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Journal Abstract Search

122 related items for PubMed ID: 2566467

  • 1. Inhibition of 3-methylindole bioactivation by the cytochrome P-450 suicide substrates 1-aminobenzotriazole and alpha-methylbenzylaminobenzotriazole.
    Huijzer JC, Adams JD, Jaw JY, Yost GS.
    Drug Metab Dispos; 1989; 17(1):37-42. PubMed ID: 2566467
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  • 2. N-alkylaminobenzotriazoles as isozyme-selective suicide inhibitors of rabbit pulmonary microsomal cytochrome P-450.
    Mathews JM, Bend JR.
    Mol Pharmacol; 1986 Jul; 30(1):25-32. PubMed ID: 3724742
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  • 3. N-aralkylated derivatives of 1-aminobenzotriazole are potent isozyme- and lung-selective mechanism-based inhibitors of guinea pig cytochrome P-450 in vivo.
    Knickle LC, Philpot RM, Bend JR.
    J Pharmacol Exp Ther; 1994 Jul; 270(1):377-85. PubMed ID: 8035335
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  • 4. Three N-aralkylated derivatives of 1-aminobenzotriazole as potent and isozyme-selective, mechanism-based inhibitors of guinea pig pulmonary cytochrome P-450 in vitro.
    Woodcroft KJ, Szczepan EW, Knickle LC, Bend JR.
    Drug Metab Dispos; 1990 Jul; 18(6):1031-7. PubMed ID: 1981509
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  • 5. Metabolism of the cytochrome P450 mechanism-based inhibitor N-benzyl-1-aminobenzotriazole to products that covalently bind with protein in guinea pig liver and lung microsomes: comparative study with 1-aminobenzotriazole.
    Woodcroft KJ, Webb CD, Yao M, Weedon AC, Bend JR.
    Chem Res Toxicol; 1997 May; 10(5):589-99. PubMed ID: 9168258
    [Abstract] [Full Text] [Related]

  • 6. Kinetics and selectivity of mechanism-based inhibition of guinea pig hepatic and pulmonary cytochrome P450 by N-benzyl-1-aminobenzotriazole and N-alpha-methylbenzyl-1-aminobenzotriazole.
    Sinal CJ, Bend JR.
    Drug Metab Dispos; 1996 Sep; 24(9):996-1001. PubMed ID: 8886610
    [Abstract] [Full Text] [Related]

  • 7. Metabolism of 3-methylindole in human tissues.
    Ruangyuttikarn W, Appleton ML, Yost GS.
    Drug Metab Dispos; 1991 Sep; 19(5):977-84. PubMed ID: 1686246
    [Abstract] [Full Text] [Related]

  • 8. N-aralkyl derivatives of 1-aminobenzotriazole as potent isozyme-selective mechanism-based inhibitors of rabbit pulmonary cytochrome P450 in vivo.
    Mathews JM, Bend JR.
    J Pharmacol Exp Ther; 1993 Apr; 265(1):281-5. PubMed ID: 8474011
    [Abstract] [Full Text] [Related]

  • 9. Inactivation of rabbit pulmonary cytochrome P-450 in microsomes and isolated perfused lungs by the suicide substrate 1-aminobenzotriazole.
    Mathews JM, Dostal LA, Bend JR.
    J Pharmacol Exp Ther; 1985 Oct; 235(1):186-90. PubMed ID: 4045721
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  • 10. Mechanistic studies on the cytochrome P450-catalyzed dehydrogenation of 3-methylindole.
    Skiles GL, Yost GS.
    Chem Res Toxicol; 1996 Oct; 9(1):291-7. PubMed ID: 8924606
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  • 18. Evidence supporting the formation of 2,3-epoxy-3-methylindoline: a reactive intermediate of the pneumotoxin 3-methylindole.
    Skordos KW, Skiles GL, Laycock JD, Lanza DL, Yost GS.
    Chem Res Toxicol; 1998 Jul; 11(7):741-9. PubMed ID: 9671536
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  • 19. Metabolism and bioactivation of 3-methylindole by Clara cells, alveolar macrophages, and subcellular fractions from rabbit lungs.
    Thornton-Manning JR, Nichols WK, Manning BW, Skiles GL, Yost GS.
    Toxicol Appl Pharmacol; 1993 Oct; 122(2):182-90. PubMed ID: 8212000
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  • 20. Cloning and expression of CYP2F3, a cytochrome P450 that bioactivates the selective pneumotoxins 3-methylindole and naphthalene.
    Wang H, Lanza DL, Yost GS.
    Arch Biochem Biophys; 1998 Jan 15; 349(2):329-40. PubMed ID: 9448722
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