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393 related items for PubMed ID: 25732194

  • 1. Dependency of 2-methoxyestradiol-induced mitochondrial apoptosis on mitotic spindle network impairment and prometaphase arrest in human Jurkat T cells.
    Lee ST, Lee JY, Han CR, Kim YH, Jun do Y, Taub D, Kim YH.
    Biochem Pharmacol; 2015 Apr 15; 94(4):257-69. PubMed ID: 25732194
    [Abstract] [Full Text] [Related]

  • 2. Prometaphase arrest-dependent phosphorylation of Bcl-2 family proteins and activation of mitochondrial apoptotic pathway are associated with 17α-estradiol-induced apoptosis in human Jurkat T cells.
    Han CR, Jun do Y, Kim YH, Lee JY, Kim YH.
    Biochim Biophys Acta; 2013 Oct 15; 1833(10):2220-32. PubMed ID: 23707954
    [Abstract] [Full Text] [Related]

  • 3. Inhibition of JNK2 and JNK3 by JNK inhibitor IX induces prometaphase arrest-dependent apoptotic cell death in human Jurkat T cells.
    Jang WY, Lee JY, Lee ST, Jun do Y, Kim YH.
    Biochem Biophys Res Commun; 2014 Sep 26; 452(3):845-51. PubMed ID: 25218503
    [Abstract] [Full Text] [Related]

  • 4. Prometaphase arrest-dependent phosphorylation of Bcl-2 and Bim reduces the association of Bcl-2 with Bak or Bim, provoking Bak activation and mitochondrial apoptosis in nocodazole-treated Jurkat T cells.
    Han CR, Jun do Y, Lee JY, Kim YH.
    Apoptosis; 2014 Jan 26; 19(1):224-40. PubMed ID: 24166139
    [Abstract] [Full Text] [Related]

  • 5. Cis-trimethoxy resveratrol induces intrinsic apoptosis via prometaphase arrest and prolonged CDK1 activation pathway in human Jurkat T cells.
    Kim CE, Jun DY, Kim JS, Kim YH.
    Oncotarget; 2018 Jan 12; 9(4):4969-4984. PubMed ID: 29435156
    [Abstract] [Full Text] [Related]

  • 6. Kaempferol Activates G₂-Checkpoint of the Cell Cycle Resulting in G₂-Arrest and Mitochondria-Dependent Apoptosis in Human Acute Leukemia Jurkat T Cells.
    Kim KY, Jang WY, Lee JY, Jun do Y, Ko JY, Yun YH, Kim YH.
    J Microbiol Biotechnol; 2016 Feb 12; 26(2):287-94. PubMed ID: 26699757
    [Abstract] [Full Text] [Related]

  • 7. Cytoprotective effect of 2-carbomethoxy-2,3-epoxy-3-prenyl-1,4-naphthoquinone (CMEP-NQ) is mediated by the inhibition of BAK-dependent mitochondrial apoptosis pathway.
    Jun DY, Jang WY, Kim KY, Woo MH, Kim YH.
    PLoS One; 2018 Feb 12; 13(10):e0204585. PubMed ID: 30273361
    [Abstract] [Full Text] [Related]

  • 8. Tumor suppressor protein p53 promotes 2-methoxyestradiol-induced activation of Bak and Bax, leading to mitochondria-dependent apoptosis in human colon cancer HCT116 cells.
    Lee JY, Jee SB, Park WY, Choi YJ, Kim B, Kim YH, Jun do Y, Kim YH.
    J Microbiol Biotechnol; 2014 Dec 28; 24(12):1654-63. PubMed ID: 25179905
    [Abstract] [Full Text] [Related]

  • 9. Induction of microtubule-damage, mitotic arrest, Bcl-2 phosphorylation, Bak activation, and mitochondria-dependent caspase cascade is involved in human Jurkat T-cell apoptosis by aruncin B from Aruncus dioicus var. kamtschaticus.
    Han CR, Jun do Y, Woo HJ, Jeong SY, Woo MH, Kim YH.
    Bioorg Med Chem Lett; 2012 Jan 15; 22(2):945-53. PubMed ID: 22197393
    [Abstract] [Full Text] [Related]

  • 10. CDK1 switches mitotic arrest to apoptosis by phosphorylating Bcl-2/Bax family proteins during treatment with microtubule interfering agents.
    Zhou L, Cai X, Han X, Xu N, Chang DC.
    Cell Biol Int; 2014 Jun 15; 38(6):737-46. PubMed ID: 24677263
    [Abstract] [Full Text] [Related]

