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167 related items for PubMed ID: 25729330

  • 1. Differential effects of HIF-α isoforms on apoptosis in renal carcinoma cell lines.
    Doonachar A, Gallo MD, Doukas D, Pasricha R, Lantsberg I, Schoenfeld AR.
    Cancer Cell Int; 2015; 15():23. PubMed ID: 25729330
    [Abstract] [Full Text] [Related]

  • 2. Up-regulation of hypoxia-inducible factors HIF-1alpha and HIF-2alpha under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function.
    Krieg M, Haas R, Brauch H, Acker T, Flamme I, Plate KH.
    Oncogene; 2000 Nov 16; 19(48):5435-43. PubMed ID: 11114720
    [Abstract] [Full Text] [Related]

  • 3. The relationship of erythropoietin overexpression with von Hippel-Lindau tumour suppressor gene mutations between hypoxia-inducible factor-1α and -2α in sporadic clear cell renal carcinoma.
    Gong K, Zhang N, Zhang K, Na Y.
    Int J Mol Med; 2010 Dec 16; 26(6):907-12. PubMed ID: 21042786
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  • 4. [The expression of hypoxia inducible factor-1,2 alpha in sporadic clear cell renal cell carcinoma and their relationships to the mutations of von Hippel-Lindau gene].
    Gong K, Zhang N, Na X, Wu G, Yang XY, Xin DQ, Na YQ.
    Zhonghua Wai Ke Za Zhi; 2005 Mar 15; 43(6):390-3. PubMed ID: 15854350
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  • 6. Effects of ras and von Hippel-Lindau (VHL) gene mutations on hypoxia-inducible factor (HIF)-1alpha, HIF-2alpha, and vascular endothelial growth factor expression and their regulation by the phosphatidylinositol 3'-kinase/Akt signaling pathway.
    Blancher C, Moore JW, Robertson N, Harris AL.
    Cancer Res; 2001 Oct 01; 61(19):7349-55. PubMed ID: 11585776
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  • 7. Role of hypoxia-inducible factor (HIF)-1alpha versus HIF-2alpha in the regulation of HIF target genes in response to hypoxia, insulin-like growth factor-I, or loss of von Hippel-Lindau function: implications for targeting the HIF pathway.
    Carroll VA, Ashcroft M.
    Cancer Res; 2006 Jun 15; 66(12):6264-70. PubMed ID: 16778202
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  • 8. Constitutive activation of hypoxia-inducible genes related to overexpression of hypoxia-inducible factor-1alpha in clear cell renal carcinomas.
    Wiesener MS, Münchenhagen PM, Berger I, Morgan NV, Roigas J, Schwiertz A, Jürgensen JS, Gruber G, Maxwell PH, Löning SA, Frei U, Maher ER, Gröne HJ, Eckardt KU.
    Cancer Res; 2001 Jul 01; 61(13):5215-22. PubMed ID: 11431362
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  • 10. Differences in regulation of tight junctions and cell morphology between VHL mutations from disease subtypes.
    Bangiyeva V, Rosenbloom A, Alexander AE, Isanova B, Popko T, Schoenfeld AR.
    BMC Cancer; 2009 Jul 14; 9():229. PubMed ID: 19602254
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  • 11. The pVHL-associated SCF ubiquitin ligase complex: molecular genetic analysis of elongin B and C, Rbx1 and HIF-1alpha in renal cell carcinoma.
    Clifford SC, Astuti D, Hooper L, Maxwell PH, Ratcliffe PJ, Maher ER.
    Oncogene; 2001 Aug 16; 20(36):5067-74. PubMed ID: 11526493
    [Abstract] [Full Text] [Related]

  • 12. Stromal cell-derived factor-1alpha and CXCR4 expression in hemangioblastoma and clear cell-renal cell carcinoma: von Hippel-Lindau loss-of-function induces expression of a ligand and its receptor.
    Zagzag D, Krishnamachary B, Yee H, Okuyama H, Chiriboga L, Ali MA, Melamed J, Semenza GL.
    Cancer Res; 2005 Jul 15; 65(14):6178-88. PubMed ID: 16024619
    [Abstract] [Full Text] [Related]

  • 13. Silencing of epidermal growth factor receptor suppresses hypoxia-inducible factor-2-driven VHL-/- renal cancer.
    Smith K, Gunaratnam L, Morley M, Franovic A, Mekhail K, Lee S.
    Cancer Res; 2005 Jun 15; 65(12):5221-30. PubMed ID: 15958567
    [Abstract] [Full Text] [Related]

  • 14. Factor inhibiting HIF (FIH-1) promotes renal cancer cell survival by protecting cells from HIF-1α-mediated apoptosis.
    Khan MN, Bhattacharyya T, Andrikopoulos P, Esteban MA, Barod R, Connor T, Ashcroft M, Maxwell PH, Kiriakidis S.
    Br J Cancer; 2011 Mar 29; 104(7):1151-9. PubMed ID: 21386837
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  • 15. Epigenetic regulation of HIF-1α in renal cancer cells involves HIF-1α/2α binding to a reverse hypoxia-response element.
    Xu J, Wang B, Xu Y, Sun L, Tian W, Shukla D, Barod R, Grillari J, Grillari-Voglauer R, Maxwell PH, Esteban MA.
    Oncogene; 2012 Feb 23; 31(8):1065-72. PubMed ID: 21841824
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  • 16. Tuberous sclerosis complex protein 1 expression is affected by VHL Gene alterations and HIF-1α production in sporadic clear-cell renal cell carcinoma.
    Damjanovic SS, Ilic BB, Beleslin Cokic BB, Antic JA, Bankovic JZ, Milicevic IT, Rodic GS, Ilic DS, Todorovic VN, Puskas N, Tulic CD.
    Exp Mol Pathol; 2016 Dec 23; 101(3):323-331. PubMed ID: 27845047
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  • 17. Renal cancer cells lacking hypoxia inducible factor (HIF)-1alpha expression maintain vascular endothelial growth factor expression through HIF-2alpha.
    Shinojima T, Oya M, Takayanagi A, Mizuno R, Shimizu N, Murai M.
    Carcinogenesis; 2007 Mar 23; 28(3):529-36. PubMed ID: 16920734
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  • 18. Role of the C-terminal alpha-helical domain of the von Hippel-Lindau protein in its E3 ubiquitin ligase activity.
    Lewis MD, Roberts BJ.
    Oncogene; 2004 Mar 25; 23(13):2315-23. PubMed ID: 14691445
    [Abstract] [Full Text] [Related]

  • 19. Expression of hypoxia-inducible factors in human renal cancer: relationship to angiogenesis and to the von Hippel-Lindau gene mutation.
    Turner KJ, Moore JW, Jones A, Taylor CF, Cuthbert-Heavens D, Han C, Leek RD, Gatter KC, Maxwell PH, Ratcliffe PJ, Cranston D, Harris AL.
    Cancer Res; 2002 May 15; 62(10):2957-61. PubMed ID: 12019178
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