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Journal Abstract Search

127 related items for PubMed ID: 2569942

  • 1. Syntheses of the metabolites of 1-(2-ethoxyethyl)-2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-1H benzimidazole difumarate (KG-2413) and related compounds.
    Iemura R, Hori M, Ohtaka H.
    Chem Pharm Bull (Tokyo); 1989 Apr; 37(4):962-6. PubMed ID: 2569942
    [Abstract] [Full Text] [Related]

  • 2. Synthesis and structure-activity relationships of a new series of benzimidazoles as H1-antihistaminic agents.
    Cuberes MR, Contijoch M, Calvet C, Alegre J, Quintana JR, Frigola J.
    Chem Pharm Bull (Tokyo); 1997 Aug; 45(8):1287-92. PubMed ID: 9301027
    [Abstract] [Full Text] [Related]

  • 3. Bioisosteric transformation of H1-antihistaminic benzimidazole derivatives.
    Iemura R, Hori M, Saito T, Ohtaka H.
    Chem Pharm Bull (Tokyo); 1989 Oct; 37(10):2723-6. PubMed ID: 2575462
    [Abstract] [Full Text] [Related]

  • 4. Synthesis of 2-(4-substituted-1-piperazinyl)benzimidazoles as H1-antihistaminic agents.
    Iemura R, Kawashima T, Fukuda T, Ito K, Tsukamoto G.
    J Med Chem; 1986 Jul; 29(7):1178-83. PubMed ID: 2879912
    [Abstract] [Full Text] [Related]

  • 5. [Cross-reactivities of active metabolites in the radioreceptor assay of an antiallergic agent, 1-(2-ethoxyethyl)-2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)- 1H-benzimidazole difumarate (KG-2413)].
    Hamada T, Kawashima T, Awata N.
    Yakugaku Zasshi; 1989 Jul; 109(7):474-9. PubMed ID: 2573721
    [Abstract] [Full Text] [Related]

  • 6. Synthesis of benzimidazole derivatives with potential antihistaminic activity.
    Rida SM, el-Dine SA, Labouta IM.
    Pharmazie; 1977 Oct; 32(10):577-9. PubMed ID: 24226
    [No Abstract] [Full Text] [Related]

  • 7. [Selective and sensitive determination of an antiallergic agent, emedastine difumarate (KG-2413), in human plasma by the radioreceptor assay combined with a high-performance liquid chromatography].
    Hamada T, Kawashima T, Awata N.
    Yakugaku Zasshi; 1989 Oct; 109(10):749-54. PubMed ID: 2576060
    [Abstract] [Full Text] [Related]

  • 8. Effect of 1-(2-ethoxyethyl)-2-(4-methyl-1-homopiperazinyl)-benzimida zole difumarate (KB-2413), a new antiallergic, on chemical mediators.
    Fukuda T, Morimoto Y, Iemura R, Kawashima T, Tsukamoto G, Ito K.
    Arzneimittelforschung; 1984 Oct; 34(7):801-5. PubMed ID: 6149754
    [Abstract] [Full Text] [Related]

  • 9. Pharmacokinetics of an antiallergic agent, 1-(2-ethoxyethyl)-2-(hexahydro-4-methyl-1H-1, 4-diazepin-1-yl)-1H-benzimidazole difumarate (KG-2413) after oral administration: interspecies differences in rats, guinea pigs and dogs.
    Sakai T, Hamada T, Awata N, Watanabe J.
    J Pharmacobiodyn; 1989 Sep; 12(9):530-6. PubMed ID: 2575663
    [Abstract] [Full Text] [Related]

  • 10. [Identification of the metabolites of an antiallergic agent, 1-(2-ethoxyethyl)-2-(hexahydro-4-methyl-1H-1,4-diazepine-1-yl)-1H- benzimidazole difumarate (KG-2413), in rats].
    Awata N, Takahashi H, Noumi K, Sakai T, Hamada T.
    Yakugaku Zasshi; 1989 May; 109(5):318-28. PubMed ID: 2576283
    [Abstract] [Full Text] [Related]