  • 11. Temporal relationship of CDK1 activation and mitotic arrest to cytosolic accumulation of cytochrome C and caspase-3 activity during Taxol-induced apoptosis of human AML HL-60 cells.
    Ibrado AM, Kim CN, Bhalla K.
    Leukemia; 1998 Dec 15; 12(12):1930-6. PubMed ID: 9844922
    [Abstract] [Full Text] [Related]

  • 12. Investigation of anti-tumor mechanisms of K2154: characterization of tubulin isotypes, mitotic arrest and apoptotic machinery.
    Lu PH, Kung FL, Kuo SC, Chueh SC, Guh JH.
    Naunyn Schmiedebergs Arch Pharmacol; 2006 Dec 15; 374(3):223-33. PubMed ID: 17102938
    [Abstract] [Full Text] [Related]

  • 13. MJ-29 inhibits tubulin polymerization, induces mitotic arrest, and triggers apoptosis via cyclin-dependent kinase 1-mediated Bcl-2 phosphorylation in human leukemia U937 cells.
    Yang JS, Hour MJ, Huang WW, Lin KL, Kuo SC, Chung JG.
    J Pharmacol Exp Ther; 2010 Aug 15; 334(2):477-88. PubMed ID: 20463006
    [Abstract] [Full Text] [Related]

  • 14. Mollugin induces apoptosis in human Jurkat T cells through endoplasmic reticulum stress-mediated activation of JNK and caspase-12 and subsequent activation of mitochondria-dependent caspase cascade regulated by Bcl-xL.
    Kim SM, Park HS, Jun DY, Woo HJ, Woo MH, Yang CH, Kim YH.
    Toxicol Appl Pharmacol; 2009 Dec 01; 241(2):210-20. PubMed ID: 19716835
    [Abstract] [Full Text] [Related]

  • 15. Apoptogenic activity of 2α,3α-dihydroxyurs-12-ene-28-oic acid from Prunella vulgaris var. lilacina is mediated via mitochondria-dependent activation of caspase cascade regulated by Bcl-2 in human acute leukemia Jurkat T cells.
    Woo HJ, Jun do Y, Lee JY, Woo MH, Yang CH, Kim YH.
    J Ethnopharmacol; 2011 Jun 01; 135(3):626-35. PubMed ID: 21473903
    [Abstract] [Full Text] [Related]

  • 16. Role of cyclin B1/Cdc2 in mediating Bcl-XL phosphorylation and apoptotic cell death following nocodazole-induced mitotic arrest.
    Choi HJ, Zhu BT.
    Mol Carcinog; 2014 Feb 01; 53(2):125-37. PubMed ID: 22949227
    [Abstract] [Full Text] [Related]

  • 17. Repurposing of phentolamine as a potential anticancer agent against human castration-resistant prostate cancer: A central role on microtubule stabilization and mitochondrial apoptosis pathway.
    Ho CH, Hsu JL, Liu SP, Hsu LC, Chang WL, Chao CC, Guh JH.
    Prostate; 2015 Sep 01; 75(13):1454-66. PubMed ID: 26180030
    [Abstract] [Full Text] [Related]

  • 18. Cytotoxicity of diacetoxyscirpenol is associated with apoptosis by activation of caspase-8 and interruption of cell cycle progression by down-regulation of cdk4 and cyclin B1 in human Jurkat T cells.
    Jun DY, Kim JS, Park HS, Song WS, Bae YS, Kim YH.
    Toxicol Appl Pharmacol; 2007 Jul 15; 222(2):190-201. PubMed ID: 17559898
    [Abstract] [Full Text] [Related]

  • 19. Quinolone analogue inhibits tubulin polymerization and induces apoptosis via Cdk1-involved signaling pathways.
    Chen YC, Lu PH, Pan SL, Teng CM, Kuo SC, Lin TP, Ho YF, Huang YC, Guh JH.
    Biochem Pharmacol; 2007 Jun 30; 74(1):10-9. PubMed ID: 17475221
    [Abstract] [Full Text] [Related]

  • 20. 6,7-Dimethoxy-3-(3-methoxyphenyl)isoquinolin-1-amine induces mitotic arrest and apoptotic cell death through the activation of spindle assembly checkpoint in human cervical cancer cells.
    Chung KS, Choi HE, Shin JS, Cho YW, Choi JH, Cho WJ, Lee KT.
    Carcinogenesis; 2013 Aug 30; 34(8):1852-60. PubMed ID: 23615402
    [Abstract] [Full Text] [Related]

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