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705 related items for PubMed ID: 25653196

  • 1. EGF‑stimulated AKT activation is mediated by EGFR recycling via an early endocytic pathway in a gefitinib‑resistant human lung cancer cell line.
    Nishimura Y, Takiguchi S, Ito S, Itoh K.
    Int J Oncol; 2015 Apr; 46(4):1721-9. PubMed ID: 25653196
    [Abstract] [Full Text] [Related]

  • 2. Silencing of SNX1 by siRNA stimulates the ligand-induced endocytosis of EGFR and increases EGFR phosphorylation in gefitinib-resistant human lung cancer cell lines.
    Nishimura Y, Takiguchi S, Yoshioka K, Nakabeppu Y, Itoh K.
    Int J Oncol; 2012 Oct; 41(4):1520-30. PubMed ID: 22859339
    [Abstract] [Full Text] [Related]

  • 3. Evidence that depletion of the sorting nexin 1 by siRNA promotes HGF-induced MET endocytosis and MET phosphorylation in a gefitinib-resistant human lung cancer cell line.
    Nishimura Y, Takiguchi S, Ito S, Itoh K.
    Int J Oncol; 2014 Feb; 44(2):412-26. PubMed ID: 24297483
    [Abstract] [Full Text] [Related]

  • 4. Evidence for efficient phosphorylation of EGFR and rapid endocytosis of phosphorylated EGFR via the early/late endocytic pathway in a gefitinib-sensitive non-small cell lung cancer cell line.
    Nishimura Y, Yoshioka K, Bereczky B, Itoh K.
    Mol Cancer; 2008 May 21; 7():42. PubMed ID: 18492291
    [Abstract] [Full Text] [Related]

  • 5. The EGFR inhibitor gefitinib suppresses ligand-stimulated endocytosis of EGFR via the early/late endocytic pathway in non-small cell lung cancer cell lines.
    Nishimura Y, Bereczky B, Ono M.
    Histochem Cell Biol; 2007 May 21; 127(5):541-53. PubMed ID: 17361439
    [Abstract] [Full Text] [Related]

  • 6. Ephedrae herba stimulates hepatocyte growth factor-induced MET endocytosis and downregulation via early/late endocytic pathways in gefitinib-resistant human lung cancer cells.
    Nishimura Y, Hyuga S, Takiguchi S, Hyuga M, Itoh K, Hanawa T.
    Int J Oncol; 2016 May 21; 48(5):1895-906. PubMed ID: 26983447
    [Abstract] [Full Text] [Related]

  • 7. Gastrin-releasing peptide activates Akt through the epidermal growth factor receptor pathway and abrogates the effect of gefitinib.
    Liu X, Carlisle DL, Swick MC, Gaither-Davis A, Grandis JR, Siegfried JM.
    Exp Cell Res; 2007 Apr 15; 313(7):1361-72. PubMed ID: 17349623
    [Abstract] [Full Text] [Related]

  • 8. Differential roles of ERK and Akt pathways in regulation of EGFR-mediated signaling and motility in prostate cancer cells.
    Gan Y, Shi C, Inge L, Hibner M, Balducci J, Huang Y.
    Oncogene; 2010 Sep 02; 29(35):4947-58. PubMed ID: 20562913
    [Abstract] [Full Text] [Related]

  • 9. Activated Src and Ras induce gefitinib resistance by activation of signaling pathways downstream of epidermal growth factor receptor in human gallbladder adenocarcinoma cells.
    Qin B, Ariyama H, Baba E, Tanaka R, Kusaba H, Harada M, Nakano S.
    Cancer Chemother Pharmacol; 2006 Nov 02; 58(5):577-84. PubMed ID: 16532343
    [Abstract] [Full Text] [Related]

  • 10. Resistance to small molecule inhibitors of epidermal growth factor receptor in malignant gliomas.
    Li B, Chang CM, Yuan M, McKenna WG, Shu HK.
    Cancer Res; 2003 Nov 01; 63(21):7443-50. PubMed ID: 14612544
    [Abstract] [Full Text] [Related]

