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377 related items for PubMed ID: 25554447

  • 1. Aberrant zinc binding to immature conformers of metal-free copper-zinc superoxide dismutase triggers amorphous aggregation.
    Leal SS, Cristóvão JS, Biesemeier A, Cardoso I, Gomes CM.
    Metallomics; 2015 Feb; 7(2):333-46. PubMed ID: 25554447
    [Abstract] [Full Text] [Related]

  • 2. Curcumin binds to the pre-fibrillar aggregates of Cu/Zn superoxide dismutase (SOD1) and alters its amyloidogenic pathway resulting in reduced cytotoxicity.
    Bhatia NK, Srivastava A, Katyal N, Jain N, Khan MA, Kundu B, Deep S.
    Biochim Biophys Acta; 2015 May; 1854(5):426-36. PubMed ID: 25666897
    [Abstract] [Full Text] [Related]

  • 3. The Disulfide Bond, but Not Zinc or Dimerization, Controls Initiation and Seeded Growth in Amyotrophic Lateral Sclerosis-linked Cu,Zn Superoxide Dismutase (SOD1) Fibrillation.
    Chattopadhyay M, Nwadibia E, Strong CD, Gralla EB, Valentine JS, Whitelegge JP.
    J Biol Chem; 2015 Dec 18; 290(51):30624-36. PubMed ID: 26511321
    [Abstract] [Full Text] [Related]

  • 4. Cupric ions induce the oxidation and trigger the aggregation of human superoxide dismutase 1.
    Li C, Xu WC, Xie ZS, Pan K, Hu J, Chen J, Pang DW, Yang FQ, Liang Y.
    PLoS One; 2013 Dec 18; 8(6):e65287. PubMed ID: 23755211
    [Abstract] [Full Text] [Related]

  • 5. The Role of Metal Binding in the Amyotrophic Lateral Sclerosis-Related Aggregation of Copper-Zinc Superoxide Dismutase.
    Sirangelo I, Iannuzzi C.
    Molecules; 2017 Aug 29; 22(9):. PubMed ID: 28850080
    [Abstract] [Full Text] [Related]

  • 6. Calcium ions promote superoxide dismutase 1 (SOD1) aggregation into non-fibrillar amyloid: a link to toxic effects of calcium overload in amyotrophic lateral sclerosis (ALS)?
    Leal SS, Cardoso I, Valentine JS, Gomes CM.
    J Biol Chem; 2013 Aug 30; 288(35):25219-25228. PubMed ID: 23861388
    [Abstract] [Full Text] [Related]

  • 7. The metal cofactor zinc and interacting membranes modulate SOD1 conformation-aggregation landscape in an in vitro ALS model.
    Sannigrahi A, Chowdhury S, Das B, Banerjee A, Halder A, Kumar A, Saleem M, Naganathan AN, Karmakar S, Chattopadhyay K.
    Elife; 2021 Apr 07; 10():. PubMed ID: 33825682
    [Abstract] [Full Text] [Related]

  • 8. Mutant SOD1 instability: implications for toxicity in amyotrophic lateral sclerosis.
    Tiwari A, Hayward LJ.
    Neurodegener Dis; 2005 Apr 07; 2(3-4):115-27. PubMed ID: 16909016
    [Abstract] [Full Text] [Related]

  • 9. Early steps in oxidation-induced SOD1 misfolding: implications for non-amyloid protein aggregation in familial ALS.
    Mulligan VK, Kerman A, Laister RC, Sharda PR, Arslan PE, Chakrabartty A.
    J Mol Biol; 2012 Aug 24; 421(4-5):631-52. PubMed ID: 22542526
    [Abstract] [Full Text] [Related]

  • 10. Thermal fluctuations of immature SOD1 lead to separate folding and misfolding pathways.
    Sekhar A, Rumfeldt JA, Broom HR, Doyle CM, Bouvignies G, Meiering EM, Kay LE.
    Elife; 2015 Jun 23; 4():e07296. PubMed ID: 26099300
    [Abstract] [Full Text] [Related]