  • 11. [Synthesis of hexahydro-1,4-diazepine derivatives with potential pharmacological effects. IV. Synthesis and studies on the antihistaminic activity of hexahydro-1,4-diazepine derivatives containing ether groups].
    Guryn R, Kotełko A, Majchrzak M, Szadowska A, Wejman I.
    Acta Pol Pharm; 1980 May; 37(1):53-8. PubMed ID: 6104893
    [No Abstract] [Full Text] [Related]

  • 12. Quantitative structure-activity relationships of H1-antihistaminic benzimidazole derivatives.
    Iemura R, Ohtaka H.
    Chem Pharm Bull (Tokyo); 1989 Apr; 37(4):967-72. PubMed ID: 2569943
    [Abstract] [Full Text] [Related]

  • 13. Radioreceptor assay for a new antiallergic agent, 1-(2-ethoxyethyl)-2-(4-methyl-1-homopiperazinyl)benzimidazole difumarate (KB-2413), in plasma.
    Hamada T, Kadowaki M, Awata N.
    Chem Pharm Bull (Tokyo); 1987 Aug; 35(8):3329-35. PubMed ID: 2892589
    [No Abstract] [Full Text] [Related]

  • 14. Synthesis of new 2-substituted-[1,3,4]-oxadiazino-[6,5-b]-indoles with H1-antihistaminic, antimuscarinic and antimicrobial activity [corrected].
    Ajitha M, Rajnarayana K, Sarangapani M.
    Pharmazie; 2002 Dec; 57(12):796-9. PubMed ID: 12561237
    [Abstract] [Full Text] [Related]

  • 15. Non-imidazole histamine H3 ligands. Part I. Synthesis of 2-(1-piperazinyl)- and 2-(hexahydro-1H-1,4-diazepin-1-yl)benzothiazole derivatives as H3-antagonists with H1 blocking activities.
    Walczyński K, Guryn R, Zuiderveld OP, Timmerman H.
    Farmaco; 1999 Oct 30; 54(10):684-94. PubMed ID: 10575738
    [Abstract] [Full Text] [Related]

  • 16. Interspecies differences in pharmacokinetics of an antiallergic agent, 1-(2-ethoxyethyl)-2-(hexahydro-4-methyl-1,4-diazepin-1-yl) benzimidazole difumarate (KG-2413) after intravenous administration to rats, guinea pigs and dogs.
    Sakai T, Hamada T, Awata N, Watanabe J.
    Chem Pharm Bull (Tokyo); 1989 Mar 30; 37(3):753-6. PubMed ID: 2568892
    [Abstract] [Full Text] [Related]

  • 17. General pharmacology of 1-(2-ethoxyethyl)-2-(4-methyl-1-homopiperazinyl)benzimidazole difumarate. 2nd communication: Effects on the circulation and the other systems.
    Saito T, Fukuda T, Tajima S, Sukamoto T, Yamashita A, Kanazawa T, Morimoto Y, Shimohara K, Nishimura N, Yokota K.
    Arzneimittelforschung; 1988 Feb 30; 38(2):267-72. PubMed ID: 2897196
    [Abstract] [Full Text] [Related]

  • 18. [Histamine analogs. 28. 2-(Aryloxyalkyl)- and 3(aminoalkyl)-histamines].
    Steffens R, Schunack W.
    Arch Pharm (Weinheim); 1987 Feb 30; 320(2):135-40. PubMed ID: 2883957
    [No Abstract] [Full Text] [Related]

  • 19. [4-[Benzyl-(2-dimethylaminoethyl)amino]pyrimidine compounds with selective antagonistic activity against H1-histamine receptors].
    Mossini F, Maggiali C, Morini G, Impicciatore M, Morini G, Molina E.
    Farmaco Sci; 1984 Mar 30; 39(3):189-99. PubMed ID: 6143687
    [Abstract] [Full Text] [Related]

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