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Journal Abstract Search

170 related items for PubMed ID: 25593987

  • 1. Novel LIMK2 Inhibitor Blocks Panc-1 Tumor Growth in a mouse xenograft model.
    Rak R, Haklai R, Elad-Tzfadia G, Wolfson HJ, Carmeli S, Kloog Y.
    Oncoscience; 2014; 1(1):39-48. PubMed ID: 25593987
    [Abstract] [Full Text] [Related]

  • 2. Computer-based identification of a novel LIMK1/2 inhibitor that synergizes with salirasib to destabilize the actin cytoskeleton.
    Mashiach-Farkash E, Rak R, Elad-Sfadia G, Haklai R, Carmeli S, Kloog Y, Wolfson HJ.
    Oncotarget; 2012 Jun; 3(6):629-39. PubMed ID: 22776759
    [Abstract] [Full Text] [Related]

  • 3. LIMK/cofilin pathway and Slingshot are implicated in human colorectal cancer progression and chemoresistance.
    Aggelou H, Chadla P, Nikou S, Karteri S, Maroulis I, Kalofonos HP, Papadaki H, Bravou V.
    Virchows Arch; 2018 May; 472(5):727-737. PubMed ID: 29352327
    [Abstract] [Full Text] [Related]

  • 4. LIMK1 and LIMK2 are important for metastatic behavior and tumor cell-induced angiogenesis of pancreatic cancer cells.
    Vlecken DH, Bagowski CP.
    Zebrafish; 2009 Dec; 6(4):433-9. PubMed ID: 20047470
    [Abstract] [Full Text] [Related]

  • 5. LIMK1/2 inhibitor LIMKi 3 suppresses porcine oocyte maturation.
    Jia RX, Duan X, Song SJ, Sun SC.
    PeerJ; 2016 Dec; 4():e2553. PubMed ID: 27761340
    [Abstract] [Full Text] [Related]

  • 6. LIMK2-1, a new isoform of human LIMK2, regulates actin cytoskeleton remodeling via a different signaling pathway than that of its two homologs, LIMK2a and LIMK2b.
    Vallée B, Cuberos H, Doudeau M, Godin F, Gosset D, Vourc'h P, Andres CR, Bénédetti H.
    Biochem J; 2018 Dec 06; 475(23):3745-3761. PubMed ID: 30373762
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  • 8. Lim kinases, regulators of actin dynamics.
    Bernard O.
    Int J Biochem Cell Biol; 2007 Dec 06; 39(6):1071-6. PubMed ID: 17188549
    [Abstract] [Full Text] [Related]

  • 9. LIM kinase inhibitor T56-LIMKi protects mouse brain from photothrombotic stroke.
    Demyanenko SV, Uzdensky A.
    Brain Inj; 2021 Mar 21; 35(4):490-500. PubMed ID: 33523710
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  • 11. Tetrahydropyridine LIMK inhibitors: Structure activity studies and biological characterization.
    Champiré A, Berabez R, Braka A, Cosson A, Corret J, Girardin C, Serrano A, Aci-Sèche S, Bonnet P, Josselin B, Brindeau P, Ruchaud S, Leguevel R, Chatterjee D, Mathea S, Knapp S, Brion R, Verrecchia F, Vallée B, Plé K, Bénédetti H, Routier S.
    Eur J Med Chem; 2024 May 05; 271():116391. PubMed ID: 38669909
    [Abstract] [Full Text] [Related]

  • 12. Deletion of Limk1 and Limk2 in mice does not alter cochlear development or auditory function.
    Fang Q, Zhang Y, Da P, Shao B, Pan H, He Z, Cheng C, Li D, Guo J, Wu X, Guan M, Liao M, Zhang Y, Sha S, Zhou Z, Wang J, Wang T, Su K, Chai R, Chen F.
    Sci Rep; 2019 Mar 04; 9(1):3357. PubMed ID: 30833597
    [Abstract] [Full Text] [Related]

  • 13. LIM kinase inhibitors disrupt mitotic microtubule organization and impair tumor cell proliferation.
    Mardilovich K, Baugh M, Crighton D, Kowalczyk D, Gabrielsen M, Munro J, Croft DR, Lourenco F, James D, Kalna G, McGarry L, Rath O, Shanks E, Garnett MJ, McDermott U, Brookfield J, Charles M, Hammonds T, Olson MF.
    Oncotarget; 2015 Nov 17; 6(36):38469-86. PubMed ID: 26540348
    [Abstract] [Full Text] [Related]

  • 14. Cofilin phosphorylation and actin cytoskeletal dynamics regulated by rho- and Cdc42-activated LIM-kinase 2.
    Sumi T, Matsumoto K, Takai Y, Nakamura T.
    J Cell Biol; 1999 Dec 27; 147(7):1519-32. PubMed ID: 10613909
    [Abstract] [Full Text] [Related]

  • 15. Preclinical Evaluation of a Novel Small Molecule Inhibitor of LIM Kinases (LIMK) CEL_Amide in Philadelphia-Chromosome Positive (BCR::ABL+) Acute Lymphoblastic Leukemia (ALL).
    Berrou J, Dupont M, Djamai H, Adicéam E, Parietti V, Kaci A, Clappier E, Cayuela JM, Baruchel A, Paublant F, Prudent R, Ghysdael J, Gardin C, Dombret H, Braun T.
    J Clin Med; 2022 Nov 15; 11(22):. PubMed ID: 36431240
    [Abstract] [Full Text] [Related]

  • 16. Structural Aspects of LIMK Regulation and Pharmacology.
    Chatterjee D, Preuss F, Dederer V, Knapp S, Mathea S.
    Cells; 2022 Jan 02; 11(1):. PubMed ID: 35011704
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  • 19. LIM-kinase 2 induces formation of stress fibres, focal adhesions and membrane blebs, dependent on its activation by Rho-associated kinase-catalysed phosphorylation at threonine-505.
    Amano T, Tanabe K, Eto T, Narumiya S, Mizuno K.
    Biochem J; 2001 Feb 15; 354(Pt 1):149-59. PubMed ID: 11171090
    [Abstract] [Full Text] [Related]

  • 20. LIM kinases are attractive targets with many macromolecular partners and only a few small molecule regulators.
    Manetti F.
    Med Res Rev; 2012 Sep 15; 32(5):968-98. PubMed ID: 22886629
    [Abstract] [Full Text] [Related]

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