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Journal Abstract Search

189 related items for PubMed ID: 25715168

  • 1. Interferon-β Mediates Signaling Pathways Uniquely Regulated in Hepatic Stellate Cells and Attenuates the Progression of Hepatic Fibrosis in a Dietary Mouse Model.
    Shimozono R, Nishimura K, Akiyama H, Funamoto S, Izawa A, Sai T, Kunita K, Kainoh M, Suzuki T, Kawada N.
    J Interferon Cytokine Res; 2015 Jun; 35(6):464-73. PubMed ID: 25715168
    [Abstract] [Full Text] [Related]

  • 2. IFN-γ deficiency attenuates hepatic inflammation and fibrosis in a steatohepatitis model induced by a methionine- and choline-deficient high-fat diet.
    Luo XY, Takahara T, Kawai K, Fujino M, Sugiyama T, Tsuneyama K, Tsukada K, Nakae S, Zhong L, Li XK.
    Am J Physiol Gastrointest Liver Physiol; 2013 Dec; 305(12):G891-9. PubMed ID: 24136786
    [Abstract] [Full Text] [Related]

  • 3. A high-cholesterol diet exacerbates liver fibrosis in mice via accumulation of free cholesterol in hepatic stellate cells.
    Teratani T, Tomita K, Suzuki T, Oshikawa T, Yokoyama H, Shimamura K, Tominaga S, Hiroi S, Irie R, Okada Y, Kurihara C, Ebinuma H, Saito H, Hokari R, Sugiyama K, Kanai T, Miura S, Hibi T.
    Gastroenterology; 2012 Jan; 142(1):152-164.e10. PubMed ID: 21995947
    [Abstract] [Full Text] [Related]

  • 4. Cross talk between toll-like receptor-4 signaling and angiotensin-II in liver fibrosis development in the rat model of non-alcoholic steatohepatitis.
    Shirai Y, Yoshiji H, Noguchi R, Kaji K, Aihara Y, Douhara A, Moriya K, Namisaki T, Kawaratani H, Fukui H.
    J Gastroenterol Hepatol; 2013 Apr; 28(4):723-30. PubMed ID: 23301938
    [Abstract] [Full Text] [Related]

  • 5. Free cholesterol accumulation in hepatic stellate cells: mechanism of liver fibrosis aggravation in nonalcoholic steatohepatitis in mice.
    Tomita K, Teratani T, Suzuki T, Shimizu M, Sato H, Narimatsu K, Okada Y, Kurihara C, Irie R, Yokoyama H, Shimamura K, Usui S, Ebinuma H, Saito H, Watanabe C, Komoto S, Kawaguchi A, Nagao S, Sugiyama K, Hokari R, Kanai T, Miura S, Hibi T.
    Hepatology; 2014 Jan; 59(1):154-69. PubMed ID: 23832448
    [Abstract] [Full Text] [Related]

  • 6. Acyl-CoA:cholesterol acyltransferase 1 mediates liver fibrosis by regulating free cholesterol accumulation in hepatic stellate cells.
    Tomita K, Teratani T, Suzuki T, Shimizu M, Sato H, Narimatsu K, Usui S, Furuhashi H, Kimura A, Nishiyama K, Maejima T, Okada Y, Kurihara C, Shimamura K, Ebinuma H, Saito H, Yokoyama H, Watanabe C, Komoto S, Nagao S, Sugiyama K, Aosasa S, Hatsuse K, Yamamoto J, Hibi T, Miura S, Hokari R, Kanai T.
    J Hepatol; 2014 Jul; 61(1):98-106. PubMed ID: 24657401
    [Abstract] [Full Text] [Related]

  • 7. TLR4‑dependent signaling pathway modulation: A novel mechanism by which pioglitazone protects against nutritional fibrotic steatohepatitis in mice.
    Du J, Niu X, Wang R, Zhao S, Kong L, Zhang Y, Nan Y.
    Mol Med Rep; 2016 Mar; 13(3):2159-66. PubMed ID: 26781175
    [Abstract] [Full Text] [Related]

  • 8. Pan-caspase inhibitor VX-166 reduces fibrosis in an animal model of nonalcoholic steatohepatitis.
    Witek RP, Stone WC, Karaca FG, Syn WK, Pereira TA, Agboola KM, Omenetti A, Jung Y, Teaberry V, Choi SS, Guy CD, Pollard J, Charlton P, Diehl AM.
    Hepatology; 2009 Nov; 50(5):1421-30. PubMed ID: 19676126
    [Abstract] [Full Text] [Related]

  • 9. Metformin ameliorates activation of hepatic stellate cells and hepatic fibrosis by succinate and GPR91 inhibition.
    Nguyen G, Park SY, Le CT, Park WS, Choi DH, Cho EH.
    Biochem Biophys Res Commun; 2018 Jan 22; 495(4):2649-2656. PubMed ID: 29278707
    [Abstract] [Full Text] [Related]

