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Journal Abstract Search

246 related items for PubMed ID: 25695315

  • 21. Estradiol dimer inhibits tubulin polymerization and microtubule dynamics.
    Jurášek M, Černohorská M, Řehulka J, Spiwok V, Sulimenko T, Dráberová E, Darmostuk M, Gurská S, Frydrych I, Buriánová R, Ruml T, Hajdúch M, Bartůněk P, Dráber P, Džubák P, Drašar PB, Sedlák D.
    J Steroid Biochem Mol Biol; 2018 Oct; 183():68-79. PubMed ID: 29803726
    [Abstract] [Full Text] [Related]

  • 22. Synthesis and biological evaluation of 1-phenyl-1,2,3,4-dihydroisoquinoline compounds as tubulin polymerization inhibitors.
    Zheng CH, Chen J, Liu J, Zhou XT, Liu N, Shi D, Huang JJ, Lv JG, Zhu J, Zhou YJ.
    Arch Pharm (Weinheim); 2012 Jun; 345(6):454-62. PubMed ID: 22415658
    [Abstract] [Full Text] [Related]

  • 23. Imidazoles and benzimidazoles as tubulin-modulators for anti-cancer therapy.
    Torres FC, García-Rubiño ME, Lozano-López C, Kawano DF, Eifler-Lima VL, von Poser GL, Campos JM.
    Curr Med Chem; 2015 Jun; 22(11):1312-23. PubMed ID: 25620093
    [Abstract] [Full Text] [Related]

  • 24. Structure-Based Design and Synthesis of N-Substituted 3-Amino-β-Carboline Derivatives as Potent αβ-Tubulin Degradation Agents.
    Li Y, Liu Y, Zhu Z, Yan W, Zhang C, Yang Z, Bai P, Tang M, Shi M, He W, Fu S, Liu J, Han K, Li J, Xie L, Ye H, Yang J, Chen L.
    J Med Chem; 2022 Feb 10; 65(3):2675-2693. PubMed ID: 35084853
    [Abstract] [Full Text] [Related]

  • 25. Design, synthesis and structure-activity relationship of 3,6-diaryl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines as novel tubulin inhibitors.
    Xu Q, Bao K, Sun M, Xu J, Wang Y, Tian H, Zuo D, Guan Q, Wu Y, Zhang W.
    Sci Rep; 2017 Sep 20; 7(1):11997. PubMed ID: 28931885
    [Abstract] [Full Text] [Related]

  • 26. The γ-tubulin-specific inhibitor gatastatin reveals temporal requirements of microtubule nucleation during the cell cycle.
    Chinen T, Liu P, Shioda S, Pagel J, Cerikan B, Lin TC, Gruss O, Hayashi Y, Takeno H, Shima T, Okada Y, Hayakawa I, Hayashi Y, Kigoshi H, Usui T, Schiebel E.
    Nat Commun; 2015 Oct 27; 6():8722. PubMed ID: 26503935
    [Abstract] [Full Text] [Related]

  • 27. Synthesis, antiproliferative activity and molecular docking of thiocolchicine urethanes.
    Majcher U, Urbaniak A, Maj E, Moshari M, Delgado M, Wietrzyk J, Bartl F, Chambers TC, Tuszynski JA, Huczyński A.
    Bioorg Chem; 2018 Dec 27; 81():553-566. PubMed ID: 30248507
    [Abstract] [Full Text] [Related]

  • 28. Binding of dihydroxynaphthyl aryl ketones to tubulin colchicine site inhibits microtubule assembly.
    Gutierrez E, Benites J, Valderrama JA, Calderon PB, Verrax J, Nova E, Villanelo F, Maturana D, Escobar C, Lagos R, Monasterio O.
    Biochem Biophys Res Commun; 2015 Oct 23; 466(3):418-25. PubMed ID: 26365353
    [Abstract] [Full Text] [Related]

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  • 30. Design, synthesis, and biological evaluation of novel combretastatin A-4 thio derivatives as microtubule targeting agents.
    Stefański T, Mikstacka R, Kurczab R, Dutkiewicz Z, Kucińska M, Murias M, Zielińska-Przyjemska M, Cichocki M, Teubert A, Kaczmarek M, Hogendorf A, Sobiak S.
    Eur J Med Chem; 2018 Jan 20; 144():797-816. PubMed ID: 29291446
    [Abstract] [Full Text] [Related]

