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Journal Abstract Search

587 related items for PubMed ID: 25707573

  • 1. The Histone Deacetylase Sirtuin 1 Is Reduced in Systemic Sclerosis and Abrogates Fibrotic Responses by Targeting Transforming Growth Factor β Signaling.
    Wei J, Ghosh AK, Chu H, Fang F, Hinchcliff ME, Wang J, Marangoni RG, Varga J.
    Arthritis Rheumatol; 2015 May; 67(5):1323-34. PubMed ID: 25707573
    [Abstract] [Full Text] [Related]

  • 2. Sirt1 regulates canonical TGF-β signalling to control fibroblast activation and tissue fibrosis.
    Zerr P, Palumbo-Zerr K, Huang J, Tomcik M, Sumova B, Distler O, Schett G, Distler JH.
    Ann Rheum Dis; 2016 Jan; 75(1):226-33. PubMed ID: 25180292
    [Abstract] [Full Text] [Related]

  • 3. Fibroblast expression of the coactivator p300 governs the intensity of profibrotic response to transforming growth factor beta.
    Bhattacharyya S, Ghosh AK, Pannu J, Mori Y, Takagawa S, Chen G, Trojanowska M, Gilliam AC, Varga J.
    Arthritis Rheum; 2005 Apr; 52(4):1248-58. PubMed ID: 15818659
    [Abstract] [Full Text] [Related]

  • 4. Inhibition of activator protein 1 signaling abrogates transforming growth factor β-mediated activation of fibroblasts and prevents experimental fibrosis.
    Avouac J, Palumbo K, Tomcik M, Zerr P, Dees C, Horn A, Maurer B, Akhmetshina A, Beyer C, Sadowski A, Schneider H, Shiozawa S, Distler O, Schett G, Allanore Y, Distler JH.
    Arthritis Rheum; 2012 May; 64(5):1642-52. PubMed ID: 22139817
    [Abstract] [Full Text] [Related]

  • 5. p300 is elevated in systemic sclerosis and its expression is positively regulated by TGF-β: epigenetic feed-forward amplification of fibrosis.
    Ghosh AK, Bhattacharyya S, Lafyatis R, Farina G, Yu J, Thimmapaya B, Wei J, Varga J.
    J Invest Dermatol; 2013 May; 133(5):1302-10. PubMed ID: 23303459
    [Abstract] [Full Text] [Related]

  • 6. Sirt1 ameliorates systemic sclerosis by targeting the mTOR pathway.
    Zhu X, Chu H, Jiang S, Liu Q, Liu L, Xue Y, Zheng S, Wan W, Qiu J, Wang J, Zou H.
    J Dermatol Sci; 2017 Aug; 87(2):149-158. PubMed ID: 28532580
    [Abstract] [Full Text] [Related]

  • 7. The nuclear receptor constitutive androstane receptor/NR1I3 enhances the profibrotic effects of transforming growth factor β and contributes to the development of experimental dermal fibrosis.
    Avouac J, Palumbo-Zerr K, Ruzehaji N, Tomcik M, Zerr P, Dees C, Distler A, Beyer C, Schneider H, Distler O, Schett G, Allanore Y, Distler JH.
    Arthritis Rheumatol; 2014 Nov; 66(11):3140-50. PubMed ID: 25155144
    [Abstract] [Full Text] [Related]

  • 8. Tribbles homologue 3 stimulates canonical TGF-β signalling to regulate fibroblast activation and tissue fibrosis.
    Tomcik M, Palumbo-Zerr K, Zerr P, Sumova B, Avouac J, Dees C, Distler A, Becvar R, Distler O, Schett G, Senolt L, Distler JH.
    Ann Rheum Dis; 2016 Mar; 75(3):609-16. PubMed ID: 25603829
    [Abstract] [Full Text] [Related]

  • 9. The transcription factor Fra-2 regulates the production of extracellular matrix in systemic sclerosis.
    Reich N, Maurer B, Akhmetshina A, Venalis P, Dees C, Zerr P, Palumbo K, Zwerina J, Nevskaya T, Gay S, Distler O, Schett G, Distler JH.
    Arthritis Rheum; 2010 Jan; 62(1):280-90. PubMed ID: 20039427
    [Abstract] [Full Text] [Related]

  • 10. Selective inhibition of activin receptor-like kinase 5 signaling blocks profibrotic transforming growth factor beta responses in skin fibroblasts.
    Mori Y, Ishida W, Bhattacharyya S, Li Y, Platanias LC, Varga J.
    Arthritis Rheum; 2004 Dec; 50(12):4008-21. PubMed ID: 15593186
    [Abstract] [Full Text] [Related]

