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Journal Abstract Search

576 related items for PubMed ID: 25599948

  • 1. Design and synthesis of pyrazole-oxindole conjugates targeting tubulin polymerization as new anticancer agents.
    Kamal A, Shaik AB, Jain N, Kishor C, Nagabhushana A, Supriya B, Bharath Kumar G, Chourasiya SS, Suresh Y, Mishra RK, Addlagatta A.
    Eur J Med Chem; 2015 Mar 06; 92():501-13. PubMed ID: 25599948
    [Abstract] [Full Text] [Related]

  • 2. Design, synthesis and biological evaluation of 1, 4-dihydro indeno[1,2-c] pyrazole linked oxindole analogues as potential anticancer agents targeting tubulin and inducing p53 dependent apoptosis.
    Khan I, Garikapati KR, Shaik AB, Makani VKK, Rahim A, Shareef MA, Reddy VG, Pal-Bhadra M, Kamal A, Kumar CG.
    Eur J Med Chem; 2018 Jan 20; 144():104-115. PubMed ID: 29268127
    [Abstract] [Full Text] [Related]

  • 3. Pyrazole-oxadiazole conjugates: synthesis, antiproliferative activity and inhibition of tubulin polymerization.
    Kamal A, Shaik AB, Polepalli S, Reddy VS, Kumar GB, Gupta S, Krishna KV, Nagabhushana A, Mishra RK, Jain N.
    Org Biomol Chem; 2014 Oct 28; 12(40):7993-8007. PubMed ID: 25181296
    [Abstract] [Full Text] [Related]

  • 4. Design and synthesis of pyrazole/isoxazole linked arylcinnamides as tubulin polymerization inhibitors and potential antiproliferative agents.
    Kamal A, Shaik AB, Rao BB, Khan I, Bharath Kumar G, Jain N.
    Org Biomol Chem; 2015 Oct 28; 13(40):10162-78. PubMed ID: 26303171
    [Abstract] [Full Text] [Related]

  • 5. Synthesis and biological evaluation of podophyllotoxin congeners as tubulin polymerization inhibitors.
    Kamal A, Srinivasa Reddy T, Polepalli S, Shalini N, Reddy VG, Subba Rao AV, Jain N, Shankaraiah N.
    Bioorg Med Chem; 2014 Oct 01; 22(19):5466-75. PubMed ID: 25131956
    [Abstract] [Full Text] [Related]

  • 6. Design, synthesis and biological evaluation of novel pyrazoline-containing derivatives as potential tubulin assembling inhibitors.
    Qin YJ, Li YJ, Jiang AQ, Yang MR, Zhu QZ, Dong H, Zhu HL.
    Eur J Med Chem; 2015 Apr 13; 94():447-57. PubMed ID: 25828827
    [Abstract] [Full Text] [Related]

  • 7. Design, Synthesis, and Biological Evaluation of 1-Methyl-1,4-dihydroindeno[1,2-c]pyrazole Analogues as Potential Anticancer Agents Targeting Tubulin Colchicine Binding Site.
    Liu YN, Wang JJ, Ji YT, Zhao GD, Tang LQ, Zhang CM, Guo XL, Liu ZP.
    J Med Chem; 2016 Jun 09; 59(11):5341-55. PubMed ID: 27172319
    [Abstract] [Full Text] [Related]

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  • 9. Synthesis, biological evaluation and molecular docking of benzimidazole grafted benzsulfamide-containing pyrazole ring derivatives as novel tubulin polymerization inhibitors.
    Wang YT, Shi TQ, Zhu HL, Liu CH.
    Bioorg Med Chem; 2019 Feb 01; 27(3):502-515. PubMed ID: 30606674
    [Abstract] [Full Text] [Related]

