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Journal Abstract Search


428 related items for PubMed ID: 25731850

  • 1. Inhibition of the malate-aspartate shuttle in mouse pancreatic islets abolishes glucagon secretion without affecting insulin secretion.
    Stamenkovic JA, Andersson LE, Adriaenssens AE, Bagge A, Sharoyko VV, Gribble F, Reimann F, Wollheim CB, Mulder H, Spégel P.
    Biochem J; 2015 May 15; 468(1):49-63. PubMed ID: 25731850
    [Abstract] [Full Text] [Related]

  • 2. Silencing of the mitochondrial NADH shuttle component aspartate-glutamate carrier AGC1/Aralar1 in INS-1E cells and rat islets.
    Casimir M, Rubi B, Frigerio F, Chaffard G, Maechler P.
    Biochem J; 2009 Dec 10; 424(3):459-66. PubMed ID: 19764902
    [Abstract] [Full Text] [Related]

  • 3. The malate-aspartate NADH shuttle member Aralar1 determines glucose metabolic fate, mitochondrial activity, and insulin secretion in beta cells.
    Rubi B, del Arco A, Bartley C, Satrustegui J, Maechler P.
    J Biol Chem; 2004 Dec 31; 279(53):55659-66. PubMed ID: 15494407
    [Abstract] [Full Text] [Related]

  • 4. Metabolomic analyses reveal profound differences in glycolytic and tricarboxylic acid cycle metabolism in glucose-responsive and -unresponsive clonal β-cell lines.
    Spégel P, Malmgren S, Sharoyko VV, Newsholme P, Koeck T, Mulder H.
    Biochem J; 2011 Apr 01; 435(1):277-84. PubMed ID: 21208194
    [Abstract] [Full Text] [Related]

  • 5. Raldh3 expression in diabetic islets reciprocally regulates secretion of insulin and glucagon from pancreatic islets.
    Shimamura M, Karasawa H, Sakakibara S, Shinagawa A.
    Biochem Biophys Res Commun; 2010 Oct 08; 401(1):79-84. PubMed ID: 20833146
    [Abstract] [Full Text] [Related]

  • 6. Processing of proglucagon to GLP-1 in pancreatic α-cells: is this a paracrine mechanism enabling GLP-1 to act on β-cells?
    Whalley NM, Pritchard LE, Smith DM, White A.
    J Endocrinol; 2011 Oct 08; 211(1):99-106. PubMed ID: 21795304
    [Abstract] [Full Text] [Related]

  • 7. Feasibility of a mitochondrial pyruvate malate shuttle in pancreatic islets. Further implication of cytosolic NADPH in insulin secretion.
    MacDonald MJ.
    J Biol Chem; 1995 Aug 25; 270(34):20051-8. PubMed ID: 7650022
    [Abstract] [Full Text] [Related]

  • 8. Evidence of enhancement of malate-aspartate shuttle activity in beta cells of streptozotocin-induced non-insulin-dependent diabetic rats.
    Song DK, Ahn YH, Bae JH, Park WK, Hong YS, Ho WK, Earm YE.
    Metabolism; 2000 Jan 25; 49(1):92-6. PubMed ID: 10647070
    [Abstract] [Full Text] [Related]

  • 9. [Role of the NADH shuttle system in glucose-induced insulin secretion].
    Eto K, Kadowaki T.
    Nihon Rinsho; 1999 Mar 25; 57(3):503-14. PubMed ID: 10199125
    [Abstract] [Full Text] [Related]

  • 10. The importance of redox shuttles to pancreatic beta-cell energy metabolism and function.
    Bender K, Newsholme P, Brennan L, Maechler P.
    Biochem Soc Trans; 2006 Nov 25; 34(Pt 5):811-4. PubMed ID: 17052204
    [Abstract] [Full Text] [Related]

  • 11. CART is overexpressed in human type 2 diabetic islets and inhibits glucagon secretion and increases insulin secretion.
    Abels M, Riva M, Bennet H, Ahlqvist E, Dyachok O, Nagaraj V, Shcherbina L, Fred RG, Poon W, Sörhede-Winzell M, Fadista J, Lindqvist A, Kask L, Sathanoori R, Dekker-Nitert M, Kuhar MJ, Ahrén B, Wollheim CB, Hansson O, Tengholm A, Fex M, Renström E, Groop L, Lyssenko V, Wierup N.
    Diabetologia; 2016 Sep 25; 59(9):1928-37. PubMed ID: 27338624
    [Abstract] [Full Text] [Related]