  • 11. Conformational Disorder of the Most Immature Cu, Zn-Superoxide Dismutase Leading to Amyotrophic Lateral Sclerosis.
    Furukawa Y, Anzai I, Akiyama S, Imai M, Cruz FJ, Saio T, Nagasawa K, Nomura T, Ishimori K.
    J Biol Chem; 2016 Feb 19; 291(8):4144-55. PubMed ID: 26694608
    [Abstract] [Full Text] [Related]

  • 12. Mechanical probes of SOD1 predict systematic trends in metal and dimer affinity of ALS-associated mutants.
    Das A, Plotkin SS.
    J Mol Biol; 2013 Mar 11; 425(5):850-74. PubMed ID: 23291526
    [Abstract] [Full Text] [Related]

  • 13. Disulfide-reduced ALS variants of Cu, Zn superoxide dismutase exhibit increased populations of unfolded species.
    Kayatekin C, Zitzewitz JA, Matthews CR.
    J Mol Biol; 2010 Apr 30; 398(2):320-31. PubMed ID: 20184893
    [Abstract] [Full Text] [Related]

  • 14. Molecular dynamics using atomic-resolution structure reveal structural fluctuations that may lead to polymerization of human Cu-Zn superoxide dismutase.
    Strange RW, Yong CW, Smith W, Hasnain SS.
    Proc Natl Acad Sci U S A; 2007 Jun 12; 104(24):10040-4. PubMed ID: 17548825
    [Abstract] [Full Text] [Related]

  • 15. Voltage-Induced Misfolding of Zinc-Replete ALS Mutant Superoxide Dismutase-1.
    Shi Y, Acerson MJ, Shuford KL, Shaw BF.
    ACS Chem Neurosci; 2015 Oct 21; 6(10):1696-707. PubMed ID: 26207449
    [Abstract] [Full Text] [Related]

  • 16. Denaturational stress induces formation of zinc-deficient monomers of Cu,Zn superoxide dismutase: implications for pathogenesis in amyotrophic lateral sclerosis.
    Mulligan VK, Kerman A, Ho S, Chakrabartty A.
    J Mol Biol; 2008 Nov 07; 383(2):424-36. PubMed ID: 18761352
    [Abstract] [Full Text] [Related]

  • 17. Effects of maturation on the conformational free-energy landscape of SOD1.
    Culik RM, Sekhar A, Nagesh J, Deol H, Rumfeldt JAO, Meiering EM, Kay LE.
    Proc Natl Acad Sci U S A; 2018 Mar 13; 115(11):E2546-E2555. PubMed ID: 29483249
    [Abstract] [Full Text] [Related]

  • 18. Variable metallation of human superoxide dismutase: atomic resolution crystal structures of Cu-Zn, Zn-Zn and as-isolated wild-type enzymes.
    Strange RW, Antonyuk SV, Hough MA, Doucette PA, Valentine JS, Hasnain SS.
    J Mol Biol; 2006 Mar 10; 356(5):1152-62. PubMed ID: 16406071
    [Abstract] [Full Text] [Related]

  • 19. Disruption of mitochondrial membrane integrity induced by amyloid aggregates arising from variants of SOD1.
    Oladzad Abbasabadi A, Javanian A, Nikkhah M, Meratan AA, Ghiasi P, Nemat-Gorgani M.
    Int J Biol Macromol; 2013 Oct 10; 61():212-7. PubMed ID: 23872456
    [Abstract] [Full Text] [Related]

  • 20. Effect of metal loading and subcellular pH on net charge of superoxide dismutase-1.
    Shi Y, Mowery RA, Shaw BF.
    J Mol Biol; 2013 Nov 15; 425(22):4388-404. PubMed ID: 23871896
    [Abstract] [Full Text] [Related]

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