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Journal Abstract Search

541 related items for PubMed ID: 25731175

  • 1. Notum deacylates Wnt proteins to suppress signalling activity.
    Kakugawa S, Langton PF, Zebisch M, Howell S, Chang TH, Liu Y, Feizi T, Bineva G, O'Reilly N, Snijders AP, Jones EY, Vincent JP.
    Nature; 2015 Mar 12; 519(7542):187-192. PubMed ID: 25731175
    [Abstract] [Full Text] [Related]

  • 2. Mammalian Notum induces the release of glypicans and other GPI-anchored proteins from the cell surface.
    Traister A, Shi W, Filmus J.
    Biochem J; 2008 Mar 15; 410(3):503-11. PubMed ID: 17967162
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  • 3. Glypicans shield the Wnt lipid moiety to enable signalling at a distance.
    McGough IJ, Vecchia L, Bishop B, Malinauskas T, Beckett K, Joshi D, O'Reilly N, Siebold C, Jones EY, Vincent JP.
    Nature; 2020 Sep 15; 585(7823):85-90. PubMed ID: 32699409
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  • 5. Cell signalling: Disarming Wnt.
    Nusse R.
    Nature; 2015 Mar 12; 519(7542):163-4. PubMed ID: 25731170
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  • 7. A zebrafish Notum homolog specifically blocks the Wnt/β-catenin signaling pathway.
    Flowers GP, Topczewska JM, Topczewski J.
    Development; 2012 Jul 12; 139(13):2416-25. PubMed ID: 22669824
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  • 8. Development: Switching off WNT with precision.
    Baumann K.
    Nat Rev Mol Cell Biol; 2015 Apr 12; 16(4):204. PubMed ID: 25785717
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  • 12. Detailed expression profile of the six Glypicans and their modifying enzyme, Notum during chick limb and feather development.
    Saad K, Theis S, Otto A, Luke G, Patel K.
    Gene; 2017 Apr 30; 610():71-79. PubMed ID: 28192166
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  • 14. Regulation of Wnt distribution and function by Drosophila glypicans.
    Waghmare I, Page-McCaw A.
    J Cell Sci; 2022 Feb 01; 135(3):. PubMed ID: 35112708
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  • 15. NOTUM from Apc-mutant cells biases clonal competition to initiate cancer.
    Flanagan DJ, Pentinmikko N, Luopajärvi K, Willis NJ, Gilroy K, Raven AP, Mcgarry L, Englund JI, Webb AT, Scharaw S, Nasreddin N, Hodder MC, Ridgway RA, Minnee E, Sphyris N, Gilchrist E, Najumudeen AK, Romagnolo B, Perret C, Williams AC, Clevers H, Nummela P, Lähde M, Alitalo K, Hietakangas V, Hedley A, Clark W, Nixon C, Kirschner K, Jones EY, Ristimäki A, Leedham SJ, Fish PV, Vincent JP, Katajisto P, Sansom OJ.
    Nature; 2021 Jun 01; 594(7863):430-435. PubMed ID: 34079124
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  • 16. Structural Insights into Notum Covalent Inhibition.
    Zhao Y, Svensson F, Steadman D, Frew S, Monaghan A, Bictash M, Moreira T, Chalk R, Lu W, Fish PV, Jones EY.
    J Med Chem; 2021 Aug 12; 64(15):11354-11363. PubMed ID: 34292747
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  • 17. Extracellular carriers control lipid-dependent secretion, delivery, and activity of WNT morphogens.
    de Almeida Magalhaes T, Liu J, Chan C, Borges KS, Zhang J, Kane AJ, Wierbowski BM, Ge Y, Liu Z, Mannam P, Zeve D, Weiss R, Breault DT, Huang P, Salic A.
    Dev Cell; 2024 Jan 22; 59(2):244-261.e6. PubMed ID: 38154460
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  • 18. Design of a Potent, Selective, and Brain-Penetrant Inhibitor of Wnt-Deactivating Enzyme Notum by Optimization of a Crystallographic Fragment Hit.
    Willis NJ, Mahy W, Sipthorp J, Zhao Y, Woodward HL, Atkinson BN, Bayle ED, Svensson F, Frew S, Jeganathan F, Monaghan A, Benvegnù S, Jolly S, Vecchia L, Ruza RR, Kjær S, Howell S, Snijders AP, Bictash M, Salinas PC, Vincent JP, Jones EY, Whiting P, Fish PV.
    J Med Chem; 2022 May 26; 65(10):7212-7230. PubMed ID: 35536179
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  • 19. Generation of Mice with Hepatocyte-Specific Conditional Deletion of Notum.
    Canal F, Charawi S, Grimber G, Houbron C, Drouet V, Colnot S, Terris B, Cavard C, Perret C.
    PLoS One; 2016 May 26; 11(3):e0150997. PubMed ID: 26974334
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