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227 related items for PubMed ID: 2559790

  • 1. Effect of the superoxide dismutase inhibitor, diethyldithiocarbamate, on the cytotoxicity of mitomycin antibiotics.
    Pritsos CA, Keyes SR, Sartorelli AC.
    Cancer Biochem Biophys; 1989 Oct; 10(4):289-98. PubMed ID: 2559790
    [Abstract] [Full Text] [Related]

  • 2. Generation of reactive oxygen radicals through bioactivation of mitomycin antibiotics.
    Pritsos CA, Sartorelli AC.
    Cancer Res; 1986 Jul; 46(7):3528-32. PubMed ID: 3011250
    [Abstract] [Full Text] [Related]

  • 3. Cytotoxicity and DNA lesions produced by mitomycin C and porfiromycin in hypoxic and aerobic EMT6 and Chinese hamster ovary cells.
    Fracasso PM, Sartorelli AC.
    Cancer Res; 1986 Aug; 46(8):3939-44. PubMed ID: 3089583
    [Abstract] [Full Text] [Related]

  • 4. Modification of the metabolism and cytotoxicity of bioreductive alkylating agents by dicoumarol in aerobic and hypoxic murine tumor cells.
    Keyes SR, Rockwell S, Sartorelli AC.
    Cancer Res; 1989 Jun 15; 49(12):3310-3. PubMed ID: 2470504
    [Abstract] [Full Text] [Related]

  • 5. Adducts of mitomycin C and DNA in EMT6 mouse mammary tumor cells: effects of hypoxia and dicumarol on adduct patterns.
    Bizanek R, Chowdary D, Arai H, Kasai M, Hughes CS, Sartorelli AC, Rockwell S, Tomasz M.
    Cancer Res; 1993 Nov 01; 53(21):5127-34. PubMed ID: 7693331
    [Abstract] [Full Text] [Related]

  • 6. Porfiromycin as a bioreductive alkylating agent with selective toxicity to hypoxic EMT6 tumor cells in vivo and in vitro.
    Keyes SR, Rockwell S, Sartorelli AC.
    Cancer Res; 1985 Aug 01; 45(8):3642-5. PubMed ID: 3926306
    [Abstract] [Full Text] [Related]

  • 7. Correlation between drug uptake and selective toxicity of porfiromycin to hypoxic EMT6 cells.
    Keyes SR, Rockwell S, Sartorelli AC.
    Cancer Res; 1987 Nov 01; 47(21):5654-7. PubMed ID: 3664473
    [Abstract] [Full Text] [Related]

  • 8. Formation of a major DNA adduct of the mitomycin metabolite 2,7-diaminomitosene in EMT6 mouse mammary tumor cells treated with mitomycin C.
    Palom Y, Belcourt MF, Kumar GS, Arai H, Kasai M, Sartorelli AC, Rockwell S, Tomasz M.
    Oncol Res; 1998 Nov 01; 10(10):509-21. PubMed ID: 10338154
    [Abstract] [Full Text] [Related]

  • 9. Studies on the mechanism of the cytotoxic action of the mitomycin antibiotics in hypoxic and oxygenated EMT6 cells.
    Sartorelli AC, Tomasz M, Rockwell S.
    Adv Enzyme Regul; 1993 Nov 01; 33():3-17. PubMed ID: 8356915
    [Abstract] [Full Text] [Related]

  • 10. Cytotoxicity and DNA crosslinks produced by mitomycin analogs in aerobic and hypoxic EMT6 cells.
    Keyes SR, Loomis R, DiGiovanna MP, Pritsos CA, Rockwell S, Sartorelli AC.
    Cancer Commun; 1991 Nov 01; 3(10-11):351-6. PubMed ID: 1760250
    [Abstract] [Full Text] [Related]

  • 11. Oxygen and exposure kinetics as factors influencing the cytotoxicity of porfiromycin, a mitomycin C analogue, in Chinese hamster ovary cells.
    Marshall RS, Rauth AM.
    Cancer Res; 1988 Oct 15; 48(20):5655-9. PubMed ID: 3167822
    [Abstract] [Full Text] [Related]

  • 12. Chemotherapeutic attack of hypoxic tumor cells by the bioreductive alkylating agent mitomycin C.
    Keyes SR, Heimbrook DC, Fracasso PM, Rockwell S, Sligar SG, Sartorelli AC.
    Adv Enzyme Regul; 1985 Oct 15; 23():291-307. PubMed ID: 3934922
    [Abstract] [Full Text] [Related]

  • 13. Cytotoxic potential of monoalkylation products between mitomycins and DNA: studies of decarbamoyl mitomycin C in wild-type and repair-deficient cell lines.
    Kim SY, Rockwell S.
    Oncol Res; 1995 Oct 15; 7(5):39-47. PubMed ID: 8534933
    [Abstract] [Full Text] [Related]

  • 14. Cytotoxic potential of monoalkylation products between mitomycins and DNA: studies of decarbamoyl mitomycin C in wild-type and repair-deficient cell lines.
    Rockwell S, Kim SY.
    Oncol Res; 1995 Oct 15; 7(1):39-47. PubMed ID: 7549043
    [Abstract] [Full Text] [Related]

  • 15. Enhancement of mitomycin C cytotoxicity to hypoxic tumor cells by dicoumarol in vivo and in vitro.
    Keyes SR, Rockwell S, Sartorelli AC.
    Cancer Res; 1985 Jan 15; 45(1):213-6. PubMed ID: 2578093
    [Abstract] [Full Text] [Related]

  • 16. Modulation of the cytotoxicity of porfiromycin by dicoumarol in vitro and in vivo.
    Rockwell S, Keyes SR, Sartorelli AC.
    Anticancer Res; 1989 Jan 15; 9(4):817-20. PubMed ID: 2479329
    [Abstract] [Full Text] [Related]

  • 17. Effect of deficiencies in DNA repair on the toxicity of mitomycin C and porfiromycin to CHO cells under aerobic and hypoxic conditions.
    Hughes CS, Irvin CG, Rockwell S.
    Cancer Commun; 1991 Feb 15; 3(2):29-35. PubMed ID: 1899798
    [Abstract] [Full Text] [Related]

  • 18. Metabolism of bioreductive antitumor compounds by purified rat and human DT-diaphorases.
    Beall HD, Mulcahy RT, Siegel D, Traver RD, Gibson NW, Ross D.
    Cancer Res; 1994 Jun 15; 54(12):3196-201. PubMed ID: 8205540
    [Abstract] [Full Text] [Related]

  • 19. Interactions of mitomycin C with mammalian DNA detected by alkaline elution.
    Dorr RT, Bowden GT, Alberts DS, Liddil JD.
    Cancer Res; 1985 Aug 15; 45(8):3510-6. PubMed ID: 3926301
    [Abstract] [Full Text] [Related]

  • 20. pH dependence of mitomycin C-induced cross-linking activity in EMT6 tumor cells.
    Kennedy KA, McGurl JD, Leondaridis L, Alabaster O.
    Cancer Res; 1985 Aug 15; 45(8):3541-7. PubMed ID: 3926302
    [Abstract] [Full Text] [Related]

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