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427 related items for PubMed ID: 25687757

  • 1. Differential roles for Bim and Nur77 in thymocyte clonal deletion induced by ubiquitous self-antigen.
    Hu QN, Baldwin TA.
    J Immunol; 2015 Mar 15; 194(6):2643-53. PubMed ID: 25687757
    [Abstract] [Full Text] [Related]

  • 2. BIM Deficiency Protects NOD Mice From Diabetes by Diverting Thymocytes to Regulatory T Cells.
    Krishnamurthy B, Chee J, Jhala G, Trivedi P, Catterall T, Selck C, Gurzov EN, Brodnicki TC, Graham KL, Wali JA, Zhan Y, Gray D, Strasser A, Allison J, Thomas HE, Kay TW.
    Diabetes; 2015 Sep 15; 64(9):3229-38. PubMed ID: 25948683
    [Abstract] [Full Text] [Related]

  • 3. Nur77 Regulates Nondeletional Mechanisms of Tolerance in T Cells.
    Hu QN, Suen AYW, Henao Caviedes LM, Baldwin TA.
    J Immunol; 2017 Nov 01; 199(9):3147-3157. PubMed ID: 28947542
    [Abstract] [Full Text] [Related]

  • 4. Proapoptotic protein Bim is differentially required during thymic clonal deletion to ubiquitous versus tissue-restricted antigens.
    Suen AY, Baldwin TA.
    Proc Natl Acad Sci U S A; 2012 Jan 17; 109(3):893-8. PubMed ID: 22215602
    [Abstract] [Full Text] [Related]

  • 5. Bim-mediated apoptosis is not necessary for thymic negative selection to ubiquitous self-antigens.
    Hu Q, Sader A, Parkman JC, Baldwin TA.
    J Immunol; 2009 Dec 15; 183(12):7761-7. PubMed ID: 19933852
    [Abstract] [Full Text] [Related]

  • 6. The BH3-only proteins Bim and Puma cooperate to impose deletional tolerance of organ-specific antigens.
    Gray DH, Kupresanin F, Berzins SP, Herold MJ, O'Reilly LA, Bouillet P, Strasser A.
    Immunity; 2012 Sep 21; 37(3):451-62. PubMed ID: 22960223
    [Abstract] [Full Text] [Related]

  • 7. Ligation of retinoic acid receptor alpha regulates negative selection of thymocytes by inhibiting both DNA binding of nur77 and synthesis of bim.
    Szegezdi E, Kiss I, Simon A, Blaskó B, Reichert U, Michel S, Sándor M, Fésüs L, Szondy Z.
    J Immunol; 2003 Apr 01; 170(7):3577-84. PubMed ID: 12646620
    [Abstract] [Full Text] [Related]

  • 8. Helios marks strongly autoreactive CD4+ T cells in two major waves of thymic deletion distinguished by induction of PD-1 or NF-κB.
    Daley SR, Hu DY, Goodnow CC.
    J Exp Med; 2013 Feb 11; 210(2):269-85. PubMed ID: 23337809
    [Abstract] [Full Text] [Related]

  • 9. Inhibition of Nur77/Nurr1 leads to inefficient clonal deletion of self-reactive T cells.
    Zhou T, Cheng J, Yang P, Wang Z, Liu C, Su X, Bluethmann H, Mountz JD.
    J Exp Med; 1996 Apr 01; 183(4):1879-92. PubMed ID: 8666944
    [Abstract] [Full Text] [Related]

  • 10. CBAP promotes thymocyte negative selection by facilitating T-cell receptor proximal signaling.
    Ho KC, Chiang YJ, Lai AC, Liao NS, Chang YJ, Yang-Yen HF, Yen JJ.
    Cell Death Dis; 2014 Nov 13; 5(11):e1518. PubMed ID: 25393474
    [Abstract] [Full Text] [Related]

  • 11. Loss of Bim results in abnormal accumulation of mature CD4-CD8-CD44-CD25- thymocytes.
    Hutcheson J, Perlman H.
    Immunobiology; 2007 Nov 13; 212(8):629-36. PubMed ID: 17869640
    [Abstract] [Full Text] [Related]

  • 12. A novel TCR transgenic model reveals that negative selection involves an immediate, Bim-dependent pathway and a delayed, Bim-independent pathway.
    Kovalovsky D, Pezzano M, Ortiz BD, Sant'Angelo DB.
    PLoS One; 2010 Jan 13; 5(1):e8675. PubMed ID: 20072628
    [Abstract] [Full Text] [Related]

  • 13. Strength of TCR signal from self-peptide modulates autoreactive thymocyte deletion and Foxp3(+) Treg-cell formation.
    Caton AJ, Kropf E, Simons DM, Aitken M, Weissler KA, Jordan MS.
    Eur J Immunol; 2014 Mar 13; 44(3):785-93. PubMed ID: 24307208
    [Abstract] [Full Text] [Related]

  • 14. Murine thymic selection quantified using a unique method to capture deleted T cells.
    Stritesky GL, Xing Y, Erickson JR, Kalekar LA, Wang X, Mueller DL, Jameson SC, Hogquist KA.
    Proc Natl Acad Sci U S A; 2013 Mar 19; 110(12):4679-84. PubMed ID: 23487759
    [Abstract] [Full Text] [Related]

  • 15. Puma cooperates with Bim, the rate-limiting BH3-only protein in cell death during lymphocyte development, in apoptosis induction.
    Erlacher M, Labi V, Manzl C, Böck G, Tzankov A, Häcker G, Michalak E, Strasser A, Villunger A.
    J Exp Med; 2006 Dec 25; 203(13):2939-51. PubMed ID: 17178918
    [Abstract] [Full Text] [Related]

  • 16. BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes.
    Bouillet P, Purton JF, Godfrey DI, Zhang LC, Coultas L, Puthalakath H, Pellegrini M, Cory S, Adams JM, Strasser A.
    Nature; 2002 Feb 21; 415(6874):922-6. PubMed ID: 11859372
    [Abstract] [Full Text] [Related]

  • 17. Adenosine A2A receptor-mediated cell death of mouse thymocytes involves adenylate cyclase and Bim and is negatively regulated by Nur77.
    Kiss I, Oskolás H, Tóth R, Bouillet P, Tóth K, Fülöp A, Scholtz B, Ledent C, Fésüs L, Szondy Z.
    Eur J Immunol; 2006 Jun 21; 36(6):1559-71. PubMed ID: 16673448
    [Abstract] [Full Text] [Related]

  • 18. Regulation of Bim by TCR signals in CD4/CD8 double-positive thymocytes.
    Bunin A, Khwaja FW, Kersh GJ.
    J Immunol; 2005 Aug 01; 175(3):1532-9. PubMed ID: 16034091
    [Abstract] [Full Text] [Related]

  • 19. c-Cbl promotes T cell receptor-induced thymocyte apoptosis by activating the phosphatidylinositol 3-kinase/Akt pathway.
    Thien CB, Dagger SA, Steer JH, Koentgen F, Jansen ES, Scott CL, Langdon WY.
    J Biol Chem; 2010 Apr 02; 285(14):10969-81. PubMed ID: 20133944
    [Abstract] [Full Text] [Related]

  • 20. Cutting Edge: Bim is required for superantigen-mediated B cell death.
    Goodyear CS, Corr M, Sugiyama F, Boyle DL, Silverman GJ.
    J Immunol; 2007 Mar 01; 178(5):2636-40. PubMed ID: 17312102
    [Abstract] [Full Text] [Related]

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