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337 related items for PubMed ID: 2561940

  • 1. Multiple defects occur in the guanine nucleotide regulatory protein system in liver plasma membranes of obese (fa/fa) but not lean (Fa/Fa) Zucker rats: loss of functional Gi and abnormal Gs function.
    Houslay MD, Gawler DJ, Milligan G, Wilson A.
    Cell Signal; 1989; 1(1):9-22. PubMed ID: 2561940
    [Abstract] [Full Text] [Related]

  • 2. Determination of G-protein levels, ADP-ribosylation by cholera and pertussis toxins and the regulation of adenylyl cyclase activity in liver plasma membranes from lean and genetically diabetic (db/db) mice.
    Palmer TM, Houslay MD.
    Biochim Biophys Acta; 1991 Oct 21; 1097(3):193-204. PubMed ID: 1932144
    [Abstract] [Full Text] [Related]

  • 3. Changes in the phosphorylation state of the inhibitory guanine-nucleotide-binding protein Gi-2 in hepatocytes from lean (Fa/Fa) and obese (fa/fa) Zucker rats.
    Bushfield M, Pyne NJ, Houslay MD.
    Eur J Biochem; 1990 Sep 11; 192(2):537-42. PubMed ID: 2120055
    [Abstract] [Full Text] [Related]

  • 4. Evaluation of inhibitory guanine nucleotide regulatory protein Gi function in hepatocyte and liver membranes from obese Zucker (fa/fa) rats and their lean (Fa/?) littermates.
    Young P, Kirkham DM, Murphy GJ, Cawthorne MA.
    Diabetologia; 1991 Aug 11; 34(8):565-9. PubMed ID: 1936659
    [Abstract] [Full Text] [Related]

  • 5. Guanine nucleotide binding regulatory proteins and adenylate cyclase in livers of streptozotocin- and BB/Wor-diabetic rats. Immunodetection of Gs and Gi with antisera prepared against synthetic peptides.
    Lynch CJ, Blackmore PF, Johnson EH, Wange RL, Krone PK, Exton JH.
    J Clin Invest; 1989 Jun 11; 83(6):2050-62. PubMed ID: 2498395
    [Abstract] [Full Text] [Related]

  • 6. Insulin affects the ability of Gi to be ADP-ribosylated but does not elicit its phosphorylation in intact hepatocytes.
    Pyne NJ, Heyworth CM, Balfour NW, Houslay MD.
    Biochem Biophys Res Commun; 1989 Nov 30; 165(1):251-6. PubMed ID: 2511846
    [Abstract] [Full Text] [Related]

  • 7. Glucagon desensitization of adenylate cyclase and stimulation of inositol phospholipid metabolism does not involve the inhibitory guanine nucleotide regulatory protein Gi, which is inactivated upon challenge of hepatocytes with glucagon.
    Murphy GJ, Gawler DJ, Milligan G, Wakelam MJ, Pyne NJ, Houslay MD.
    Biochem J; 1989 Apr 01; 259(1):191-7. PubMed ID: 2497730
    [Abstract] [Full Text] [Related]

  • 8. G proteins in rat liver proliferation during cholestasis.
    Rodriguez-Henche N, Guijarro LG, Couvineau A, Carrero I, Arilla E, Laburthe M, Prieto JC.
    Hepatology; 1994 Oct 01; 20(4 Pt 1):1041-7. PubMed ID: 7927206
    [Abstract] [Full Text] [Related]

  • 9. The role of Gi and the membrane-fluidizing agent benzyl alcohol in modulating the hysteretic activation of human platelet adenylate cyclase by guanylyl 5'-imidodiphosphate.
    Spence S, Houslay MD.
    Biochem J; 1993 May 01; 291 ( Pt 3)(Pt 3):945-9. PubMed ID: 8489520
    [Abstract] [Full Text] [Related]

  • 10. The new positive inotrope sulmazole inhibits the function of guanine nucleotide regulatory proteins by affecting GTP turnover.
    Ramkumar V, Stiles GL.
    Mol Pharmacol; 1988 Dec 01; 34(6):761-8. PubMed ID: 2849044
    [Abstract] [Full Text] [Related]