  • 12. Role for malic enzyme, pyruvate carboxylation, and mitochondrial malate import in glucose-stimulated insulin secretion.
    Heart E, Cline GW, Collis LP, Pongratz RL, Gray JP, Smith PJ.
    Am J Physiol Endocrinol Metab; 2009 Jun 25; 296(6):E1354-62. PubMed ID: 19293334
    [Abstract] [Full Text] [Related]

  • 13. Dapagliflozin promotes beta cell regeneration by inducing pancreatic endocrine cell phenotype conversion in type 2 diabetic mice.
    Wei R, Cui X, Feng J, Gu L, Lang S, Wei T, Yang J, Liu J, Le Y, Wang H, Yang K, Hong T.
    Metabolism; 2020 Oct 25; 111():154324. PubMed ID: 32712220
    [Abstract] [Full Text] [Related]

  • 14. Low lactate dehydrogenase and high mitochondrial glycerol phosphate dehydrogenase in pancreatic beta-cells. Potential role in nutrient sensing.
    Sekine N, Cirulli V, Regazzi R, Brown LJ, Gine E, Tamarit-Rodriguez J, Girotti M, Marie S, MacDonald MJ, Wollheim CB.
    J Biol Chem; 1994 Feb 18; 269(7):4895-902. PubMed ID: 8106462
    [Abstract] [Full Text] [Related]

  • 15. Dapagliflozin Does Not Directly Affect Human α or β Cells.
    Dai C, Walker JT, Shostak A, Bouchi Y, Poffenberger G, Hart NJ, Jacobson DA, Calcutt MW, Bottino R, Greiner DL, Shultz LD, McGuinness OP, Dean ED, Powers AC.
    Endocrinology; 2020 Aug 01; 161(8):. PubMed ID: 32428240
    [Abstract] [Full Text] [Related]

  • 16. Per-arnt-sim (PAS) domain-containing protein kinase is downregulated in human islets in type 2 diabetes and regulates glucagon secretion.
    da Silva Xavier G, Farhan H, Kim H, Caxaria S, Johnson P, Hughes S, Bugliani M, Marselli L, Marchetti P, Birzele F, Sun G, Scharfmann R, Rutter J, Siniakowicz K, Weir G, Parker H, Reimann F, Gribble FM, Rutter GA.
    Diabetologia; 2011 Apr 01; 54(4):819-27. PubMed ID: 21181396
    [Abstract] [Full Text] [Related]

  • 17. The oscillatory behavior of pancreatic islets from mice with mitochondrial glycerol-3-phosphate dehydrogenase knockout.
    Ravier MA, Eto K, Jonkers FC, Nenquin M, Kadowaki T, Henquin JC.
    J Biol Chem; 2000 Jan 21; 275(3):1587-93. PubMed ID: 10636849
    [Abstract] [Full Text] [Related]

  • 18. NADH shuttle system regulates K(ATP) channel-dependent pathway and steps distal to cytosolic Ca(2+) concentration elevation in glucose-induced insulin secretion.
    Eto K, Suga S, Wakui M, Tsubamoto Y, Terauchi Y, Taka J, Aizawa S, Noda M, Kimura S, Kasai H, Kadowaki T.
    J Biol Chem; 1999 Sep 03; 274(36):25386-92. PubMed ID: 10464266
    [Abstract] [Full Text] [Related]

  • 19. Nesfatin-1 stimulates glucagon and insulin secretion and beta cell NUCB2 is reduced in human type 2 diabetic subjects.
    Riva M, Nitert MD, Voss U, Sathanoori R, Lindqvist A, Ling C, Wierup N.
    Cell Tissue Res; 2011 Dec 03; 346(3):393-405. PubMed ID: 22108805
    [Abstract] [Full Text] [Related]

  • 20. Glucotoxicity and α cell dysfunction: involvement of the PI3K/Akt pathway in glucose-induced insulin resistance in rat islets and clonal αTC1-6 cells.
    Shen XX, Li HL, Pan L, Hong J, Xiao J, Hermansen K, Jeppesen PB, Li GW.
    Endocr Res; 2012 Dec 03; 37(1):12-24. PubMed ID: 22007944
    [Abstract] [Full Text] [Related]


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