  • 11. Connective tissue growth factor causes persistent proalpha2(I) collagen gene expression induced by transforming growth factor-beta in a mouse fibrosis model.
    Chujo S, Shirasaki F, Kawara S, Inagaki Y, Kinbara T, Inaoki M, Takigawa M, Takehara K.
    J Cell Physiol; 2005 May; 203(2):447-56. PubMed ID: 15605379
    [Abstract] [Full Text] [Related]

  • 12. Vitamin D receptor regulates TGF-β signalling in systemic sclerosis.
    Zerr P, Vollath S, Palumbo-Zerr K, Tomcik M, Huang J, Distler A, Beyer C, Dees C, Gela K, Distler O, Schett G, Distler JH.
    Ann Rheum Dis; 2015 Mar; 74(3):e20. PubMed ID: 24448349
    [Abstract] [Full Text] [Related]

  • 13. The transcription factor GLI2 as a downstream mediator of transforming growth factor-β-induced fibroblast activation in SSc.
    Liang R, Šumová B, Cordazzo C, Mallano T, Zhang Y, Wohlfahrt T, Dees C, Ramming A, Krasowska D, Michalska-Jakubus M, Distler O, Schett G, Šenolt L, Distler JH.
    Ann Rheum Dis; 2017 Apr; 76(4):756-764. PubMed ID: 27793816
    [Abstract] [Full Text] [Related]

  • 14. Heat shock protein 90 (Hsp90) inhibition targets canonical TGF-β signalling to prevent fibrosis.
    Tomcik M, Zerr P, Pitkowski J, Palumbo-Zerr K, Avouac J, Distler O, Becvar R, Senolt L, Schett G, Distler JH.
    Ann Rheum Dis; 2014 Jun; 73(6):1215-22. PubMed ID: 23661493
    [Abstract] [Full Text] [Related]

  • 15. Disruption of transforming growth factor beta signaling and profibrotic responses in normal skin fibroblasts by peroxisome proliferator-activated receptor gamma.
    Ghosh AK, Bhattacharyya S, Lakos G, Chen SJ, Mori Y, Varga J.
    Arthritis Rheum; 2004 Apr; 50(4):1305-18. PubMed ID: 15077315
    [Abstract] [Full Text] [Related]

  • 16. Inhibition of casein kinase II reduces TGFβ induced fibroblast activation and ameliorates experimental fibrosis.
    Zhang Y, Dees C, Beyer C, Lin NY, Distler A, Zerr P, Palumbo K, Susok L, Kreuter A, Distler O, Schett G, Distler JH.
    Ann Rheum Dis; 2015 May; 74(5):936-43. PubMed ID: 24431397
    [Abstract] [Full Text] [Related]

  • 17. A novel inhibitor of Smad-dependent transcriptional activation suppresses tissue fibrosis in mouse models of systemic sclerosis.
    Hasegawa M, Matsushita Y, Horikawa M, Higashi K, Tomigahara Y, Kaneko H, Shirasaki F, Fujimoto M, Takehara K, Sato S.
    Arthritis Rheum; 2009 Nov; 60(11):3465-75. PubMed ID: 19877032
    [Abstract] [Full Text] [Related]

  • 18. Scleroderma keratinocytes promote fibroblast activation independent of transforming growth factor beta.
    McCoy SS, Reed TJ, Berthier CC, Tsou PS, Liu J, Gudjonsson JE, Khanna D, Kahlenberg JM.
    Rheumatology (Oxford); 2017 Nov 01; 56(11):1970-1981. PubMed ID: 28968684
    [Abstract] [Full Text] [Related]

  • 19. Postnatal induction of transforming growth factor beta signaling in fibroblasts of mice recapitulates clinical, histologic, and biochemical features of scleroderma.
    Sonnylal S, Denton CP, Zheng B, Keene DR, He R, Adams HP, Vanpelt CS, Geng YJ, Deng JM, Behringer RR, de Crombrugghe B.
    Arthritis Rheum; 2007 Jan 01; 56(1):334-44. PubMed ID: 17195237
    [Abstract] [Full Text] [Related]

  • 20. Angiotensin II in the lesional skin of systemic sclerosis patients contributes to tissue fibrosis via angiotensin II type 1 receptors.
    Kawaguchi Y, Takagi K, Hara M, Fukasawa C, Sugiura T, Nishimagi E, Harigai M, Kamatani N.
    Arthritis Rheum; 2004 Jan 01; 50(1):216-26. PubMed ID: 14730619
    [Abstract] [Full Text] [Related]

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