  • 10. Synthesis and Preclinical Evaluation of Indole Triazole Conjugates as Microtubule Targeting Agents that are Effective against MCF-7 Breast Cancer Cell Lines.
    Yele V, Pindiprolu SKSS, Sana S, Ramamurty DSVNM, Madasi JRK, Vadlamani S.
    Anticancer Agents Med Chem; 2021 Feb 01; 21(8):1047-1055. PubMed ID: 32981511
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  • 13. Synthesis and evaluation of new 2-chloro-4-aminopyrimidine and 2,6-dimethyl-4-aminopyrimidine derivatives as tubulin polymerization inhibitors.
    Xu S, An B, Li Y, Luo X, Li X, Jia X.
    Bioorg Med Chem Lett; 2018 Jun 01; 28(10):1769-1775. PubMed ID: 29673981
    [Abstract] [Full Text] [Related]

  • 14. New 6- and 7-heterocyclyl-1H-indole derivatives as potent tubulin assembly and cancer cell growth inhibitors.
    La Regina G, Bai R, Coluccia A, Naccarato V, Famiglini V, Nalli M, Masci D, Verrico A, Rovella P, Mazzoccoli C, Da Pozzo E, Cavallini C, Martini C, Vultaggio S, Dondio G, Varasi M, Mercurio C, Hamel E, Lavia P, Silvestri R.
    Eur J Med Chem; 2018 May 25; 152():283-297. PubMed ID: 29730191
    [Abstract] [Full Text] [Related]

  • 15. Design, synthesis and biological evaluation of a series of pyrano chalcone derivatives containing indole moiety as novel anti-tubulin agents.
    Wang G, Li C, He L, Lei K, Wang F, Pu Y, Yang Z, Cao D, Ma L, Chen J, Sang Y, Liang X, Xiang M, Peng A, Wei Y, Chen L.
    Bioorg Med Chem; 2014 Apr 01; 22(7):2060-79. PubMed ID: 24629450
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  • 16. Design, synthesis, and biological evaluation of novel combretastatin A-4 thio derivatives as microtubule targeting agents.
    Stefański T, Mikstacka R, Kurczab R, Dutkiewicz Z, Kucińska M, Murias M, Zielińska-Przyjemska M, Cichocki M, Teubert A, Kaczmarek M, Hogendorf A, Sobiak S.
    Eur J Med Chem; 2018 Jan 20; 144():797-816. PubMed ID: 29291446
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  • 17. Design, synthesis, and bioevaluation of pyrazolo[1,5-a]pyrimidine derivatives as tubulin polymerization inhibitors targeting the colchicine binding site with potent anticancer activities.
    Li G, Wang Y, Li L, Ren Y, Deng X, Liu J, Wang W, Luo M, Liu S, Chen J.
    Eur J Med Chem; 2020 Sep 15; 202():112519. PubMed ID: 32650183
    [Abstract] [Full Text] [Related]

  • 18. Synthesis and biological evaluation of 4-aza-2,3-dihydropyridophenanthrolines as tubulin polymerization inhibitors.
    Kamal A, Srinivasa Reddy T, Polepalli S, Paidakula S, Srinivasulu V, Ganga Reddy V, Jain N, Shankaraiah N.
    Bioorg Med Chem Lett; 2014 Aug 01; 24(15):3356-60. PubMed ID: 24953821
    [Abstract] [Full Text] [Related]

  • 19. Design and synthesis of 1,2,3-triazolo linked benzo[d]imidazo[2,1-b]thiazole conjugates as tubulin polymerization inhibitors.
    Shaik SP, Vishnuvardhan MVPS, Sultana F, Subba Rao AV, Bagul C, Bhattacharjee D, Kapure JS, Jain N, Kamal A.
    Bioorg Med Chem; 2017 Jul 01; 25(13):3285-3297. PubMed ID: 28462842
    [Abstract] [Full Text] [Related]

  • 20. Synthesis and biological evaluation of imidazo[2,1-b][1,3,4]thiadiazole-linked oxindoles as potent tubulin polymerization inhibitors.
    Kamal A, Rao MP, Das P, Swapna P, Polepalli S, Nimbarte VD, Mullagiri K, Kovvuri J, Jain N.
    ChemMedChem; 2014 Jul 01; 9(7):1463-75. PubMed ID: 24715721
    [Abstract] [Full Text] [Related]

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