  • 31. Design, Synthesis, and Evaluation of in Vitro and in Vivo Anticancer Activity of 4-Substituted Coumarins: A Novel Class of Potent Tubulin Polymerization Inhibitors.
    Cao D, Liu Y, Yan W, Wang C, Bai P, Wang T, Tang M, Wang X, Yang Z, Ma B, Ma L, Lei L, Wang F, Xu B, Zhou Y, Yang T, Chen L.
    J Med Chem; 2016 Jun 23; 59(12):5721-39. PubMed ID: 27213819
    [Abstract] [Full Text] [Related]

  • 32. Synthesis and Biochemical Evaluation of 3-Phenoxy-1,4-diarylazetidin-2-ones as Tubulin-Targeting Antitumor Agents.
    Greene TF, Wang S, Greene LM, Nathwani SM, Pollock JK, Malebari AM, McCabe T, Twamley B, O'Boyle NM, Zisterer DM, Meegan MJ.
    J Med Chem; 2016 Jan 14; 59(1):90-113. PubMed ID: 26680364
    [Abstract] [Full Text] [Related]

  • 33. Synthesis and biological evaluation of novel pyranochalcone derivatives as a new class of microtubule stabilizing agents.
    Cao D, Han X, Wang G, Yang Z, Peng F, Ma L, Zhang R, Ye H, Tang M, Wu W, Lei K, Wen J, Chen J, Qiu J, Liang X, Ran Y, Sang Y, Xiang M, Peng A, Chen L.
    Eur J Med Chem; 2013 Apr 14; 62():579-89. PubMed ID: 23425970
    [Abstract] [Full Text] [Related]

  • 34. Novel quinolone chalcones targeting colchicine-binding pocket kill multidrug-resistant cancer cells by inhibiting tubulin activity and MRP1 function.
    Lindamulage IK, Vu HY, Karthikeyan C, Knockleby J, Lee YF, Trivedi P, Lee H.
    Sci Rep; 2017 Aug 31; 7(1):10298. PubMed ID: 28860494
    [Abstract] [Full Text] [Related]

  • 35. Design, synthesis, and biological evaluation of (E)-N-aryl-2-arylethenesulfonamide analogues as potent and orally bioavailable microtubule-targeted anticancer agents.
    Reddy MV, Mallireddigari MR, Pallela VR, Cosenza SC, Billa VK, Akula B, Subbaiah DR, Bharathi EV, Padgaonkar A, Lv H, Gallo JM, Reddy EP.
    J Med Chem; 2013 Jul 11; 56(13):5562-86. PubMed ID: 23750455
    [Abstract] [Full Text] [Related]

  • 36. New benzimidazole-2-urea derivates as tubulin inhibitors.
    Wang W, Kong D, Cheng H, Tan L, Zhang Z, Zhuang X, Long H, Zhou Y, Xu Y, Yang X, Ding K.
    Bioorg Med Chem Lett; 2014 Sep 01; 24(17):4250-3. PubMed ID: 25091926
    [Abstract] [Full Text] [Related]

  • 37. Synthesis, structure-activity relationships and biological evaluation of 7-phenyl-pyrroloquinolinone 3-amide derivatives as potent antimitotic agents.
    Carta D, Bortolozzi R, Sturlese M, Salmaso V, Hamel E, Basso G, Calderan L, Quintieri L, Moro S, Viola G, Ferlin MG.
    Eur J Med Chem; 2017 Feb 15; 127():643-660. PubMed ID: 27823884
    [Abstract] [Full Text] [Related]

  • 38. BZML, a novel colchicine binding site inhibitor, overcomes multidrug resistance in A549/Taxol cells by inhibiting P-gp function and inducing mitotic catastrophe.
    Bai Z, Gao M, Zhang H, Guan Q, Xu J, Li Y, Qi H, Li Z, Zuo D, Zhang W, Wu Y.
    Cancer Lett; 2017 Aug 28; 402():81-92. PubMed ID: 28576750
    [Abstract] [Full Text] [Related]

  • 39. 3-substituted 2-phenylimidazo[2,1-b]benzothiazoles: synthesis, anticancer activity, and inhibition of tubulin polymerization.
    Kamal A, Sultana F, Ramaiah MJ, Srikanth YV, Viswanath A, Kishor C, Sharma P, Pushpavalli SN, Addlagatta A, Pal-Bhadra M.
    ChemMedChem; 2012 Feb 06; 7(2):292-300. PubMed ID: 22241597
    [Abstract] [Full Text] [Related]

  • 40. Synthesis and evaluation of new 2-chloro-4-aminopyrimidine and 2,6-dimethyl-4-aminopyrimidine derivatives as tubulin polymerization inhibitors.
    Xu S, An B, Li Y, Luo X, Li X, Jia X.
    Bioorg Med Chem Lett; 2018 Jun 01; 28(10):1769-1775. PubMed ID: 29673981
    [Abstract] [Full Text] [Related]

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