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Journal Abstract Search

254 related items for PubMed ID: 25650314

  • 1. Using click chemistry toward novel 1,2,3-triazole-linked dopamine D3 receptor ligands.
    Keck TM, Banala AK, Slack RD, Burzynski C, Bonifazi A, Okunola-Bakare OM, Moore M, Deschamps JR, Rais R, Slusher BS, Newman AH.
    Bioorg Med Chem; 2015 Jul 15; 23(14):4000-12. PubMed ID: 25650314
    [Abstract] [Full Text] [Related]

  • 2. A single glycine in extracellular loop 1 is the critical determinant for pharmacological specificity of dopamine D2 and D3 receptors.
    Michino M, Donthamsetti P, Beuming T, Banala A, Duan L, Roux T, Han Y, Trinquet E, Newman AH, Javitch JA, Shi L.
    Mol Pharmacol; 2013 Dec 15; 84(6):854-64. PubMed ID: 24061855
    [Abstract] [Full Text] [Related]

  • 3. Synthesis and evaluation of arylpiperazine-reverse amides as biased dopamine D3 receptor ligands.
    Cao Y, Paudel S, Zhang X, Kim KM, Cheon SH.
    Bioorg Med Chem; 2015 Sep 01; 23(17):5264-72. PubMed ID: 26278029
    [Abstract] [Full Text] [Related]

  • 4. Investigation of the binding and functional properties of extended length D3 dopamine receptor-selective antagonists.
    Furman CA, Roof RA, Moritz AE, Miller BN, Doyle TB, Free RB, Banala AK, Paul NM, Kumar V, Sibley CD, Newman AH, Sibley DR.
    Eur Neuropsychopharmacol; 2015 Sep 01; 25(9):1448-61. PubMed ID: 25583363
    [Abstract] [Full Text] [Related]

  • 5. The Significance of Chirality in Drug Design and Synthesis of Bitopic Ligands as D3 Receptor (D3R) Selective Agonists.
    Battiti FO, Cemaj SL, Guerrero AM, Shaik AB, Lam J, Rais R, Slusher BS, Deschamps JR, Imler GH, Newman AH, Bonifazi A.
    J Med Chem; 2019 Jul 11; 62(13):6287-6314. PubMed ID: 31257877
    [Abstract] [Full Text] [Related]

  • 6. Synthesis, pharmacological evaluation and molecular modeling studies of triazole containing dopamine D3 receptor ligands.
    Peng X, Wang Q, Mishra Y, Xu J, Reichert DE, Malik M, Taylor M, Luedtke RR, Mach RH.
    Bioorg Med Chem Lett; 2015 Feb 01; 25(3):519-23. PubMed ID: 25556097
    [Abstract] [Full Text] [Related]

  • 7. N-(3-fluoro-4-(4-(2-methoxy or 2,3-dichlorophenyl)piperazine-1-yl)butyl)arylcarboxamides as selective dopamine D3 receptor ligands: critical role of the carboxamide linker for D3 receptor selectivity.
    Banala AK, Levy BA, Khatri SS, Furman CA, Roof RA, Mishra Y, Griffin SA, Sibley DR, Luedtke RR, Newman AH.
    J Med Chem; 2011 May 26; 54(10):3581-94. PubMed ID: 21495689
    [Abstract] [Full Text] [Related]

  • 8. Synthesis and Pharmacological Characterization of Novel trans-Cyclopropylmethyl-Linked Bivalent Ligands That Exhibit Selectivity and Allosteric Pharmacology at the Dopamine D3 Receptor (D3R).
    Kumar V, Moritz AE, Keck TM, Bonifazi A, Ellenberger MP, Sibley CD, Free RB, Shi L, Lane JR, Sibley DR, Newman AH.
    J Med Chem; 2017 Feb 23; 60(4):1478-1494. PubMed ID: 28186762
    [Abstract] [Full Text] [Related]

  • 9. Chirality of Novel Bitopic Agonists Determines Unique Pharmacology at the Dopamine D3 Receptor.
    Adhikari P, Xie B, Semeano A, Bonifazi A, Battiti FO, Newman AH, Yano H, Shi L.
    Biomolecules; 2021 Apr 13; 11(4):. PubMed ID: 33924613
    [Abstract] [Full Text] [Related]

