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349 related items for PubMed ID: 25636517

  • 1. The STAT3 inhibitor WP1066 reverses the resistance of chronic lymphocytic leukemia cells to histone deacetylase inhibitors induced by interleukin-6.
    Lu K, Fang XS, Feng LL, Jiang YJ, Zhou XX, Liu X, Li PP, Chen N, Ding M, Wang N, Zhang J, Wang X.
    Cancer Lett; 2015 Apr 10; 359(2):250-8. PubMed ID: 25636517
    [Abstract] [Full Text] [Related]

  • 2. The STAT3 inhibitor WP1066 synergizes with vorinostat to induce apoptosis of mantle cell lymphoma cells.
    Lu K, Chen N, Zhou XX, Ge XL, Feng LL, Li PP, Li XY, Geng LY, Wang X.
    Biochem Biophys Res Commun; 2015 Aug 14; 464(1):292-8. PubMed ID: 26116769
    [Abstract] [Full Text] [Related]

  • 3. Bone marrow stroma-induced resistance of chronic lymphocytic leukemia cells to arsenic trioxide involves Mcl-1 upregulation and is overcome by inhibiting the PI3Kδ or PKCβ signaling pathways.
    Amigo-Jiménez I, Bailón E, Aguilera-Montilla N, Terol MJ, García-Marco JA, García-Pardo A.
    Oncotarget; 2015 Dec 29; 6(42):44832-48. PubMed ID: 26540567
    [Abstract] [Full Text] [Related]

  • 4. Effective elimination of chronic lymphocytic leukemia cells in the stromal microenvironment by a novel drug combination strategy using redox-mediated mechanisms.
    Zhang W, Pelicano H, Yin R, Zeng J, Wen T, Ding L, Huang R.
    Mol Med Rep; 2015 Nov 29; 12(5):7374-88. PubMed ID: 26458979
    [Abstract] [Full Text] [Related]

  • 5. Trichostatin A effectively induces apoptosis in chronic lymphocytic leukemia cells via inhibition of Wnt signaling and histone deacetylation.
    Peiffer L, Poll-Wolbeck SJ, Flamme H, Gehrke I, Hallek M, Kreuzer KA.
    J Cancer Res Clin Oncol; 2014 Aug 29; 140(8):1283-93. PubMed ID: 24793644
    [Abstract] [Full Text] [Related]

  • 6. A novel inhibitor of the STAT3 pathway induces apoptosis in malignant glioma cells both in vitro and in vivo.
    Iwamaru A, Szymanski S, Iwado E, Aoki H, Yokoyama T, Fokt I, Hess K, Conrad C, Madden T, Sawaya R, Kondo S, Priebe W, Kondo Y.
    Oncogene; 2007 Apr 12; 26(17):2435-44. PubMed ID: 17043651
    [Abstract] [Full Text] [Related]

  • 7. The JAK3-selective inhibitor PF-956980 reverses the resistance to cytotoxic agents induced by interleukin-4 treatment of chronic lymphocytic leukemia cells: potential for reversal of cytoprotection by the microenvironment.
    Steele AJ, Prentice AG, Cwynarski K, Hoffbrand AV, Hart SM, Lowdell MW, Samuel ER, Wickremasinghe RG.
    Blood; 2010 Nov 25; 116(22):4569-77. PubMed ID: 20716767
    [Abstract] [Full Text] [Related]

  • 8. STAT3 and NF-κB cooperatively control in vitro spontaneous apoptosis and poor chemo-responsiveness in patients with chronic lymphocytic leukemia.
    Liu FT, Jia L, Wang P, Wang H, Farren TW, Agrawal SG.
    Oncotarget; 2016 May 31; 7(22):32031-45. PubMed ID: 27074565
    [Abstract] [Full Text] [Related]

  • 9. STAT3-induced SMYD3 transcription enhances chronic lymphocytic leukemia cell growth in vitro and in vivo.
    Lin F, Wu D, Fang D, Chen Y, Zhou H, Ou C.
    Inflamm Res; 2019 Sep 31; 68(9):739-749. PubMed ID: 31218443
    [Abstract] [Full Text] [Related]

  • 10. CD126 and Targeted Therapy with Tocilizumab in Chronic Lymphocytic Leukemia.
    Liu FT, Jia L, Wang P, Farren T, Li H, Hao X, Agrawal SG.
    Clin Cancer Res; 2016 May 15; 22(10):2462-9. PubMed ID: 26712690
    [Abstract] [Full Text] [Related]

