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Journal Abstract Search

693 related items for PubMed ID: 25554016

  • 1. Quinazoline based small molecule exerts potent tumour suppressive properties by inhibiting PI3K/Akt/FoxO3a signalling in experimental colon cancer.
    Qazi AK, Hussain A, Khan S, Aga MA, Behl A, Ali S, Singh SK, Taneja SC, Shah BA, Saxena AK, Mondhe DM, Hamid A.
    Cancer Lett; 2015 Apr 01; 359(1):47-56. PubMed ID: 25554016
    [Abstract] [Full Text] [Related]

  • 2. The inhibition of activated hepatic stellate cells proliferation by arctigenin through G0/G1 phase cell cycle arrest: persistent p27(Kip1) induction by interfering with PI3K/Akt/FOXO3a signaling pathway.
    Li A, Wang J, Wu M, Zhang X, Zhang H.
    Eur J Pharmacol; 2015 Jan 15; 747():71-87. PubMed ID: 25498792
    [Abstract] [Full Text] [Related]

  • 3. PDK1 is a potential therapeutic target against angiosarcoma cells.
    Wada M, Horinaka M, Yasuda S, Masuzawa M, Sakai T, Katoh N.
    J Dermatol Sci; 2015 Apr 15; 78(1):44-50. PubMed ID: 25726712
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  • 4. Amiloride sensitizes human pancreatic cancer cells to erlotinib in vitro through inhibition of the PI3K/AKT signaling pathway.
    Zheng YT, Yang HY, Li T, Zhao B, Shao TF, Xiang XQ, Cai WM.
    Acta Pharmacol Sin; 2015 May 15; 36(5):614-26. PubMed ID: 25864651
    [Abstract] [Full Text] [Related]

  • 5. Methylseleninic acid promotes antitumour effects via nuclear FOXO3a translocation through Akt inhibition.
    Tarrado-Castellarnau M, Cortés R, Zanuy M, Tarragó-Celada J, Polat IH, Hill R, Fan TW, Link W, Cascante M.
    Pharmacol Res; 2015 Dec 15; 102():218-34. PubMed ID: 26375988
    [Abstract] [Full Text] [Related]

  • 6. Tankyrase Inhibition Blocks Wnt/β-Catenin Pathway and Reverts Resistance to PI3K and AKT Inhibitors in the Treatment of Colorectal Cancer.
    Arqués O, Chicote I, Puig I, Tenbaum SP, Argilés G, Dienstmann R, Fernández N, Caratù G, Matito J, Silberschmidt D, Rodon J, Landolfi S, Prat A, Espín E, Charco R, Nuciforo P, Vivancos A, Shao W, Tabernero J, Palmer HG.
    Clin Cancer Res; 2016 Feb 01; 22(3):644-56. PubMed ID: 26224873
    [Abstract] [Full Text] [Related]

  • 7. FOXO3a reactivation mediates the synergistic cytotoxic effects of rapamycin and cisplatin in oral squamous cell carcinoma cells.
    Fang L, Wang H, Zhou L, Yu D.
    Toxicol Appl Pharmacol; 2011 Feb 15; 251(1):8-15. PubMed ID: 21092744
    [Abstract] [Full Text] [Related]

  • 8. Forkhead Box Transcription Factor (FOXO3a) mediates the cytotoxic effect of vernodalin in vitro and inhibits the breast tumor growth in vivo.
    Ananda Sadagopan SK, Mohebali N, Looi CY, Hasanpourghadi M, Pandurangan AK, Arya A, Karimian H, Mustafa MR.
    J Exp Clin Cancer Res; 2015 Dec 08; 34():147. PubMed ID: 26643256
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  • 12. Synergism of PI3K/Akt inhibition and Fas activation on colon cancer cell death.
    Zhu L, Derijard B, Chakrabandhu K, Wang BS, Chen HZ, Hueber AO.
    Cancer Lett; 2014 Nov 28; 354(2):355-64. PubMed ID: 25199763
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  • 13. Antitumor activity of pimasertib, a selective MEK 1/2 inhibitor, in combination with PI3K/mTOR inhibitors or with multi-targeted kinase inhibitors in pimasertib-resistant human lung and colorectal cancer cells.
    Martinelli E, Troiani T, D'Aiuto E, Morgillo F, Vitagliano D, Capasso A, Costantino S, Ciuffreda LP, Merolla F, Vecchione L, De Vriendt V, Tejpar S, Nappi A, Sforza V, Martini G, Berrino L, De Palma R, Ciardiello F.
    Int J Cancer; 2013 Nov 28; 133(9):2089-101. PubMed ID: 23629727
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  • 14. Targeting the Janus-activated kinase-2-STAT3 signalling pathway in pancreatic cancer using the HSP90 inhibitor ganetespib.
    Nagaraju GP, Mezina A, Shaib WL, Landry J, El-Rayes BF.
    Eur J Cancer; 2016 Jan 28; 52():109-19. PubMed ID: 26682870
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  • 15. Pazopanib, a novel multi-kinase inhibitor, shows potent antitumor activity in colon cancer through PUMA-mediated apoptosis.
    Zhang L, Wang H, Li W, Zhong J, Yu R, Huang X, Wang H, Tan Z, Wang J, Zhang Y.
    Oncotarget; 2017 Jan 10; 8(2):3289-3303. PubMed ID: 27924057
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  • 16. Marine lipopeptide Iturin A inhibits Akt mediated GSK3β and FoxO3a signaling and triggers apoptosis in breast cancer.
    Dey G, Bharti R, Dhanarajan G, Das S, Dey KK, Kumar BN, Sen R, Mandal M.
    Sci Rep; 2015 May 14; 5():10316. PubMed ID: 25974307
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  • 18. Down-regulation of Rictor enhances cell sensitivity to PI3K inhibitor LY294002 by blocking mTORC2-medicated phosphorylation of Akt/PRAS40 in esophageal squamous cell carcinoma.
    Hou G, Zhao Q, Zhang M, Fan T, Liu M, Shi X, Ren Y, Wang Y, Zhou J, Lu Z.
    Biomed Pharmacother; 2018 Oct 14; 106():1348-1356. PubMed ID: 30119206
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  • 20. FOXO3a mediates the cytotoxic effects of cisplatin in lung cancer cells.
    Liu H, Yin J, Wang C, Gu Y, Deng M, He Z.
    Anticancer Drugs; 2014 Sep 14; 25(8):898-907. PubMed ID: 24814195
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