  • 10. Targeting the dopamine D3 receptor: an overview of drug design strategies.
    Cortés A, Moreno E, Rodríguez-Ruiz M, Canela EI, Casadó V.
    Expert Opin Drug Discov; 2016 Jul 13; 11(7):641-64. PubMed ID: 27135354
    [Abstract] [Full Text] [Related]

  • 11. Design, synthesis, and biological evaluation of structurally constrained hybrid analogues containing ropinirole moiety as a novel class of potent and selective dopamine D3 receptor ligands.
    Zhou B, Hong KH, Ji M, Cai J.
    Chem Biol Drug Des; 2018 Sep 13; 92(3):1597-1609. PubMed ID: 29710404
    [Abstract] [Full Text] [Related]

  • 12. Structure-based ligand discovery targeting orthosteric and allosteric pockets of dopamine receptors.
    Lane JR, Chubukov P, Liu W, Canals M, Cherezov V, Abagyan R, Stevens RC, Katritch V.
    Mol Pharmacol; 2013 Dec 13; 84(6):794-807. PubMed ID: 24021214
    [Abstract] [Full Text] [Related]

  • 13. Design, synthesis and evaluation of bitopic arylpiperazinephenyl-1,2,4-oxadiazoles as preferential dopamine D3 receptor ligands.
    Cao Y, Min C, Acharya S, Kim KM, Cheon SH.
    Bioorg Med Chem; 2016 Jan 15; 24(2):191-200. PubMed ID: 26707842
    [Abstract] [Full Text] [Related]

  • 14. Molecular determinants of selectivity and efficacy at the dopamine D3 receptor.
    Newman AH, Beuming T, Banala AK, Donthamsetti P, Pongetti K, LaBounty A, Levy B, Cao J, Michino M, Luedtke RR, Javitch JA, Shi L.
    J Med Chem; 2012 Aug 09; 55(15):6689-99. PubMed ID: 22632094
    [Abstract] [Full Text] [Related]

  • 15. Click chemistry based synthesis of dopamine D4 selective receptor ligands for the selection of potential PET tracers.
    Banerjee A, Maschauer S, Hübner H, Gmeiner P, Prante O.
    Bioorg Med Chem Lett; 2013 Nov 15; 23(22):6079-82. PubMed ID: 24100078
    [Abstract] [Full Text] [Related]

  • 16. Parallel synthesis and biological screening of dopamine receptor ligands taking advantage of a click chemistry based BAL linker.
    Bettinetti L, Löber S, Hübner H, Gmeiner P.
    J Comb Chem; 2005 Nov 15; 7(2):309-16. PubMed ID: 15762761
    [Abstract] [Full Text] [Related]

  • 17. Synthesis and binding affinity of new 1,4-disubstituted triazoles as potential dopamine D(3) receptor ligands.
    Insua I, Alvarado M, Masaguer CF, Iglesias A, Brea J, Loza MI, Carro L.
    Bioorg Med Chem Lett; 2013 Oct 15; 23(20):5586-91. PubMed ID: 24012118
    [Abstract] [Full Text] [Related]

  • 18. Exploration of the amine terminus in a novel series of 1,2,4-triazolo-3-yl-azabicyclo[3.1.0]hexanes as selective dopamine D3 receptor antagonists.
    Micheli F, Arista L, Bertani B, Braggio S, Capelli AM, Cremonesi S, Di-Fabio R, Gelardi G, Gentile G, Marchioro C, Pasquarello A, Provera S, Tedesco G, Tarsi L, Terreni S, Worby A, Heidbreder C.
    J Med Chem; 2010 Oct 14; 53(19):7129-39. PubMed ID: 20839775
    [Abstract] [Full Text] [Related]

  • 19. Selectivity optimization of substituted 1,2,3-triazoles as α7 nicotinic acetylcholine receptor agonists.
    Arunrungvichian K, Fokin VV, Vajragupta O, Taylor P.
    ACS Chem Neurosci; 2015 Aug 19; 6(8):1317-30. PubMed ID: 25932897
    [Abstract] [Full Text] [Related]

  • 20. Neuronal Dopamine D3 Receptors: Translational Implications for Preclinical Research and CNS Disorders.
    Kiss B, Laszlovszky I, Krámos B, Visegrády A, Bobok A, Lévay G, Lendvai B, Román V.
    Biomolecules; 2021 Jan 14; 11(1):. PubMed ID: 33466844
    [Abstract] [Full Text] [Related]

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