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Journal Abstract Search

422 related items for PubMed ID: 25561469

  • 1. Characterization of human cyclin-dependent kinase 12 (CDK12) and CDK13 complexes in C-terminal domain phosphorylation, gene transcription, and RNA processing.
    Liang K, Gao X, Gilmore JM, Florens L, Washburn MP, Smith E, Shilatifard A.
    Mol Cell Biol; 2015 Mar; 35(6):928-38. PubMed ID: 25561469
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  • 2. CDK12 is a transcription elongation-associated CTD kinase, the metazoan ortholog of yeast Ctk1.
    Bartkowiak B, Liu P, Phatnani HP, Fuda NJ, Cooper JJ, Price DH, Adelman K, Lis JT, Greenleaf AL.
    Genes Dev; 2010 Oct 15; 24(20):2303-16. PubMed ID: 20952539
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  • 6. Interaction of cyclin-dependent kinase 12/CrkRS with cyclin K1 is required for the phosphorylation of the C-terminal domain of RNA polymerase II.
    Cheng SW, Kuzyk MA, Moradian A, Ichu TA, Chang VC, Tien JF, Vollett SE, Griffith M, Marra MA, Morin GB.
    Mol Cell Biol; 2012 Nov 15; 32(22):4691-704. PubMed ID: 22988298
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  • 7. Cdk12 and Cdk13 regulate axonal elongation through a common signaling pathway that modulates Cdk5 expression.
    Chen HR, Lin GT, Huang CK, Fann MJ.
    Exp Neurol; 2014 Nov 15; 261():10-21. PubMed ID: 24999027
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  • 8. Covalent targeting of remote cysteine residues to develop CDK12 and CDK13 inhibitors.
    Zhang T, Kwiatkowski N, Olson CM, Dixon-Clarke SE, Abraham BJ, Greifenberg AK, Ficarro SB, Elkins JM, Liang Y, Hannett NM, Manz T, Hao M, Bartkowiak B, Greenleaf AL, Marto JA, Geyer M, Bullock AN, Young RA, Gray NS.
    Nat Chem Biol; 2016 Oct 15; 12(10):876-84. PubMed ID: 27571479
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  • 9. CDK12 globally stimulates RNA polymerase II transcription elongation and carboxyl-terminal domain phosphorylation.
    Tellier M, Zaborowska J, Caizzi L, Mohammad E, Velychko T, Schwalb B, Ferrer-Vicens I, Blears D, Nojima T, Cramer P, Murphy S.
    Nucleic Acids Res; 2020 Aug 20; 48(14):7712-7727. PubMed ID: 32805052
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  • 14. Expression, purification, and identification of associated proteins of the full-length hCDK12/CyclinK complex.
    Bartkowiak B, Greenleaf AL.
    J Biol Chem; 2015 Jan 16; 290(3):1786-95. PubMed ID: 25429106
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