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Journal Abstract Search

233 related items for PubMed ID: 25716680

  • 1. Usp28 counteracts Fbw7 in intestinal homeostasis and cancer.
    Diefenbacher ME, Chakraborty A, Blake SM, Mitter R, Popov N, Eilers M, Behrens A.
    Cancer Res; 2015 Apr 01; 75(7):1181-6. PubMed ID: 25716680
    [Abstract] [Full Text] [Related]

  • 2. Dual regulation of Fbw7 function and oncogenic transformation by Usp28.
    Schülein-Völk C, Wolf E, Zhu J, Xu W, Taranets L, Hellmann A, Jänicke LA, Diefenbacher ME, Behrens A, Eilers M, Popov N.
    Cell Rep; 2014 Nov 06; 9(3):1099-109. PubMed ID: 25437563
    [Abstract] [Full Text] [Related]

  • 3. F-box and WD repeat domain-containing 7 regulates intestinal cell lineage commitment and is a haploinsufficient tumor suppressor.
    Sancho R, Jandke A, Davis H, Diefenbacher ME, Tomlinson I, Behrens A.
    Gastroenterology; 2010 Sep 06; 139(3):929-41. PubMed ID: 20638938
    [Abstract] [Full Text] [Related]

  • 4. GSK-3β regulates cell growth, migration, and angiogenesis via Fbw7 and USP28-dependent degradation of HIF-1α.
    Flügel D, Görlach A, Kietzmann T.
    Blood; 2012 Feb 02; 119(5):1292-301. PubMed ID: 22144179
    [Abstract] [Full Text] [Related]

  • 5. Fbw7 and Usp28 regulate myc protein stability in response to DNA damage.
    Popov N, Herold S, Llamazares M, Schülein C, Eilers M.
    Cell Cycle; 2007 Oct 01; 6(19):2327-31. PubMed ID: 17873522
    [Abstract] [Full Text] [Related]

  • 6. The deubiquitinase USP28 controls intestinal homeostasis and promotes colorectal cancer.
    Diefenbacher ME, Popov N, Blake SM, Schülein-Völk C, Nye E, Spencer-Dene B, Jaenicke LA, Eilers M, Behrens A.
    J Clin Invest; 2014 Aug 01; 124(8):3407-18. PubMed ID: 24960159
    [Abstract] [Full Text] [Related]

  • 7. FBXW7 influences murine intestinal homeostasis and cancer, targeting Notch, Jun, and DEK for degradation.
    Babaei-Jadidi R, Li N, Saadeddin A, Spencer-Dene B, Jandke A, Muhammad B, Ibrahim EE, Muraleedharan R, Abuzinadah M, Davis H, Lewis A, Watson S, Behrens A, Tomlinson I, Nateri AS.
    J Exp Med; 2011 Feb 14; 208(2):295-312. PubMed ID: 21282377
    [Abstract] [Full Text] [Related]

  • 8. Adenovirus E1A inhibits SCF(Fbw7) ubiquitin ligase.
    Isobe T, Hattori T, Kitagawa K, Uchida C, Kotake Y, Kosugi I, Oda T, Kitagawa M.
    J Biol Chem; 2009 Oct 09; 284(41):27766-27779. PubMed ID: 19679664
    [Abstract] [Full Text] [Related]

  • 9. The F-box protein FBXL16 up-regulates the stability of C-MYC oncoprotein by antagonizing the activity of the F-box protein FBW7.
    Morel M, Shah KN, Long W.
    J Biol Chem; 2020 Jun 05; 295(23):7970-7980. PubMed ID: 32345600
    [Abstract] [Full Text] [Related]

  • 10. Ubiquitin Ligase, Fbw7, Targets CDX2 for Degradation via Two Phosphodegron Motifs in a GSK3β-Dependent Manner.
    Kumar Y, Shukla N, Thacker G, Kapoor I, Lochab S, Bhatt ML, Chattopadhyay N, Sanyal S, Trivedi AK.
    Mol Cancer Res; 2016 Nov 05; 14(11):1097-1109. PubMed ID: 27470268
    [Abstract] [Full Text] [Related]

