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Journal Abstract Search

436 related items for PubMed ID: 25648320

  • 1. Discovery of Akt kinase inhibitors through structure-based virtual screening and their evaluation as potential anticancer agents.
    Chuang CH, Cheng TC, Leu YL, Chuang KH, Tzou SC, Chen CS.
    Int J Mol Sci; 2015 Feb 02; 16(2):3202-12. PubMed ID: 25648320
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  • 2. Docking of protein kinase B inhibitors: implications in the structure-based optimization of a novel scaffold.
    Hernández-Campos A, Velázquez-Martínez I, Castillo R, López-Vallejo F, Jia P, Yu Y, Giulianotti MA, Medina-Franco JL.
    Chem Biol Drug Des; 2010 Sep 01; 76(3):269-76. PubMed ID: 20572809
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  • 3. Evaluation of novel Akt1 inhibitors as anticancer agents using virtual co-crystallized pharmacophore generation.
    Al-Sha'er MA, Mansi I, Almazari I, Hakooz N.
    J Mol Graph Model; 2015 Nov 01; 62():213-225. PubMed ID: 26485540
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  • 4. Discovery of a novel protein kinase B inhibitor by structure-based virtual screening.
    Medina-Franco JL, Giulianotti MA, Yu Y, Shen L, Yao L, Singh N.
    Bioorg Med Chem Lett; 2009 Aug 15; 19(16):4634-8. PubMed ID: 19604696
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  • 8. New thiazole carboxamides as potent inhibitors of Akt kinases.
    Chang S, Zhang Z, Zhuang X, Luo J, Cao X, Li H, Tu Z, Lu X, Ren X, Ding K.
    Bioorg Med Chem Lett; 2012 Jan 15; 22(2):1208-12. PubMed ID: 22172705
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  • 11. Discovery of 4-(Piperazin-1-yl)-7H-pyrrolo[2,3-d]pyrimidine Derivatives as Akt Inhibitors.
    Liu Y, Yin Y, Zhang J, Nomie K, Zhang L, Yang D, Wang ML, Zhao G.
    Arch Pharm (Weinheim); 2016 May 15; 349(5):356-62. PubMed ID: 26991997
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  • 14. Pharmacophore identification, virtual screening and biological evaluation of prenylated flavonoids derivatives as PKB/Akt1 inhibitors.
    Dong X, Zhou X, Jing H, Chen J, Liu T, Yang B, He Q, Hu Y.
    Eur J Med Chem; 2011 Dec 15; 46(12):5949-58. PubMed ID: 22027102
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  • 15. Discovery of pyrazolo[1,5-a]pyridines as p110α-selective PI3 kinase inhibitors.
    Kendall JD, O'Connor PD, Marshall AJ, Frédérick R, Marshall ES, Lill CL, Lee WJ, Kolekar S, Chao M, Malik A, Yu S, Chaussade C, Buchanan C, Rewcastle GW, Baguley BC, Flanagan JU, Jamieson SM, Denny WA, Shepherd PR.
    Bioorg Med Chem; 2012 Jan 01; 20(1):69-85. PubMed ID: 22177405
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  • 16. Synthesis and biological evaluation of imidazo[1,5-a]pyridine-benzimidazole hybrids as inhibitors of both tubulin polymerization and PI3K/Akt pathway.
    Kamal A, Rao AV, Nayak VL, Reddy NV, Swapna K, Ramakrishna G, Alvala M.
    Org Biomol Chem; 2014 Dec 28; 12(48):9864-80. PubMed ID: 25354805
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  • 19. Identification of green tea catechins as potent inhibitors of the polo-box domain of polo-like kinase 1.
    Shan HM, Shi Y, Quan J.
    ChemMedChem; 2015 Jan 28; 10(1):158-63. PubMed ID: 25196850
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  • 20. Discovery of spirocyclic sulfonamides as potent Akt inhibitors with exquisite selectivity against PKA.
    Xu R, Banka A, Blake JF, Mitchell IS, Wallace EM, Bencsik JR, Kallan NC, Spencer KL, Gloor SL, Martinson M, Risom T, Gross SD, Morales TH, Wu WI, Vigers GP, Brandhuber BJ, Skelton NJ.
    Bioorg Med Chem Lett; 2011 Apr 15; 21(8):2335-40. PubMed ID: 21420856
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