  • 11. Histone deacetylase inhibitors increase microRNA-146a expression and enhance negative regulation of interleukin-1β signaling in osteoarthritis fibroblast-like synoviocytes.
    Wang JH, Shih KS, Wu YW, Wang AW, Yang CR.
    Osteoarthritis Cartilage; 2013 Dec 15; 21(12):1987-96. PubMed ID: 24107356
    [Abstract] [Full Text] [Related]

  • 12. Chronic lymphocytic leukemia cells induce anti-apoptotic effects of bone marrow stroma.
    Plander M, Ugocsai P, Seegers S, Orsó E, Reichle A, Schmitz G, Hofstädter F, Brockhoff G.
    Ann Hematol; 2011 Dec 15; 90(12):1381-90. PubMed ID: 21465189
    [Abstract] [Full Text] [Related]

  • 13. DNA damage response and anti-apoptotic proteins predict radiosensitization efficacy of HDAC inhibitors SAHA and LBH589 in patient-derived glioblastoma cells.
    Pont LM, Naipal K, Kloezeman JJ, Venkatesan S, van den Bent M, van Gent DC, Dirven CM, Kanaar R, Lamfers ML, Leenstra S.
    Cancer Lett; 2015 Jan 28; 356(2 Pt B):525-35. PubMed ID: 25305451
    [Abstract] [Full Text] [Related]

  • 14. The HDAC inhibitor, panobinostat, induces apoptosis by suppressing the expresssion of specificity protein 1 in oral squamous cell carcinoma.
    Jeon YJ, Ko SM, Cho JH, Chae JI, Shim JH.
    Int J Mol Med; 2013 Oct 28; 32(4):860-6. PubMed ID: 23877235
    [Abstract] [Full Text] [Related]

  • 15. Inhibitor of signal transducer and activator of transcription 3 (STAT3) suppresses ovarian cancer growth, migration and invasion and enhances the effect of cisplatin in vitro.
    Tang YJ, Sun ZL, Wu WG, Xing J, He YF, Xin DM, Han P.
    Genet Mol Res; 2015 Mar 30; 14(1):2450-60. PubMed ID: 25867391
    [Abstract] [Full Text] [Related]

  • 16. Analysis of apoptosis regulatory genes altered by histone deacetylase inhibitors in chronic lymphocytic leukemia cells.
    Pérez-Perarnau A, Coll-Mulet L, Rubio-Patiño C, Iglesias-Serret D, Cosialls AM, González-Gironès DM, de Frias M, de Sevilla AF, de la Banda E, Pons G, Gil J.
    Epigenetics; 2011 Oct 01; 6(10):1228-35. PubMed ID: 21931276
    [Abstract] [Full Text] [Related]

  • 17. Adhesion of ZAP-70+ chronic lymphocytic leukemia cells to stromal cells is enhanced by cytokines and blocked by inhibitors of the PI3-kinase pathway.
    Lafarge ST, Johnston JB, Gibson SB, Marshall AJ.
    Leuk Res; 2014 Jan 01; 38(1):109-15. PubMed ID: 23981382
    [Abstract] [Full Text] [Related]

  • 18. STAT3 inhibitor WP1066 attenuates miRNA-21 to suppress human oral squamous cell carcinoma growth in vitro and in vivo.
    Zhou X, Ren Y, Liu A, Han L, Zhang K, Li S, Li P, Li P, Kang C, Wang X, Zhang L.
    Oncol Rep; 2014 May 01; 31(5):2173-80. PubMed ID: 24676554
    [Abstract] [Full Text] [Related]

  • 19. [Study of Kinase Inhibitor WP1066 on the STAT3/JAK2 of Prostate Stromal Cells].
    Li YX, Li JM, Wei Q, Zhang ZP, Wu J, Wang AG.
    Sichuan Da Xue Xue Bao Yi Xue Ban; 2018 Jan 01; 49(1):65-68. PubMed ID: 29737092
    [Abstract] [Full Text] [Related]

  • 20. Histone deacetylase inhibitors in plasma cell leukemia treatment: effect of bone marrow microenvironment.
    Burianova I, Kuzelova K, Mitrovsky O, Spicka I, Stockbauer P, Zackova M.
    Neoplasma; 2017 Jan 01; 64(2):228-237. PubMed ID: 28043150
    [Abstract] [Full Text] [Related]

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