  • 11. Regulation of GATA-binding protein 2 levels via ubiquitin-dependent degradation by Fbw7: involvement of cyclin B-cyclin-dependent kinase 1-mediated phosphorylation of THR176 in GATA-binding protein 2.
    Nakajima T, Kitagawa K, Ohhata T, Sakai S, Uchida C, Shibata K, Minegishi N, Yumimoto K, Nakayama KI, Masumoto K, Katou F, Niida H, Kitagawa M.
    J Biol Chem; 2015 Apr 17; 290(16):10368-81. PubMed ID: 25670854
    [Abstract] [Full Text] [Related]

  • 12. Isoform-specific SCF(Fbw7) ubiquitination mediates differential regulation of PGC-1α.
    Trausch-Azar JS, Abed M, Orian A, Schwartz AL.
    J Cell Physiol; 2015 Apr 17; 230(4):842-52. PubMed ID: 25204433
    [Abstract] [Full Text] [Related]

  • 13. Fbw7 repression by hes5 creates a feedback loop that modulates Notch-mediated intestinal and neural stem cell fate decisions.
    Sancho R, Blake SM, Tendeng C, Clurman BE, Lewis J, Behrens A.
    PLoS Biol; 2013 Apr 17; 11(6):e1001586. PubMed ID: 23776410
    [Abstract] [Full Text] [Related]

  • 14. Stringent Control of NFE2L3 (Nuclear Factor, Erythroid 2-Like 3; NRF3) Protein Degradation by FBW7 (F-box/WD Repeat-containing Protein 7) and Glycogen Synthase Kinase 3 (GSK3).
    Kannan MB, Dodard-Friedman I, Blank V.
    J Biol Chem; 2015 Oct 23; 290(43):26292-302. PubMed ID: 26306035
    [Abstract] [Full Text] [Related]

  • 15. The Fbw7/human CDC4 tumor suppressor targets proproliferative factor KLF5 for ubiquitination and degradation through multiple phosphodegron motifs.
    Liu N, Li H, Li S, Shen M, Xiao N, Chen Y, Wang Y, Wang W, Wang R, Wang Q, Sun J, Wang P.
    J Biol Chem; 2010 Jun 11; 285(24):18858-67. PubMed ID: 20388706
    [Abstract] [Full Text] [Related]

  • 16. SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction.
    Inuzuka H, Shaik S, Onoyama I, Gao D, Tseng A, Maser RS, Zhai B, Wan L, Gutierrez A, Lau AW, Xiao Y, Christie AL, Aster J, Settleman J, Gygi SP, Kung AL, Look T, Nakayama KI, DePinho RA, Wei W.
    Nature; 2011 Mar 03; 471(7336):104-9. PubMed ID: 21368833
    [Abstract] [Full Text] [Related]

  • 17. ERK kinase phosphorylates and destabilizes the tumor suppressor FBW7 in pancreatic cancer.
    Ji S, Qin Y, Shi S, Liu X, Hu H, Zhou H, Gao J, Zhang B, Xu W, Liu J, Liang D, Liu L, Liu C, Long J, Zhou H, Chiao PJ, Xu J, Ni Q, Gao D, Yu X.
    Cell Res; 2015 May 03; 25(5):561-73. PubMed ID: 25753158
    [Abstract] [Full Text] [Related]

  • 18. FBW7 regulates endothelial functions by targeting KLF2 for ubiquitination and degradation.
    Wang R, Wang Y, Liu N, Ren C, Jiang C, Zhang K, Yu S, Chen Y, Tang H, Deng Q, Fu C, Wang Y, Li R, Liu M, Pan W, Wang P.
    Cell Res; 2013 Jun 03; 23(6):803-19. PubMed ID: 23507969
    [Abstract] [Full Text] [Related]

  • 19. Ehrlichia chaffeensis TRP120-mediated ubiquitination and proteasomal degradation of tumor suppressor FBW7 increases oncoprotein stability and promotes infection.
    Wang JY, Zhu B, Patterson LL, Rogan MR, Kibler CE, McBride JW.
    PLoS Pathog; 2020 Apr 03; 16(4):e1008541. PubMed ID: 32353058
    [Abstract] [Full Text] [Related]

  • 20. Fbw7 dimerization determines the specificity and robustness of substrate degradation.
    Welcker M, Larimore EA, Swanger J, Bengoechea-Alonso MT, Grim JE, Ericsson J, Zheng N, Clurman BE.
    Genes Dev; 2013 Dec 01; 27(23):2531-6. PubMed ID: 24298052
    [Abstract] [Full Text] [Related]

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