  • 10. Rho/Rho kinase is a key enzyme system involved in the angiotensin II signaling pathway of liver fibrosis and steatosis.
    Kitamura K, Tada S, Nakamoto N, Toda K, Horikawa H, Kurita S, Tsunematsu S, Kumagai N, Ishii H, Saito H, Hibi T.
    J Gastroenterol Hepatol; 2007 Nov 22; 22(11):2022-33. PubMed ID: 17914985
    [Abstract] [Full Text] [Related]

  • 11. Sparstolonin B (SsnB) attenuates liver fibrosis via a parallel conjugate pathway involving P53-P21 axis, TGF-beta signaling and focal adhesion that is TLR4 dependent.
    Dattaroy D, Seth RK, Sarkar S, Kimono D, Albadrani M, Chandrashekaran V, Hasson FA, Singh UP, Fan D, Nagarkatti M, Nagarkatti P, Diehl AM, Chatterjee S.
    Eur J Pharmacol; 2018 Dec 15; 841():33-48. PubMed ID: 30194936
    [Abstract] [Full Text] [Related]

  • 12. Reduction of endotoxin attenuates liver fibrosis through suppression of hepatic stellate cell activation and remission of intestinal permeability in a rat non-alcoholic steatohepatitis model.
    Douhara A, Moriya K, Yoshiji H, Noguchi R, Namisaki T, Kitade M, Kaji K, Aihara Y, Nishimura N, Takeda K, Okura Y, Kawaratani H, Fukui H.
    Mol Med Rep; 2015 Mar 15; 11(3):1693-700. PubMed ID: 25421042
    [Abstract] [Full Text] [Related]

  • 13. The activation of TLR4-MyD88 signaling promotes hepatic dysfunction and fibrotic changes in SD rats resulting from prolonged exposure to sodium arsenite.
    Song Q, Jin Y, He R, Fan L, Tu C, Chen X, Wang D.
    Int Immunopharmacol; 2024 Oct 25; 140():112823. PubMed ID: 39083929
    [Abstract] [Full Text] [Related]

  • 14. Peptide-modified albumin carrier explored as a novel strategy for a cell-specific delivery of interferon gamma to treat liver fibrosis.
    Bansal R, Prakash J, de Ruijter M, Beljaars L, Poelstra K.
    Mol Pharm; 2011 Oct 03; 8(5):1899-909. PubMed ID: 21800888
    [Abstract] [Full Text] [Related]

  • 15. Evaluation of NV556, a Novel Cyclophilin Inhibitor, as a Potential Antifibrotic Compound for Liver Fibrosis.
    Simón Serrano S, Grönberg A, Longato L, Rombouts K, Kuo J, Gregory M, Moss S, Elmér E, Mazza G, Gallay P, Pinzani M, Hansson MJ, Massoumi R.
    Cells; 2019 Nov 08; 8(11):. PubMed ID: 31717385
    [Abstract] [Full Text] [Related]

  • 16. Functional linkage of cirrhosis-predictive single nucleotide polymorphisms of Toll-like receptor 4 to hepatic stellate cell responses.
    Guo J, Loke J, Zheng F, Hong F, Yea S, Fukata M, Tarocchi M, Abar OT, Huang H, Sninsky JJ, Friedman SL.
    Hepatology; 2009 Mar 08; 49(3):960-8. PubMed ID: 19085953
    [Abstract] [Full Text] [Related]

  • 17. Toll-like receptor-4 signalling in the progression of non-alcoholic fatty liver disease induced by high-fat and high-fructose diet in mice.
    Liu J, Zhuang ZJ, Bian DX, Ma XJ, Xun YH, Yang WJ, Luo Y, Liu YL, Jia L, Wang Y, Zhu ML, Ye DW, Zhou G, Lou GQ, Shi JP.
    Clin Exp Pharmacol Physiol; 2014 Jul 08; 41(7):482-8. PubMed ID: 24739055
    [Abstract] [Full Text] [Related]

  • 18. Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway.
    Yamamoto M, Sato S, Hemmi H, Hoshino K, Kaisho T, Sanjo H, Takeuchi O, Sugiyama M, Okabe M, Takeda K, Akira S.
    Science; 2003 Aug 01; 301(5633):640-3. PubMed ID: 12855817
    [Abstract] [Full Text] [Related]

  • 19. HGF and direct mesenchymal stem cells contact synergize to inhibit hepatic stellate cells activation through TLR4/NF-kB pathway.
    Wang PP, Xie DY, Liang XJ, Peng L, Zhang GL, Ye YN, Xie C, Gao ZL.
    PLoS One; 2012 Aug 01; 7(8):e43408. PubMed ID: 22927965
    [Abstract] [Full Text] [Related]

  • 20. Melatonin modulates TLR4-mediated inflammatory genes through MyD88- and TRIF-dependent signaling pathways in lipopolysaccharide-stimulated RAW264.7 cells.
    Xia MZ, Liang YL, Wang H, Chen X, Huang YY, Zhang ZH, Chen YH, Zhang C, Zhao M, Xu DX, Song LH.
    J Pineal Res; 2012 Nov 01; 53(4):325-34. PubMed ID: 22537289
    [Abstract] [Full Text] [Related]

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