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Journal Abstract Search


127 related items for PubMed ID: 2559492

  • 1. Pharmacology of a potent, new antithrombotic agent, 1,3-dihydro-7,8-dimethyl-2H-imidazo[4,5-b]quinolin-2-one (BMY-20844).
    Buchanan JO, Fleming JS, Cornish BT, Baryla UM, Gillespie E, Stanton HC, Seiler SM, Keely SL.
    Thromb Res; 1989 Nov 01; 56(3):333-46. PubMed ID: 2559492
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  • 2. 1,3-Dihydro-2H-imidazo[4,5-b]quinolin-2-ones--inhibitors of blood platelet cAMP phosphodiesterase and induced aggregation.
    Meanwell NA, Roth HR, Smith EC, Wedding DL, Wright JJ, Fleming JS, Gillespie E.
    J Med Chem; 1991 Sep 01; 34(9):2906-16. PubMed ID: 1654430
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  • 3. Inhibitors of blood platelet cAMP phosphodiesterase. 2. Structure-activity relationships associated with 1,3-dihydro-2H-imidazo[4,5-b]quinolin-2-ones substituted with functionalized side chains.
    Meanwell NA, Pearce BC, Roth HR, Smith EC, Wedding DL, Wright JJ, Buchanan JO, Baryla UM, Gamberdella M, Gillespie E.
    J Med Chem; 1992 Jul 10; 35(14):2672-87. PubMed ID: 1321910
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  • 6. 7-Bromo-1,5-dihydro-3,6-dimethylimidazo[2,1-b]quinazolin-2(3H)- one (Ro 15-2041), a potent antithrombotic agent that selectively inhibits platelet cyclic AMP-phosphodiesterase.
    Muggli R, Tschopp TB, Mittelholzer E, Baumgartner HR.
    J Pharmacol Exp Ther; 1985 Oct 10; 235(1):212-9. PubMed ID: 2995647
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  • 8. Antithrombotic effects of BMY21190, an inhibitor of cAMP phosphodiesterase, in a canine model of coronary artery thrombosis.
    Minami M, Driscoll EM, Lucchesi BR.
    Jpn Circ J; 1993 Oct 10; 57(10):979-92. PubMed ID: 8230679
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  • 11. Inhibitors of blood platelet cAMP phosphodiesterase. 4. Structural variation of the side-chain terminus of water-soluble 1,3-dihydro-2H-imidazo[4,5-b]quinolin-2-one derivatives.
    Meanwell NA, Hewawasam P, Thomas JA, Wright JJ, Russell JW, Gamberdella M, Goldenberg HJ, Seiler SM, Zavoico GB.
    J Med Chem; 1993 Oct 29; 36(22):3251-64. PubMed ID: 8230115
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  • 12. A potent and selective inhibitor of cyclic AMP phosphodiesterase with potential cardiotonic and antithrombotic properties.
    Alvarez R, Banerjee GL, Bruno JJ, Jones GL, Littschwager K, Strosberg AM, Venuti MC.
    Mol Pharmacol; 1986 Jun 29; 29(6):554-60. PubMed ID: 3012320
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  • 13. 2-[3-[2-(4,5-diphenyl-2-oxazolyl) ethyl] phenoxy] acetic acid (BMY 42393): 2). Oral activity and efficacy in animal models of arterial thrombosis.
    Seiler SM, Buchanan JO, Schumacher WA, Zavoico GB, Gamberdella M, Fleming JS, Meanwell NA.
    Thromb Res; 1994 Apr 15; 74(2):125-33. PubMed ID: 8029813
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  • 16. Antagonism of the GPIIb/IIIa receptor with the nonpeptidic molecule BIBU52: inhibition of platelet aggregation in vitro and antithrombotic efficacy in vivo.
    Guth BD, Seewaldt-Becker E, Himmelsbach F, Weisenberger H, Müller TH.
    J Cardiovasc Pharmacol; 1997 Aug 15; 30(2):261-72. PubMed ID: 9269956
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  • 17. Antithrombotic effects of KP-10614, a novel and stable prostacyclin (PGI2) analog.
    Kanayama T, Kimura Y, Iseki K, Hayashi Y, Tamao Y, Mizogami S.
    J Pharmacol Exp Ther; 1990 Dec 15; 255(3):1210-7. PubMed ID: 1702154
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  • 18. The antiaggregating and antithrombotic activity of clopidogrel is potentiated by aspirin in several experimental models in the rabbit.
    Herbert JM, Dol F, Bernat A, Falotico R, Lalé A, Savi P.
    Thromb Haemost; 1998 Sep 15; 80(3):512-8. PubMed ID: 9759636
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  • 19. 3,4-Dihydroquinolin-2(1H)-ones as combined inhibitors of thromboxane A2 synthase and cAMP phosphodiesterase.
    Martinez GR, Walker KA, Hirschfeld DR, Bruno JJ, Yang DS, Maloney PJ.
    J Med Chem; 1992 Feb 21; 35(4):620-8. PubMed ID: 1311763
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  • 20. Effect of vintoperol on platelet aggregation and experimental thrombosis.
    Csomor K, Kárpáti E.
    Arzneimittelforschung; 1994 Jan 21; 44(1):36-40. PubMed ID: 8135876
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