  • 11. Quantification of the alpha and beta subunits of the transducing elements (Gs and Gi) of adenylate cyclase in adipocyte membranes from lean and obese (ob/ob) mice.
    Bégin-Heick N.
    Biochem J; 1990 May 15; 268(1):83-9. PubMed ID: 2160813
    [Abstract] [Full Text] [Related]

  • 12. Alterations in G-protein expression and the hormonal regulation of adenylate cyclase in the adipocytes of obese (fa/fa) Zucker rats.
    Strassheim D, Palmer T, Milligan G, Houslay MD.
    Biochem J; 1991 May 15; 276 ( Pt 1)(Pt 1):197-202. PubMed ID: 1903933
    [Abstract] [Full Text] [Related]

  • 13. Direct coupling of opioid receptors to both stimulatory and inhibitory guanine nucleotide-binding proteins in F-11 neuroblastoma-sensory neuron hybrid cells.
    Cruciani RA, Dvorkin B, Morris SA, Crain SM, Makman MH.
    Proc Natl Acad Sci U S A; 1993 Apr 01; 90(7):3019-23. PubMed ID: 8385355
    [Abstract] [Full Text] [Related]

  • 14. Diabetes abolishes the GTP-dependent, but not the receptor-dependent inhibitory function of the inhibitory guanine-nucleotide-binding regulatory protein (Gi) on adipocyte adenylate cyclase activity.
    Strassheim D, Milligan G, Houslay MD.
    Biochem J; 1990 Mar 01; 266(2):521-6. PubMed ID: 2156498
    [Abstract] [Full Text] [Related]

  • 15. Protein kinase C stimulates adenylate cyclase activity in prolactin-secreting rat adenoma (GH4C1) pituicytes by inactivating the inhibitory GTP-binding protein Gi.
    Gordeladze JO, Björo T, Torjesen PA, Ostberg BC, Haug E, Gautvik KM.
    Eur J Biochem; 1989 Aug 01; 183(2):397-406. PubMed ID: 2569396
    [Abstract] [Full Text] [Related]

  • 16. Possible involvement of pertussis toxin substrates (Gi, Go) in desipramine-induced refractoriness of adenylate cyclase in cerebral cortices of rats.
    Okada F, Tokumitsu Y, Ui M.
    J Neurochem; 1988 Jul 01; 51(1):194-9. PubMed ID: 3132531
    [Abstract] [Full Text] [Related]

  • 17. Alterations of adenylyl cyclase-linked G proteins in rat liver during aging.
    Eakes AT, Hymer TK, Rosenthal MJ, Moss J, Katz MS.
    Am J Physiol; 1996 Jan 01; 270(1 Pt 1):E126-32. PubMed ID: 8772484
    [Abstract] [Full Text] [Related]

  • 18. GTP binding regulatory proteins of adenylate cyclase in Schistosoma mansoni at different stages of development.
    Estey SJ, Mansour TE.
    Mol Biochem Parasitol; 1988 Jul 01; 30(1):67-75. PubMed ID: 3135495
    [Abstract] [Full Text] [Related]

  • 19. Metformin treatment of lean and obese Zucker rats modulates the ability of glucagon and insulin to regulate hepatocyte adenylate cyclase activity.
    Gawler DJ, Wilson A, Houslay MD.
    J Endocrinol; 1989 Jul 01; 122(1):207-12. PubMed ID: 2671238
    [Abstract] [Full Text] [Related]

  • 20. Diabetes-induced alterations in the expression, functioning and phosphorylation state of the inhibitory guanine nucleotide regulatory protein Gi-2 in hepatocytes.
    Bushfield M, Griffiths SL, Murphy GJ, Pyne NJ, Knowler JT, Milligan G, Parker PJ, Mollner S, Houslay MD.
    Biochem J; 1990 Oct 15; 271(2):365-72. PubMed ID: 1700700
    [Abstract] [Full Text] [Related]

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