CS, Rodrigues RL, De Nucci G, Antunes E, Mónica FZ.
    BJU Int; 2015 Oct 28; 116(4):657-64. PubMed ID: 25715977
    [Abstract] [Full Text] [Related]

  • 10. Mechanisms of relaxant activity of the nitric oxide-independent soluble guanylyl cyclase stimulator BAY 41-2272 in rat tracheal smooth muscle.
    Toque HA, Mónica FZ, Morganti RP, De Nucci G, Antunes E.
    Eur J Pharmacol; 2010 Oct 25; 645(1-3):158-64. PubMed ID: 20670622
    [Abstract] [Full Text] [Related]

  • 11. Inhibition of proinflammatory tumor necrosis factor-{alpha}-induced inducible nitric-oxide synthase by xanthine-based 7-[2-[4-(2-chlorobenzene)piperazinyl]ethyl]-1,3-dimethylxanthine (KMUP-1) and 7-[2-[4-(4-nitrobenzene)piperazinyl]ethyl]-1, 3-dimethylxanthine (KMUP-3) in rat trachea: The involvement of soluble guanylate cyclase and protein kinase G.
    Wu BN, Chen CW, Liou SF, Yeh JL, Chung HH, Chen IJ.
    Mol Pharmacol; 2006 Sep 25; 70(3):977-85. PubMed ID: 16754782
    [Abstract] [Full Text] [Related]

  • 12. Evaluation of the relaxant effect of the nitric oxide-independent soluble guanylyl cyclase stimulator BAY 41-2272 in isolated detrusor smooth muscle.
    Báu FR, Mónica FZ, Priviero FB, Baldissera L, de Nucci G, Antunes E.
    Eur J Pharmacol; 2010 Jul 10; 637(1-3):171-7. PubMed ID: 20399768
    [Abstract] [Full Text] [Related]

  • 13. Desensitization of the soluble guanylyl cyclase/cGMP pathway by lipopolysaccharide in rat isolated pulmonary artery but not aorta.
    El-Awady MS, Smirnov SV, Watson ML.
    Br J Pharmacol; 2008 Dec 10; 155(8):1164-73. PubMed ID: 18806822
    [Abstract] [Full Text] [Related]

  • 14. Acrylamide analog as a novel nitric oxide-independent soluble guanylyl cyclase activator.
    Nakane M, Kolasa T, Chang R, Miller LN, Moreland RB, Brioni JD.
    J Pharmacol Sci; 2006 Oct 10; 102(2):231-8. PubMed ID: 17050951
    [Abstract] [Full Text] [Related]

  • 15. KMUP-1, a xanthine derivative, induces relaxation of guinea-pig isolated trachea: the role of the epithelium, cyclic nucleotides and K+ channels.
    Wu BN, Lin RJ, Lo YC, Shen KP, Wang CC, Lin YT, Chen IJ.
    Br J Pharmacol; 2004 Aug 10; 142(7):1105-14. PubMed ID: 15237094
    [Abstract] [Full Text] [Related]

  • 16. The role of regulatory proteins and S-nitrosylation of endothelial nitric oxide synthase in the human clitoris: implications for female sexual function.
    Oliver JL, Kavoussi PK, Smith RP, Woodson RI, Corbett ST, Costabile RA, Palmer LA, Lysiak JJ.
    J Sex Med; 2014 Aug 10; 11(8):1927-35. PubMed ID: 24836757
    [Abstract] [Full Text] [Related]

  • 17. The relaxation induced by uroguanylin and the expression of natriuretic peptide receptors in human corpora cavernosa.
    Sousa CM, Havt A, Santos CF, Arnaud-Batista FJ, Cunha KM, Cerqueira JB, Fonteles MC, Nascimento NR.
    J Sex Med; 2010 Nov 10; 7(11):3610-9. PubMed ID: 20102442
    [Abstract] [Full Text] [Related]

  • 18. Regulation of Sertoli cell tight junction dynamics in the rat testis via the nitric oxide synthase/soluble guanylate cyclase/3',5'-cyclic guanosine monophosphate/protein kinase G signaling pathway: an in vitro study.
    Lee NP, Cheng CY.
    Endocrinology; 2003 Jul 10; 144(7):3114-29. PubMed ID: 12810568
    [Abstract] [Full Text] [Related]

  • 19. Functional role of the soluble guanylyl cyclase alpha(1) subunit in vascular smooth muscle relaxation.
    Nimmegeers S, Sips P, Buys E, Brouckaert P, Van de Voorde J.
    Cardiovasc Res; 2007 Oct 01; 76(1):149-59. PubMed ID: 17610859
    [Abstract] [Full Text] [Related]

  • 20. The soluble guanylate cyclase stimulator riociguat and the soluble guanylate cyclase activator cinaciguat exert no direct effects on contractility and relaxation of cardiac myocytes from normal rats.
    Reinke Y, Gross S, Eckerle LG, Hertrich I, Busch M, Busch R, Riad A, Rauch BH, Stasch JP, Dörr M, Felix SB.
    Eur J Pharmacol; 2015 Nov 15; 767():1-9. PubMed ID: 26407652
    [Abstract] [Full Text] [Related]


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