  • 11. Prostaglandin E2 upregulates EGF-stimulated signaling in mitogenic pathways involving Akt and ERK in hepatocytes.
    Dajani OF, Meisdalen K, Guren TK, Aasrum M, Tveteraas IH, Lilleby P, Thoresen GH, Sandnes D, Christoffersen T.
    J Cell Physiol; 2008 Feb 01; 214(2):371-80. PubMed ID: 17654493
    [Abstract] [Full Text] [Related]

  • 12. Knockdown of the Bcl-2 gene increases sensitivity to EGFR tyrosine kinase inhibitors in the H1975 lung cancer cell line harboring T790M mutation.
    Zou M, Xia S, Zhuang L, Han N, Chu Q, Chao T, Peng P, Chen Y, Gui Q, Yu S.
    Int J Oncol; 2013 Jun 01; 42(6):2094-102. PubMed ID: 23588221
    [Abstract] [Full Text] [Related]

  • 13. A novel role of Rho-kinase in the regulation of ligand-induced phosphorylated EGFR endocytosis via the early/late endocytic pathway in human fibrosarcoma cells.
    Nishimura Y, Bereczky B, Yoshioka K, Taniguchi S, Itoh K.
    J Mol Histol; 2011 Oct 01; 42(5):427-42. PubMed ID: 21847509
    [Abstract] [Full Text] [Related]

  • 14. Transient PI3K inhibition induces apoptosis and overcomes HGF-mediated resistance to EGFR-TKIs in EGFR mutant lung cancer.
    Donev IS, Wang W, Yamada T, Li Q, Takeuchi S, Matsumoto K, Yamori T, Nishioka Y, Sone S, Yano S.
    Clin Cancer Res; 2011 Apr 15; 17(8):2260-9. PubMed ID: 21220474
    [Abstract] [Full Text] [Related]

  • 15. Synergistic inhibition of cell migration by tetraspanin CD82 and gangliosides occurs via the EGFR or cMet-activated Pl3K/Akt signalling pathway.
    Li Y, Huang X, Zhang J, Li Y, Ma K.
    Int J Biochem Cell Biol; 2013 Nov 15; 45(11):2349-58. PubMed ID: 23968914
    [Abstract] [Full Text] [Related]

  • 16. Re-localization of activated EGF receptor and its signal transducers to multivesicular compartments downstream of early endosomes in response to EGF.
    Oksvold MP, Skarpen E, Wierød L, Paulsen RE, Huitfeldt HS.
    Eur J Cell Biol; 2001 Apr 15; 80(4):285-94. PubMed ID: 11370743
    [Abstract] [Full Text] [Related]

  • 17. Combined inhibition of IGFR enhances the effects of gefitinib in H1650: a lung cancer cell line with EGFR mutation and primary resistance to EGFR-TK inhibitors.
    Choi YJ, Rho JK, Jeon BS, Choi SJ, Park SC, Lee SS, Kim HR, Kim CH, Lee JC.
    Cancer Chemother Pharmacol; 2010 Jul 15; 66(2):381-8. PubMed ID: 19921194
    [Abstract] [Full Text] [Related]

  • 18. Role of somatostatin receptor 1 and 5 on epidermal growth factor receptor mediated signaling.
    Kharmate G, Rajput PS, Watt HL, Somvanshi RK, Chaudhari N, Qiu X, Kumar U.
    Biochim Biophys Acta; 2011 Jun 15; 1813(6):1172-89. PubMed ID: 21419811
    [Abstract] [Full Text] [Related]

  • 19. Dimerization and the signal transduction pathway of a small in-frame deletion in the epidermal growth factor receptor.
    Sakai K, Arao T, Shimoyama T, Murofushi K, Sekijima M, Kaji N, Tamura T, Saijo N, Nishio K.
    FASEB J; 2006 Feb 15; 20(2):311-3. PubMed ID: 16373402
    [Abstract] [Full Text] [Related]

  • 20. Sorting nexin 2-mediated membrane trafficking of c-Met contributes to sensitivity of molecular-targeted drugs.
    Ogi S, Fujita H, Kashihara M, Yamamoto C, Sonoda K, Okamoto I, Nakagawa K, Ohdo S, Tanaka Y, Kuwano M, Ono M.
    Cancer Sci; 2013 May 15; 104(5):573-83. PubMed ID: 23360489
    [Abstract] [Full Text] [Related]

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